Rapamycin fed late in life extends lifespan in genetically heterogeneous mice DE Harrison, R Strong, ZD Sharp, JF Nelson, CM Astle, K Flurkey, ... nature 460 (7253), 392, 2009 | 4110 | 2009 |
Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice RA Miller, DE Harrison, CM Astle, JA Baur, AR Boyd, R De Cabo, ... The Journals of Gerontology: Series A 66 (2), 191-201, 2011 | 962 | 2011 |
Rapamycin‐mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction RA Miller, DE Harrison, CM Astle, E Fernandez, K Flurkey, M Han, ... Aging cell 13 (3), 468-477, 2014 | 576 | 2014 |
Acarbose, 17‐α‐estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males DE Harrison, R Strong, DB Allison, BN Ames, CM Astle, H Atamna, ... Aging cell 13 (2), 273-282, 2014 | 384 | 2014 |
Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer R Strong, RA Miller, A Antebi, CM Astle, M Bogue, MS Denzel, ... Aging Cell 15 (5), 872-884, 2016 | 319 | 2016 |
Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice R Strong, RA Miller, CM Astle, JA Baur, R De Cabo, E Fernandez, W Guo, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2012 | 236 | 2012 |
WIN55, 212‐2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine mouse model of Parkinson’s disease DA Price, AA Martinez, A Seillier, W Koek, Y Acosta, E Fernandez, ... European Journal of Neuroscience 29 (11), 2177-2186, 2009 | 230 | 2009 |
Neurodegeneration and motor dysfunction in mice lacking cytosolic and mitochondrial aldehyde dehydrogenases: implications for Parkinson's disease MCY Wey, E Fernandez, PA Martinez, P Sullivan, DS Goldstein, R Strong PLoS One 7 (2), e31522, 2012 | 158 | 2012 |
Rapamycin-induced metabolic defects are reversible in both lean and obese mice Y Liu, V Diaz, E Fernandez, R Strong, L Ye, JA Baur, DW Lamming, ... Aging (Albany NY) 6 (9), 742, 2014 | 69 | 2014 |
Rapamycin improves motor function, reduces 4-hydroxynonenal adducted protein in brain, and attenuates synaptic injury in a mouse model of synucleinopathy X Bai, MCY Wey, E Fernandez, MJ Hart, J Gelfond, AF Bokov, S Rani, ... Pathobiology of Aging & Age-related Diseases 5 (1), 28743, 2015 | 67 | 2015 |
Testing efficacy of administration of the antiaging drug rapamycin in a nonhuman primate, the common marmoset S Tardif, C Ross, P Bergman, E Fernandez, M Javors, A Salmon, J Spross, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2014 | 60 | 2014 |
Metabolic consequences of long-term rapamycin exposure on common marmoset monkeys (Callithrix jacchus) C Ross, A Salmon, R Strong, E Fernandez, M Javors, A Richardson, ... Aging (Albany NY) 7 (11), 964, 2015 | 51 | 2015 |
Interaction of a glucocorticoid‐responsive element with regulatory sequences in the promoter region of the mouse tyrosine hydroxylase gene T Hagerty, E Fernandez, K Lynch, SS Wang, WW Morgan, R Strong Journal of neurochemistry 78 (6), 1379-1388, 2001 | 50 | 2001 |
Protection against noise-induced hearing loss in young CBA/J mice by low-dose kanamycin EA Fernandez, KK Ohlemiller, PM Gagnon, WW Clark Journal of the Association for Research in Otolaryngology 11 (2), 235-244, 2010 | 39 | 2010 |
Metformin reduces glucose intolerance caused by rapamycin treatment in genetically heterogeneous female mice. R Weiss, E Fernandez, Y Liu, R Strong, AB Salmon Aging, 2018 | 36 | 2018 |
Transcriptional and post-transcriptional regulation of tyrosine hydroxylase messenger RNA in PC12 cells during persistent stimulation by VIP and PACAP38: differential … J Corbitt, T Hagerty, E Fernandez, WW Morgan, R Strong Neuropeptides 36 (1), 34-45, 2002 | 33 | 2002 |
Protein Synthesis Blockade Differentially Affects the Degradation of Constitutive and Nicotinic Receptor‐Induced Tyrosine Hydroxylase Protein Level in Isolated Bovine … E Fernandez, GL Craviso Journal of neurochemistry 73 (1), 169-178, 1999 | 29 | 1999 |
Monoamine metabolism and behavioral responses to ethanol in mitochondrial aldehyde dehydrogenase knockout mice E Fernandez, W Koek, Q Ran, GA Gerhardt, CP France, R Strong Alcoholism: Clinical and Experimental Research 30 (10), 1650-1658, 2006 | 25 | 2006 |
WIN55, 212-2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the MPTP mouse model of Parkinson’s disease DA Price, AA Martinez, A Seillier, W Koek, Y Acosta, E Fernandez, ... The European journal of neuroscience 29 (11), 2177, 2009 | 14 | 2009 |
Effects of anabolic androgenic steroids and social subjugation on behavior and neurochemistry in male rats KA Frahm, AR Lumia, E Fernandez, R Strong, JL Roberts, MY McGinnis Pharmacology Biochemistry and Behavior 97 (3), 416-422, 2011 | 12 | 2011 |