| The lysosome as a command-and-control center for cellular metabolism CY Lim, R Zoncu Journal of Cell Biology 214 (6), 653-664, 2016 | 277 | 2016 |
| Lipid-overloaded enlarged adipocytes provoke insulin resistance independent of inflammation JI Kim, JY Huh, JH Sohn, SS Choe, YS Lee, CY Lim, A Jo, SB Park, ... Molecular and cellular biology 35 (10), 1686-1699, 2015 | 275 | 2015 |
| ER–lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann–Pick type C CY Lim, OB Davis, HR Shin, J Zhang, CA Berdan, X Jiang, JL Counihan, ... Nature cell biology 21 (10), 1206-1218, 2019 | 233 | 2019 |
| A unified approach to targeting the lysosome's degradative and growth signaling roles VW Rebecca, MC Nicastri, N McLaughlin, C Fennelly, Q McAfee, ... Cancer discovery 7 (11), 1266-1283, 2017 | 163 | 2017 |
| Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex RE Lawrence, SA Fromm, Y Fu, AL Yokom, DJ Kim, AM Thelen, ... Science 366 (6468), 971-977, 2019 | 124 | 2019 |
| NPC1-mTORC1 signaling couples cholesterol sensing to organelle homeostasis and is a targetable pathway in Niemann-Pick type C OB Davis, HR Shin, CY Lim, EY Wu, M Kukurugya, CF Maher, RM Perera, ... Developmental cell 56 (3), 260-276. e7, 2021 | 119 | 2021 |
| FoxO1 inhibits leptin regulation of pro-opiomelanocortin promoter activity by blocking STAT3 interaction with specificity protein 1 G Yang, CY Lim, C Li, X Xiao, GK Radda, C Li, X Cao, W Han Journal of biological chemistry 284 (6), 3719-3727, 2009 | 105 | 2009 |
| Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling CY Lim, X Bi, D Wu, JB Kim, PW Gunning, W Hong, W Han Nature communications 6 (1), 5951, 2015 | 92 | 2015 |
| Insulin-stimulated leptin secretion requires calcium and PI3K/Akt activation Y Wang, Y Ali, CY Lim, W Hong, ZP Pang, W Han Biochemical Journal 458 (3), 491-498, 2014 | 50 | 2014 |
| Glucose intolerance and impaired insulin secretion in pancreas-specific signal transducer and activator of transcription-3 knockout mice are associated with microvascular … E Kostromina, N Gustavsson, X Wang, CY Lim, GK Radda, C Li, W Han Endocrinology 151 (5), 2050-2059, 2010 | 43 | 2010 |
| Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1 HR Shin, YR Citron, L Wang, L Tribouillard, CS Goul, R Stipp, ... Science 377 (6612), 1290-1298, 2022 | 40 | 2022 |
| Neonatal overnutrition in mice exacerbates high-fat diet-induced metabolic perturbations Z Liu, CY Lim, MY Su, SL Soh, G Shui, MR Wenk, KL Grove, GK Radda, ... J Endocrinol 219 (2), 131-143, 2013 | 39 | 2013 |
| Arp2/3 complex regulates adipogenesis by controlling cortical actin remodelling W Yang, S Thein, CY Lim, RE Ericksen, S Sugii, F Xu, RC Robinson, ... Biochemical Journal 464 (2), 179-192, 2014 | 37 | 2014 |
| ArhGAP9, a novel MAP kinase docking protein, inhibits Erk and p38 activation through WW domain binding BK Ang, CY Lim, SS Koh, N Sivakumar, S Taib, KB Lim, S Ahmed, ... Journal of Molecular Signaling 2 (1), 1, 2007 | 27 | 2007 |
| Tmod3 phosphorylation mediates AMPK-dependent GLUT4 plasma membrane insertion in myoblasts MM Shrestha, CY Lim, X Bi, RC Robinson, W Han Frontiers in endocrinology 12, 653557, 2021 | 16 | 2021 |
| Adiponectin is released via a unique regulated exocytosis pathway from a pre-formed vesicle pool on insulin stimulation CY Lim, W Hong, W Han Biochemical Journal 471 (3), 381-389, 2015 | 15 | 2015 |
| A unified approach to targeting the lysosome’s degradative and growth signaling roles. Cancer Discov. 7, 1266–1283. doi: 10.1158/2159-8290 VW Rebecca, MC Nicastri, N McLaughlin, C Fennelly, Q McAfee, ... CD-17-0741, 2017 | 5 | 2017 |
| Tropomodulin3 as the link between insulin-activated AKT2 and cortical actin remodeling in preparation of GLUT4 exocytosis CY Lim, W Han Bioarchitecture 4 (6), 210-214, 2014 | 4 | 2014 |
| Actin Cytoskeletal Remodeling in the Regulation of Glucose Homeostasis MM Shrestha, CY Lim, W Han International Conference on Photonics and Imaging in Biology and Medicine …, 2017 | | 2017 |
| Chronic inflammation is associated with increased insulin resistance susceptibility in neonatally overfed mice XQ Xiao, MM Glavas, MA Kirigiti, S Fisher, AE Evans, PJ Enriori, CY Lim, ... The FASEB Journal 22, 115-115, 2008 | | 2008 |
