Plant phenolic volatiles inhibit quorum sensing in pectobacteria and reduce their virulence by potential binding to ExpI and ExpR proteins JR Joshi, N Khazanov, H Senderowitz, S Burdman, A Lipsky, I Yedidia Scientific Reports 6 (1), 38126, 2016 | 88 | 2016 |
Sliding of p53 along DNA can be modulated by its oligomeric state and by cross-talks between its constituent domains N Khazanov, Y Levy Journal of molecular biology 408 (2), 335-355, 2011 | 77 | 2011 |
Guaiacol as a drug candidate for treating adult polyglucosan body disease O Kakhlon, I Ferreira, LJ Solmesky, N Khazanov, A Lossos, R Alvarez, ... JCI insight 3 (17), 2018 | 38 | 2018 |
Challenging a paradigm: Theoretical calculations of the protonation state of the Cys25‐His159 catalytic diad in free papain M Shokhen, N Khazanov, A Albeck Proteins: Structure, Function, and Bioinformatics 77 (4), 916-926, 2009 | 36 | 2009 |
Asymmetric DNA-search dynamics by symmetric dimeric proteins N Khazanov, A Marcovitz, Y Levy Biochemistry 52 (32), 5335-5344, 2013 | 29 | 2013 |
The mechanism of papain inhibition by peptidyl aldehydes M Shokhen, N Khazanov, A Albeck Proteins: Structure, Function, and Bioinformatics 79 (3), 975-985, 2011 | 27 | 2011 |
Specific stabilization of CFTR by phosphatidylserine E Hildebrandt, N Khazanov, JC Kappes, Q Dai, H Senderowitz, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (2), 289-293, 2017 | 25 | 2017 |
Direct Binding of Salicylic Acid to Pectobacterium N-Acyl-Homoserine Lactone Synthase JR Joshi, N Khazanov, N Khadka, AO Charkowski, S Burdman, N Carmi, ... ACS Chemical Biology 15 (7), 1883-1891, 2020 | 22 | 2020 |
Hsp104 facilitates the endoplasmic‐reticulum–associated degradation of disease‐associated and aggregation‐prone substrates LM Doonan, CJ Guerriero, GM Preston, TM Buck, N Khazanov, EA Fisher, ... Protein Science 28 (7), 1290-1306, 2019 | 22 | 2019 |
Novel inhibitors of leukocyte transendothelial migration T Getter, R Margalit, S Kahremany, L Levy, E Blum, N Khazanov, ... Bioorganic chemistry 92, 103250, 2019 | 21 | 2019 |
Phloretin, an apple phytoalexin, affects the virulence and fitness of Pectobacterium brasiliense by interfering with quorum-sensing M Pun, N Khazanov, O Galsurker, M Weitman, Z Kerem, H Senderowitz, ... Frontiers in Plant Science 12, 671807, 2021 | 19 | 2021 |
Discovery and design of novel small molecule GSK-3 inhibitors targeting the substrate binding site I Rippin, N Khazanov, S Ben Joseph, T Kudinov, E Berent, ... International Journal of Molecular Sciences 21 (22), 8709, 2020 | 19 | 2020 |
Potentiators exert distinct effects on human, murine, and Xenopus CFTR G Cui, N Khazanov, BB Stauffer, DT Infield, BR Imhoff, H Senderowitz, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 311 (2 …, 2016 | 19 | 2016 |
Interkingdom signaling interference: the effect of plant-derived small molecules on quorum sensing in plant-pathogenic bacteria JR Joshi, N Khazanov, A Charkowski, A Faigenboim, H Senderowitz, ... Annual Review of Phytopathology 59, 153-190, 2021 | 18 | 2021 |
An ancient CFTR ortholog informs molecular evolution in ABC transporters G Cui, J Hong, YW Chung-Davidson, D Infield, X Xu, J Li, L Simhaev, ... Developmental cell 51 (4), 421-430. e3, 2019 | 18 | 2019 |
Structural stability of purified human CFTR is systematically improved by mutations in nucleotide binding domain 1 Z Yang, E Hildebrandt, F Jiang, AA Aleksandrov, N Khazanov, Q Zhou, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (5), 1193-1204, 2018 | 18 | 2018 |
A novel image-based high-throughput screening assay discovers therapeutic candidates for adult polyglucosan body disease LJ Solmesky, N Khazanov, H Senderowitz, P Wang, BA Minassian, ... Biochemical Journal 474 (20), 3403-3420, 2017 | 13 | 2017 |
Screening of the active site from water by the incoming ligand triggers catalysis and inhibition in serine proteases M Shokhen, N Khazanov, A Albeck Proteins: Structure, Function, and Bioinformatics 70 (4), 1578-1587, 2008 | 13 | 2008 |
Design of compact biomimetic cellulose binding peptides as carriers for cellulose catalytic degradation N Khazanov, T Iline-Vul, E Noy, G Goobes, H Senderowitz The Journal of Physical Chemistry B 120 (2), 309-319, 2016 | 12 | 2016 |
The cooperative effect between active site ionized groups and water desolvation controls the alteration of acid/base catalysis in serine proteases M Shokhen, N Khazanov, A Albeck ChemBioChem 8 (12), 1416-1421, 2007 | 12 | 2007 |