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Hannah Gaunt
Hannah Gaunt
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Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance
B Rode, J Shi, N Endesh, MJ Drinkhill, PJ Webster, SJ Lotteau, MA Bailey, ...
Nature communications 8 (1), 350, 2017
2432017
(−)‐Englerin A is a potent and selective activator of TRPC4 and TRPC5 calcium channels
Y Akbulut, HJ Gaunt, K Muraki, MJ Ludlow, MS Amer, A Bruns, ...
Angewandte Chemie International Edition 54 (12), 3787-3791, 2015
2042015
Yoda1 analogue (D ooku1) which antagonizes Y oda1‐evoked activation of P iezo1 and aortic relaxation
EL Evans, K Cuthbertson, N Endesh, B Rode, NM Blythe, AJ Hyman, ...
British journal of pharmacology 175 (10), 1744-1759, 2018
1622018
Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels
HN Rubaiy, MJ Ludlow, M Henrot, HJ Gaunt, K Miteva, SY Cheung, ...
Journal of Biological Chemistry 292 (20), 8158-8173, 2017
952017
Piezo1 channels are mechanosensors in human fetoplacental endothelial cells
LC Morley, J Shi, HJ Gaunt, AJ Hyman, PJ Webster, C Williams, K Forbes, ...
MHR: Basic science of reproductive medicine 24 (10), 510-520, 2018
612018
(−)-Englerin A-evoked cytotoxicity is mediated by Na+ influx and counteracted by Na+/K+-ATPase
MJ Ludlow, HJ Gaunt, HN Rubaiy, KE Musialowski, NM Blythe, ...
Journal of Biological Chemistry 292 (2), 723-731, 2017
512017
Natural and synthetic flavonoid modulation of TRPC5 channels
J Naylor, A Minard, HJ Gaunt, MS Amer, LA Wilson, M Migliore, ...
British journal of pharmacology 173 (3), 562-574, 2016
512016
Transient receptor potential canonical 4 and 5 proteins as targets in cancer therapeutics
HJ Gaunt, NS Vasudev, DJ Beech
European Biophysics Journal 45, 611-620, 2016
462016
Rab46 integrates Ca2+ and histamine signaling to regulate selective cargo release from Weibel-Palade bodies
KT Miteva, L Pedicini, LA Wilson, I Jayasinghe, RG Slip, K Marszalek, ...
Journal of Cell Biology 218 (7), 2232-2246, 2019
362019
PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing
E Chuntharpursat-Bon, OV Povstyan, MJ Ludlow, DJ Carrier, M Debant, ...
Communications Biology 6 (1), 358, 2023
262023
AZD1775 induces toxicity through double-stranded DNA breaks independently of chemotherapeutic agents in p53-mutated colorectal cancer cells
PJ Webster, AT Littlejohns, HJ Gaunt, KR Prasad, DJ Beech, DA Burke
Cell Cycle 16 (22), 2176-2182, 2017
262017
Upregulated WEE1 protects endothelial cells of colorectal cancer liver metastases
PJ Webster, AT Littlejohns, HJ Gaunt, RS Young, B Rode, JE Ritchie, ...
Oncotarget 8 (26), 42288, 2017
122017
Homotypic endothelial nanotubes induced by wheat germ agglutinin and thrombin
L Pedicini, KT Miteva, V Hawley, HJ Gaunt, HL Appleby, RM Cubbon, ...
Scientific reports 8 (1), 7569, 2018
102018
Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance. Nat Commun 8 (1): 350
B Rode, J Shi, N Endesh, MJ Drinkhill, PJ Webster, SJ Lotteau, MA Bailey, ...
102017
Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance. Nat Commun. 2017; 8: 350
B Rode, J Shi, N Endesh, MJ Drinkhill, PJ Webster, SJ Lotteau, MA Bailey, ...
S41467-017-00429-3.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
8
Cell adhesion molecule interaction with Piezo1 channels is a mechanism for sub cellular regulation of mechanical sensitivity
E Chuntharpursat-Bon, OV Povstyan, MJ Ludlow, HJ Gaunt, PD Baxter, ...
bioRxiv, 602532, 2019
72019
Resistance of store‐operated calcium entry to tumour microenvironment conditions and enhanced potency of Synta66 in colorectal adenocarcinoma cells (1057.4)
H Appleby, H Gaunt, S Jansz, A Hyman, O Stokes, R Young, R Foster, ...
The FASEB Journal 28, 1057.4, 2014
12014
PIEZO1 force sensing controls global lipid homeostasis
L Lichtenstein, CW Cheng, EL Evans, HJ Gaunt, F Bartoli, ...
bioRxiv, 2023.07. 23.550198, 2023
2023
Nitric oxide synthase phosphorylation in fetoplacental endothelium is enhanced by agonism of Piezo1 mechanosensor in small for gestational age babies
LC Morley, M Debant, HJ Gaunt, NAB Simpson, DJ Beech
Reproduction and Fertility 4 (1), 2023
2023
PIEZO1 MECHANOSENSITIVE ION CHANNELS ARE REQUIRED FOR SHEAR STRESS SENSING IN PLACENTAL VASCULATURE
L Morley, J Shi, H Gaunt, A Hyman, P Webster, K Forbes, J Walker, ...
Placenta, 2018
2018
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