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Dr Felipe Guapo, PhD
Dr Felipe Guapo, PhD
Analytical Scientist, NIBRT
Verified email at nibrt.ie
Title
Cited by
Cited by
Year
Fast and efficient digestion of adeno associated virus (AAV) capsid proteins for liquid chromatography mass spectrometry (LC-MS) based peptide mapping and post translational …
F Guapo, L Strasser, S Millán-Martín, I Anderson, J Bones
Journal of pharmaceutical and biomedical analysis 207, 114427, 2022
192022
Proteomic landscape of adeno-associated virus (AAV)-producing HEK293 cells
L Strasser, S Boi, F Guapo, N Donohue, N Barron, A Rainbow-Fletcher, ...
International journal of molecular sciences 22 (21), 11499, 2021
162021
A native mass spectrometry-based assay for rapid assessment of the empty: full capsid ratio in adeno-associated virus gene therapy products
L Strasser, TE Morgan, F Guapo, F Füssl, D Forsey, I Anderson, J Bones
Analytical Chemistry 93 (38), 12817-12821, 2021
152021
SP3-based host cell protein monitoring in AAV-based gene therapy products using LC-MS/MS
J Smith, L Strasser, F Guapo, SG Milian, RO Snyder, J Bones
European Journal of Pharmaceutics and Biopharmaceutics 189, 276-280, 2023
32023
Mass spectrometry friendly pH-gradient anion exchange chromatography for the separation of full and empty adeno-associated virus (AAV) capsids
F Guapo, F Füssl, L Strasser, J Bones
Analytical Methods 15 (43), 5788-5792, 2023
22023
Development of a Rapid Adeno-Associated Virus (AAV) Identity Testing Platform through Comprehensive Intact Mass Analysis of Full-Length AAV Capsid Proteins
J Smith, F Guapo, L Strasser, S Millán-Martín, SG Milian, RO Snyder, ...
Journal of Proteome Research 23 (1), 161-174, 2023
12023
A Direct Comparison of rAAV5 Variants Derived from the Baculovirus Expression System Using LC-MS Workflows Demonstrates Key Differences in Overall Production Yield, Product …
F Guapo, N Donohue, L Strasser, S Boi, F Füssl, A Rainbow-Fletcher, ...
International Journal of Molecular Sciences 25 (5), 2785, 2024
2024
Annotation of the non-canonical translatome reveals that CHO cell microproteins are a new class of mAb drug product impurity
M Castro-Rivadeneyra, I Tzani, P Kelly, L Strasser, F Guapo, C Tierney, ...
2022
Found in translation: Microproteins are a new class of potential host cell impurity in mAb drug products
M Castro-Rivadeneyra, I Tzani, P Kelly, L Strasser, F Guapo, C Tierney, ...
bioRxiv, 2022.01. 20.475618, 2022
2022
A native mass spectrometry-based assay for rapid assessment of the empty/full capsid ratio in AAV gene therapy products
L Strasser, TE Morgan, F Guapo, F Füssl, D Forsey, I Anderson, J Bones
bioRxiv, 2021.07. 06.451264, 2021
2021
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