| In vivo CRISPR editing with no detectable genome-wide off-target mutations P Akcakaya, ML Bobbin, JA Guo, J Malagon-Lopez, K Clement, SP Garcia, ... Nature 561 (7723), 416-419, 2018 | 343 | 2018 |
| Activities and specificities of CRISPR/Cas9 and Cas12a nucleases for targeted mutagenesis in maize K Lee, Y Zhang, BP Kleinstiver, JA Guo, MJ Aryee, J Miller, A Malzahn, ... Plant biotechnology journal 17 (2), 362-372, 2019 | 232 | 2019 |
| Stromal vascular fraction: A regenerative reality? Part 1: Current concepts and review of the literature A Nguyen, J Guo, DA Banyard, D Fadavi, JD Toranto, GA Wirth, ... Journal of Plastic, Reconstructive & Aesthetic Surgery 69 (2), 170-179, 2016 | 219 | 2016 |
| Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment WL Hwang, KA Jagadeesh, JA Guo, HI Hoffman, P Yadollahpour, ... Nature Genetics 54 (8), 1178-1191, 2022 | 176 | 2022 |
| Stromal vascular fraction: a regenerative reality? Part 2: mechanisms of regenerative action J Guo, A Nguyen, DA Banyard, D Fadavi, JD Toranto, GA Wirth, ... Journal of Plastic, Reconstructive & Aesthetic Surgery 69 (2), 180-188, 2016 | 174 | 2016 |
| Defining CRISPR–Cas9 genome-wide nuclease activities with CIRCLE-seq CR Lazzarotto, NT Nguyen, X Tang, J Malagon-Lopez, JA Guo, MJ Aryee, ... Nature protocols 13 (11), 2615-2642, 2018 | 84 | 2018 |
| Therapeutic avenues for cancer neuroscience: translational frontiers and clinical opportunities DD Shi, JA Guo, HI Hoffman, J Su, M Mino-Kenudson, JL Barth, ... The Lancet Oncology 23 (2), e62-e74, 2022 | 55 | 2022 |
| Analysis of off-target effects in CRISPR-based gene drives in the human malaria mosquito WT Garrood, N Kranjc, K Petri, DY Kim, JA Guo, AM Hammond, ... Proceedings of the National Academy of Sciences 118 (22), e2004838117, 2021 | 41 | 2021 |
| Single-nucleus and spatial transcriptomics of archival pancreatic cancer reveals multi-compartment reprogramming after neoadjuvant treatment WL Hwang, KA Jagadeesh, JA Guo, HI Hoffman, P Yadollahpour, ... bioRxiv, 2020 | 37 | 2020 |
| CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data JY Hsu, CP Fulco, MA Cole, MC Canver, D Pellin, F Sher, R Farouni, ... Nature methods 15 (12), 992-993, 2018 | 36 | 2018 |
| Precise DNA cleavage using CRISPR-SpRYgests KA Christie, JA Guo, RA Silverstein, RM Doll, M Mabuchi, HE Stutzman, ... Nature Biotechnology, 1-8, 2022 | 35 | 2022 |
| Stromal vascular fraction: a regenerative reality A Nguyen, J Guo, DA Banyard, D Fadavi, JD Toranto, GA Wirth, ... Part 1: current concepts and review of the literature. J Plast Reconstr …, 0 | 26 | |
| Global-scale CRISPR gene editor specificity profiling by ONE-seq identifies population-specific, variant off-target effects K Petri, DY Kim, KE Sasaki, MC Canver, X Wang, H Shah, H Lee, ... bioRxiv, 2021 | 23 | 2021 |
| Racial Differences in Genomic Profiles of Breast Cancer N Goel, DY Kim, JA Guo, D Zhao, BA Mahal, M Alshalalfa JAMA network open 5 (3), e220573-e220573, 2022 | 18 | 2022 |
| Strategic sequences in fat graft survival J Guo, AD Widgerow, D Banyard, J Toranto, GA Wirth, K Paydar, ... Annals of plastic surgery 74 (3), 376-382, 2015 | 18 | 2015 |
| Pan-cancer Transcriptomic Predictors of Perineural Invasion Improve Occult Histopathologic DetectionGene Signatures of PNI Improve Occult Detection JA Guo, HI Hoffman, SG Shroff, P Chen, PG Hwang, DY Kim, DW Kim, ... Clinical cancer research 27 (10), 2807-2815, 2021 | 16 | 2021 |
| Treatment-associated remodeling of the pancreatic cancer endothelium at single-cell resolution C Shiau, J Su, J Guo, T Hong, J Wo, K Jagadeesh, W Hwang Frontiers in oncology 12, 2022 | 12 | 2022 |
| Refining the Molecular Framework for Pancreatic Cancer with Single-cell and Spatial TechnologiesSingle-cell Molecular Classification of Pancreatic Cancer JA Guo, HI Hoffman, CD Weekes, L Zheng, DT Ting, WL Hwang Clinical Cancer Research 27 (14), 3825-3833, 2021 | 10 | 2021 |
| Pan-Cancer Survival Classification With Clinicopathological and Targeted Gene Expression Features D Zhao, DY Kim, P Chen, P Yu, S Ho, SW Cheng, C Zhao, JA Guo, YR Li Cancer Informatics 20, 11769351211035137, 2021 | 6 | 2021 |
| Novel genomic signature predictive of response to immune checkpoint blockade: A pan-cancer analysis from project Genomics Evidence Neo-plasia Information Exchange (GENIE) N Swami, WL Hwang, JA Guo, H Hoffman, MC Abramowitz, Z Elbakouny, ... Cancer genetics 258, 61-68, 2021 | 4 | 2021 |
William L Hwang, MD, PhDPrincipal Investigator/Physician-Scientist, Massachusetts General Hospital; Assistant ProfessorVerified email at mgh.harvard.edu
