Hypoxia-induced exosomes contribute to a more aggressive and chemoresistant ovarian cancer phenotype: a novel mechanism linking STAT3/Rab proteins KDP Dorayappan, R Wanner, JJ Wallbillich, U Saini, R Zingarelli, ... Oncogene 37 (28), 3806-3821, 2018 | 245 | 2018 |
A microfluidic chip enables isolation of exosomes and establishment of their protein profiles and associated signaling pathways in ovarian cancer KDP Dorayappan, ML Gardner, CL Hisey, RA Zingarelli, BQ Smith, ... Cancer research 79 (13), 3503-3513, 2019 | 85 | 2019 |
High glucose-mediated STAT3 activation in endometrial cancer is inhibited by metformin: therapeutic implications for endometrial cancer JJ Wallbillich, S Josyula, U Saini, RA Zingarelli, KDP Dorayappan, ... PLoS One 12 (1), e0170318, 2017 | 48 | 2017 |
MAX Mutations in Endometrial Cancer: Clinicopathologic Associations and Recurrent MAX p.His28Arg Functional Characterization CJ Walker, CM Rush, P Dama, MJ O’Hern, CM Cosgrove, JL Gillespie, ... JNCI: Journal of the National Cancer Institute 110 (5), 517-526, 2018 | 12 | 2018 |
Hypoxia-facilitated exosomal release from ovarian cancer cells is regulated by STAT3 and is associated with increased metastatic tumor burden KDP Dorayappan, JJ Wallbillich, U Saini, K Bixel, MK Riley, RA Zingarelli, ... Gynecologic oncology 141, 66, 2016 | 3 | 2016 |
Aberrant TMEM205-CD1B signaling promotes platinum resistance in ovarian cancer BQ Smith, U Saini, KDP Dorayappan, MK Riley, RA Zingarelli, R Wanner, ... Gynecologic Oncology 149, 65, 2018 | 2 | 2018 |
Exploring the role of obesity-induced exosome secretion and associated proteins in endometrial cancer pathogenesis: A roadmap for prevention through exosome inhibition T Sakaue, KDP Dorayappan, R Zingarelli, W Khadraoui, M Anbalagan, ... Cancer Research 84 (6_Supplement), 3377-3377, 2024 | | 2024 |
Exploring the role of obesity-induced extracellular vesicles secretion and associated oncogenic proteins in endometrial cancer pathogenesis. K Selvendiran, T Sakaue, R Zingarelli, KDP Dorayappan, W Khadraoui, ... | | 2024 |
Obesity-associated endometrial cancer: Identifying the contributions of TMEM205 expression to the pathogenesis of disease T Sakaue, R Zingarelli, W Khadraoui, U Saini, J Wallbillich, ... Cancer Research 83 (7_Supplement), 4236-4236, 2023 | | 2023 |
Evaluating exosome proteins as biomarkers for the early detection of high-grade serous ovarian cancer KDP Dorayappan, RA Zingarelli, CL Hisey, BQ Smith, R Wanner, U Saini, ... Gynecologic Oncology 149, 71, 2018 | | 2018 |
Tmem 205-mediated cisplatin resistance in ovarian clear cell carcinoma (OCCC) is overcome by herpes simplex virus (oHSV)/cisplatin combination therapy U Saini, M Riley, KD Dorayappan, C Bolyard, B Kaur, R Zingarelli, ... Cancer Research 77 (13_Supplement), 5888-5888, 2017 | | 2017 |
Exosomal oncogenic proteins promote tumor progression, metastasis and chemoresistance in ovarian cancer KDP Dorayappan, RA Wanner, RA Zingarelli, U Saini, S Karuppaiyah, ... Cancer Research 77 (13_Supplement), 5798-5798, 2017 | | 2017 |