Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells E Ferretti, E De Smaele, E Miele, P Laneve, A Po, M Pelloni, A Paganelli, ... The EMBO journal 27 (19), 2616-2627, 2008 | 398 | 2008 |
MicroRNA profiling in human medulloblastoma E Ferretti, E De Smaele, A Po, L Di Marcotullio, E Tosi, MSB Espinola, ... International journal of cancer 124 (3), 568-577, 2009 | 347 | 2009 |
Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination LD Marcotullio, E Ferretti, A Greco, E De Smaele, A Po, MA Sico, ... Nature cell biology 8 (12), 1415-1423, 2006 | 347 | 2006 |
Hedgehog controls neural stem cells through p53‐independent regulation of Nanog A Po, E Ferretti, E Miele, E De Smaele, A Paganelli, G Canettieri, S Coni, ... The EMBO journal 29 (15), 2646-2658, 2010 | 253 | 2010 |
Gli1/DNA interaction is a druggable target for Hedgehog‐dependent tumors P Infante, M Mori, R Alfonsi, F Ghirga, F Aiello, S Toscano, C Ingallina, ... The EMBO journal 34 (2), 200-217, 2015 | 183 | 2015 |
MicroRNA-124a is hyperexpressed in type 2 diabetic human pancreatic islets and negatively regulates insulin secretion G Sebastiani, A Po, E Miele, G Ventriglia, E Ceccarelli, M Bugliani, ... Acta Diabetologica 52, 523-530, 2015 | 150 | 2015 |
Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma A Po, M Silvano, E Miele, C Capalbo, A Eramo, V Salvati, M Todaro, ... Oncogene 36 (32), 4641-4652, 2017 | 100 | 2017 |
PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress D Mazza, P Infante, V Colicchia, A Greco, R Alfonsi, M Siler, L Antonucci, ... Cell Death & Differentiation 20 (12), 1688-1697, 2013 | 94 | 2013 |
Adoptive immunotherapy using PRAME-specific T cells in medulloblastoma D Orlando, E Miele, B De Angelis, M Guercio, I Boffa, M Sinibaldi, A Po, ... Cancer research 78 (12), 3337-3349, 2018 | 84 | 2018 |
Notch signaling is involved in expression of thyrocyte differentiation markers and is down-regulated in thyroid tumors E Ferretti, E Tosi, A Po, A Scipioni, R Morisi, MS Espinola, D Russo, ... The Journal of Clinical Endocrinology & Metabolism 93 (10), 4080-4087, 2008 | 81 | 2008 |
microRNA‐17‐92 cluster is a direct Nanog target and controls neural stem cell through Trp53inp1 N Garg, A Po, E Miele, AF Campese, F Begalli, M Silvano, P Infante, ... The EMBO journal 32 (21), 2819-2832, 2013 | 73 | 2013 |
β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells E Miele, A Po, F Begalli, L Antonucci, A Mastronuzzi, CE Marras, A Carai, ... BMC cancer 17, 1-12, 2017 | 65 | 2017 |
An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma E De Smaele, C Fragomeli, E Ferretti, M Pelloni, A Po, G Canettieri, ... Neoplasia 10 (1), 89-IN36, 2008 | 63 | 2008 |
Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis P Infante, R Faedda, F Bernardi, F Bufalieri, L Lospinoso Severini, ... Nature communications 9 (1), 976, 2018 | 61 | 2018 |
Alternative splicing of the ErbB-4 cytoplasmic domain and its regulation by hedgehog signaling identify distinct medulloblastoma subsets E Ferretti, L Di Marcotullio, M Gessi, T Mattei, A Greco, A Po, E De Smaele, ... Oncogene 25 (55), 7267-7273, 2006 | 53 | 2006 |
The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells E Miele, S Valente, V Alfano, M Silvano, P Mellini, D Borovika, B Marrocco, ... Oncotarget 8 (40), 68557, 2017 | 52 | 2017 |
The long noncoding RNA linc-NeD125 controls the expression of medulloblastoma driver genes by microRNA sponge activity P Laneve, A Po, A Favia, I Legnini, V Alfano, J Rea, V Di Carlo, ... Oncotarget 8 (19), 31003, 2017 | 48 | 2017 |
High-throughput microRNA profiling of pediatric high-grade gliomas E Miele, FR Buttarelli, A Arcella, F Begalli, N Garg, M Silvano, A Po, ... Neuro-oncology 16 (2), 228-240, 2014 | 40 | 2014 |
IDO1 involvement in mTOR pathway: a molecular mechanism of resistance to mTOR targeting in medulloblastoma V Folgiero, E Miele, A Carai, E Ferretti, V Alfano, A Po, V Bertaina, ... Oncotarget 7 (33), 52900, 2016 | 39 | 2016 |
The tumor suppressor gene KCTD11 REN is regulated by Sp1 and methylation and its expression is reduced in tumors MM Mancarelli, F Zazzeroni, L Ciccocioppo, D Capece, A Po, S Murgo, ... Molecular cancer 9, 1-7, 2010 | 39 | 2010 |