Calorie restriction-induced SIRT6 activation delays aging by suppressing NF-κB signaling N Zhang, Z Li, W Mu, L Li, Y Liang, M Lu, Z Wang, Y Qiu, Z Wang Cell cycle 15 (7), 1009-1018, 2016 | 127 | 2016 |
A membrane transporter is required for steroid hormone uptake in Drosophila N Okamoto, R Viswanatha, R Bittar, Z Li, S Haga-Yamanaka, N Perrimon, ... Developmental cell 47 (3), 294-305. e7, 2018 | 122 | 2018 |
Overexpressed SIRT6 attenuates cisplatin-induced acute kidney injury by inhibiting ERK1/2 signaling Z Li, K Xu, N Zhang, G Amador, Y Wang, S Zhao, L Li, Y Qiu, Z Wang Kidney international 93 (4), 881-892, 2018 | 91 | 2018 |
Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in Drosophila cells R Viswanatha, Z Li, Y Hu, N Perrimon Elife 7, e36333, 2018 | 73 | 2018 |
Resveratrol protects against high-fat diet induced renal pathological damage and cell senescence by activating SIRT1 N Zhang, Z Li, K Xu, Y Wang, Z Wang Biological and Pharmaceutical Bulletin 39 (9), 1448-1454, 2016 | 35 | 2016 |
Aging kidney and aging-related disease Z Li, Z Wang Aging and Aging-Related Diseases: Mechanisms and Interventions, 169-187, 2018 | 28 | 2018 |
Metabolite activation of tumorigenic signaling pathways in the tumor microenvironment V Low, Z Li, J Blenis Science Signaling 15 (759), eabj4220, 2022 | 26 | 2022 |
Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Z Li, V Low, V Luga, J Sun, E Earlie, B Parang, K Shobana Ganesh, ... Nature communications 13 (1), 6239, 2022 | 26 | 2022 |
Protective effects of SIRT6 overexpression against DSS-induced colitis in mice K Xu, Y Guo, L Ping, Y Qiu, Q Liu, Z Li, Z Wang Cells 9 (6), 1513, 2020 | 26 | 2020 |
A high‐fat diet reverses metabolic disorders and premature aging by modulating insulin and IGF1 signaling in SIRT6 knockout mice Z Li, K Xu, Y Guo, L Ping, Y Gao, Y Qiu, J Ni, Q Liu, Z Wang Aging cell 19 (3), e13104, 2020 | 26 | 2020 |
Aging biomarkers and novel targets for anti-aging interventions K Xu, Y Guo, Z Li, Z Wang Reviews on Biomarker Studies in Aging and Anti-Aging Research, 39-56, 2019 | 26 | 2019 |
Suppression of nuclear GSK3 signaling promotes serine/one-carbon metabolism and confers metabolic vulnerability in lung cancer cells L He, J Endress, S Cho, Z Li, Y Zheng, JM Asara, J Blenis Science Advances 8 (20), eabm8786, 2022 | 20 | 2022 |
Decreased Enterobacteriaceae translocation due to gut microbiota remodeling mediates the alleviation of premature aging by a high‐fat diet K Xu, Y Guo, Y Wang, Y Ren, V Low, S Cho, L Ping, K Peng, X Li, Y Qiu, ... Aging Cell 22 (2), e13760, 2023 | 14 | 2023 |
Pooled CRISPR Screens in Drosophila Cells R Viswanatha, R Brathwaite, Y Hu, Z Li, J Rodiger, P Merckaert, V Chung, ... Current protocols in molecular biology 129 (1), e111, 2019 | 13 | 2019 |
Improved detection of synthetic lethal interactions in Drosophila cells using variable dose analysis (VDA) BE Housden, Z Li, C Kelley, Y Wang, Y Hu, AJ Valvezan, BD Manning, ... Proceedings of the National Academy of Sciences 114 (50), E10755-E10762, 2017 | 10 | 2017 |
SPATA4 improves aging‐induced metabolic dysfunction through promotion of preadipocyte differentiation and adipose tissue expansion Z Li, K Xu, S Zhao, Y Guo, H Chen, J Ni, Q Liu, Z Wang Aging cell 20 (1), e13282, 2021 | 8 | 2021 |
Methylmalonic acid in TME signaling V Low, Z Li, A Laughney, W Jin, N Dephoure, V Luga, E Earlie, B Parang, ... Cancer Research 82 (12_Supplement), 3175-3175, 2022 | | 2022 |
Methylmalonic acid is elevated in non-small cell lung cancer and promotes drug resistance B Parang, Z Li, V Low, J Endress, M Malbari, A Saxena, N Altorki, J Blenis Cancer Research 82 (12_Supplement), 2378-2378, 2022 | | 2022 |
Variable dose analysis: A novel RNAi-based method for detection of synthetic lethal interactions BE Housden, Z Li, C Kelley, Y Wang, Y Hu, AJ Valvezan, BD Manning, ... bioRxiv, 176974, 2017 | | 2017 |