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Bo Shan
Bo Shan
Principal Investigator, Zhejiang University Institute of Translational Medicine
Verified email at zju.edu.cn - Homepage
Title
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Cited by
Year
The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity
B Shan, X Wang, Y Wu, C Xu, Z Xia, J Dai, M Shao, F Zhao, S He, L Yang, ...
Nature immunology 18 (5), 519-529, 2017
3102017
Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice
C Hepler, B Shan, Q Zhang, GH Henry, M Shao, L Vishvanath, ...
Elife 7, e39636, 2018
2692018
Fibroblast Growth Factor 21 Is Regulated by the IRE1α-XBP1 Branch of the Unfolded Protein Response and Counteracts Endoplasmic Reticulum Stress-induced Hepatic Steatosis*♦
S Jiang, C Yan, Q Fang, Y Zhang, Y Liu, Y Deng, B Shan, J Liu, H Li, ...
Journal of Biological Chemistry 289 (43), 29751-29765, 2014
2102014
Hepatic IRE1α regulates fasting-induced metabolic adaptive programs through the XBP1s–PPARα axis signalling
M Shao, B Shan, Y Liu, Y Deng, C Yan, Y Wu, T Mao, Y Qiu, Y Zhou, ...
Nature communications 5 (1), 3528, 2014
1452014
De novo adipocyte differentiation from Pdgfrβ+ preadipocytes protects against pathologic visceral adipose expansion in obesity
M Shao, L Vishvanath, NC Busbuso, C Hepler, B Shan, AX Sharma, ...
Nature Communications 9 (1), 890, 2018
1402018
Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity
M Shao, C Hepler, Q Zhang, B Shan, L Vishvanath, GH Henry, S Zhao, ...
Cell Stem Cell 28 (4), 685-701. e7, 2021
682021
Perivascular mesenchymal cells control adipose-tissue macrophage accrual in obesity
B Shan, M Shao, Q Zhang, C Hepler, VA Paschoal, SD Barnes, ...
Nature metabolism 2 (11), 1332-1349, 2020
602020
Dual role for inositol‐requiring enzyme 1α in promoting the development of hepatocellular carcinoma during diet‐induced obesity in mice
Y Wu, B Shan, J Dai, Z Xia, J Cai, T Chen, S Lv, Y Feng, L Zheng, Y Wang, ...
Hepatology 68 (2), 533-546, 2018
592018
Adiponectin preserves metabolic fitness during aging
N Li, S Zhao, Z Zhang, Y Zhu, CM Gliniak, L Vishvanath, YA An, M Wang, ...
Elife 10, e65108, 2021
482021
The mitochondrial dicarboxylate carrier prevents hepatic lipotoxicity by inhibiting white adipocyte lipolysis
YA An, S Chen, Y Deng, ZV Wang, JB Funcke, M Shah, B Shan, ...
Journal of hepatology 75 (2), 387-399, 2021
372021
Multilayered omics reveal sex-and depot-dependent adipose progenitor cell heterogeneity
B Shan, CS Barker, M Shao, Q Zhang, RK Gupta, Y Wu
Cell metabolism 34 (5), 783-799. e7, 2022
302022
Adipocyte IRE1α promotes PGC1α mRNA decay and restrains adaptive thermogenesis
Y Chen, Z Wu, S Huang, X Wang, S He, L Liu, Y Hu, L Chen, P Chen, ...
Nature metabolism 4 (9), 1166-1184, 2022
192022
Cold-responsive adipocyte progenitors couple adrenergic signaling to immune cell activation to promote beige adipocyte accrual
B Shan, M Shao, Q Zhang, YA An, L Vishvanath, RK Gupta
Genes & Development 35 (19-20), 1333-1338, 2021
182021
ZFP423 controls EBF2 coactivator recruitment and PPARγ occupancy to determine the thermogenic plasticity of adipocytes
M Shao, Q Zhang, A Truong, B Shan, L Vishvanath, L Li, P Seale, ...
Genes & development 35 (21-22), 1461-1474, 2021
172021
Adipose tissue macrophage in immune regulation of metabolism
Y Qiu, B Shan, L Yang, Y Liu
Science China Life Sciences 59, 1232-1240, 2016
162016
The ER stress sensor inositol-requiring enzyme 1α in Kupffer cells promotes hepatic ischemia-reperfusion injury
J Cai, X Zhang, P Chen, Y Li, S Liu, Q Liu, H Zhang, Z Wu, K Song, J Liu, ...
Journal of Biological Chemistry 298 (1), 2022
132022
Distinct functional properties of murine perinatal and adult adipose progenitor subpopulations
Q Zhang, B Shan, L Guo, M Shao, L Vishvanath, G Elmquist, L Xu, ...
Nature metabolism 4 (8), 1055-1070, 2022
102022
Isolation of adipogenic and fibro-inflammatory stromal cell subpopulations from murine intra-abdominal adipose depots
J Peics, L Vishvanath, Q Zhang, B Shan, TÅ Pedersen, RK Gupta
JoVE (Journal of Visualized Experiments), e61610, 2020
82020
Protocol for quantitative proteomic analysis of heterogeneous adipose tissue-residing progenitor subpopulations in mice
B Shan, CS Barker, H Theraulaz, X Zhang, Y Ping, RK Gupta, M Shao, ...
STAR protocols 4 (4), 102676, 2023
12023
Hepatic IRE1α-XBP1 signaling promotes GDF15-mediated anorexia and body weight loss in chemotherapy
Y Tang, T Yao, X Tian, X Xia, X Huang, Z Qin, Z Shen, L Zhao, Y Zhao, ...
Journal of Experimental Medicine 221 (7), 2024
2024
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