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Chuyu Chen
Chuyu Chen
Verified email at northwestern.edu
Title
Cited by
Cited by
Year
(G2019S) LRRK2 activates MKK4-JNK pathway and causes degeneration of SN dopaminergic neurons in a transgenic mouse model of PD
CY Chen, YH Weng, KY Chien, KJ Lin, TH Yeh, YP Cheng, CS Lu, ...
Cell Death & Differentiation 19 (10), 1623-1633, 2012
2052012
(G2019S) LRRK2 causes early-phase dysfunction of SNpc dopaminergic neurons and impairment of corticostriatal long-term depression in the PD transgenic mouse
JS Chou, CY Chen, YL Chen, YH Weng, TH Yeh, CS Lu, YM Chang, ...
Neurobiology of disease 68, 190-199, 2014
702014
Glucocerebrosidase haploinsufficiency in A53T α-synuclein mice impacts disease onset and course
N Tayebi, L Parisiadou, B Berhe, AN Gonzalez, J Serra-Vinardell, ...
Molecular genetics and metabolism 122 (4), 198-208, 2017
342017
Pathway-specific dysregulation of striatal excitatory synapses by LRRK2 mutations
C Chen, G Soto, V Dumrongprechachan, N Bannon, S Kang, ...
Elife 9, e58997, 2020
292020
(R1441C) LRRK2 induces the degeneration of SN dopaminergic neurons and alters the expression of genes regulating neuronal survival in a transgenic mouse model
YH Weng, CY Chen, KJ Lin, YL Chen, TH Yeh, T Hsiao, J Chen, CS Lu, ...
Experimental Neurology 275, 104-115, 2016
252016
NQO1 regulates mitotic progression and response to mitotic stress through modulating SIRT2 activity
HJ Kang, HY Song, MA Ahmed, Y Guo, M Zhang, C Chen, M Cristofanilli, ...
Free Radical Biology and Medicine 126, 358-371, 2018
122018
R1441C and G2019S LRRK2 knockin mice have distinct striatal molecular, physiological, and behavioral alterations
HS Xenias, C Chen, S Kang, S Cherian, X Situ, B Shanmugasundaram, ...
Communications biology 5 (1), 1211, 2022
42022
Pathogenic LRRK2 R1441C mutation is associated with striatal alterations
HS Xenias, C Chen, S Kang, S Cherian, X Situ, B Shanmugasundaram, ...
bioRxiv, 2020.03. 11.986455, 2020
42020
Closing the structure-to-function gap for LRRK2
V Tokars, C Chen, L Parisiadou
Trends in Biochemical Sciences 47 (3), 187-188, 2022
32022
LRRK2 regulates synaptic function through BDNF signaling and actin cytoskeleton
G Tombesi, S Kompella, G Favetta, C Chen, Y Zhao, M Sevegnani, ...
bioRxiv, 2022.10. 31.514622, 2022
2022
Viral-mediated short-hairpin RNA knockdown
C Chen, L Parisiadou
2022
Behavioral tests in rodents coupled with dopamine signaling manipulations
C Chen, L Parisiadou
2022
Fractionation of synaptosomes
C Chen, C Smith, L Parisiadou
2022
Protocol for mixed cortical striatal cell culture
C Chen, C Smith, L Parisiadou
2022
APEX2 labelling and screening for biotinylated proteins by proteomics
C Chen, C Smith, L Parisiadou
2022
REVEALING THE MOLECULAR MECHANISM UNDER GENETIC VARIANTS LOCI RS34767465 IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE.
H Zhang, T De, C Chen, L Parisiadou, M Perera
CLINICAL PHARMACOLOGY & THERAPEUTICS 105, S116-S116, 2019
2019
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Articles 1–16