| Crystal violet staining is a reliable alternative to bicinchoninic acid assay-based normalization J Nilles, J Weiss, D Theile Biotechniques 73 (3), 131-135, 2022 | 18 | 2022 |
| Regulation of pxr function by coactivator and corepressor proteins: Ligand binding is just the beginning JP Rigalli, D Theile, J Nilles, J Weiss Cells 10 (11), 3137, 2021 | 11 | 2021 |
| Comprehensive in vitro analysis evaluating the variable drug–drug interaction risk of rifampicin compared to rifabutin J Nilles, J Weiss, M Sauter, WE Haefeli, S Ruez, D Theile Archives of Toxicology 97 (8), 2219-2230, 2023 | 4 | 2023 |
| How to avoid misinterpretation of dual reporter gene assay data affected by cell damage J Nilles, J Weiss, WE Haefeli, S Ruez, D Theile Archives of Toxicology 96 (9), 2501-2510, 2022 | 4 | 2022 |
| Physiology‐based pharmacokinetic modelling and experimental data suggest that rifabutin alters dolutegravir kinetics by both P‐glycoprotein induction and concurrent inhibition D Theile, J Nilles, AD Meid British Journal of Clinical Pharmacology 89 (7), 2329-2331, 2023 | 2 | 2023 |
| The differences in drug disposition gene induction by rifampicin and rifabutin are unlikely due to different effects on important pregnane X receptor (NR1I2) splice … J Nilles, J Weiss, M Masin, C Tuffs, MJ Strowitzki, WE Haefeli, S Ruez, ... Naunyn-schmiedeberg's Archives of Pharmacology 397 (4), 2485-2496, 2024 | 1 | 2024 |
| Lack of CYP3A4 protein induction despite mRNA induction in primary hepatocytes exposed to rifabutin as a possible explanation for its low interaction risk in vivo J Nilles, D Theile, J Weiss, WE Haefeli, S Ruez Archives of Toxicology, 1-16, 2024 | | 2024 |
| Rifabutin but not rifampicin can partly out-balance P-glycoprotein induction by concurrent P-glycoprotein inhibition through high affinity binding to the inhibitory site L Phondeth, R Kamaraj, J Nilles, J Weiss, WE Haefeli, P Pávek, D Theile Archives of Toxicology 98 (1), 223-231, 2024 | | 2024 |
| Rifampicin induces CYP3A4 and ABCB1 more efficiently than rifabutin despite lower cell uptake and potency to activate pregnane x receptor in vitro J Nilles, J Weiss, WE Haefeli, T Ebner, S Ruez, D Theile NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 395 (SUPPL 1), S55-S55, 2022 | | 2022 |
