The role of oxidative stress in hyperuricemia and xanthine oxidoreductase (XOR) inhibitors N Liu, H Xu, Q Sun, X Yu, W Chen, H Wei, J Jiang, Y Xu, W Lu Oxidative Medicine and Cellular Longevity 2021 (1), 1470380, 2021 | 160 | 2021 |
¹H NMR-based metabolic profiling of human rectal cancer tissue H Wang, L Wang, H Zhang, P Deng, J Chen, B Zhou, J Hu, J Zou, W Lu, ... Molecular cancer 12, 1-12, 2013 | 111 | 2013 |
Taurine attenuates methamphetamine-induced autophagy and apoptosis in PC12 cells through mTOR signaling pathway Y Li, Z Hu, B Chen, Q Bu, W Lu, Y Deng, R Zhu, X Shao, J Hou, J Zhao, ... Toxicology letters 215 (1), 1-7, 2012 | 101 | 2012 |
Uric acid produces an inflammatory response through activation of NF-κB in the hypothalamus: implications for the pathogenesis of metabolic disorders W Lu, Y Xu, X Shao, F Gao, Y Li, J Hu, Z Zuo, X Shao, L Zhou, Y Zhao, ... Scientific reports 5 (1), 12144, 2015 | 99 | 2015 |
1H-NMR based metabonomic profiling of human esophageal cancer tissue L Wang, J Chen, L Chen, P Deng, Q Bu, P Xiang, M Li, W Lu, Y Xu, H Lin, ... Molecular cancer 12, 1-14, 2013 | 96 | 2013 |
Uric acid induces cognitive dysfunction through hippocampal inflammation in rodents and humans X Shao, W Lu, F Gao, D Li, J Hu, Y Li, Z Zuo, H Jie, Y Zhao, X Cen Journal of Neuroscience 36 (43), 10990-11005, 2016 | 62 | 2016 |
Activation of SREBP-1c alters lipogenesis and promotes tumor growth and metastasis in gastric cancer Q Sun, X Yu, C Peng, N Liu, W Chen, H Xu, H Wei, K Fang, Z Dong, C Fu, ... Biomedicine & Pharmacotherapy 128, 110274, 2020 | 52 | 2020 |
Chloroquine potentiates the anticancer effect of sunitinib on renal cell carcinoma by inhibiting autophagy and inducing apoptosis ML Li, YZ Xu, WJ Lu, YH Li, SS Tan, HJ Lin, TM Wu, Y Li, SY Wang, ... Oncology letters 15 (3), 2839-2846, 2018 | 37 | 2018 |
Hyperuricemia induces lipid disturbances mediated by LPCAT3 upregulation in the liver N Liu, Q Sun, H Xu, X Yu, W Chen, H Wei, J Jiang, Y Xu, W Lu The FASEB Journal, doi: 10.1096/fj.202000950R. Online ahead, 2020 | 31 | 2020 |
YL529, a novel, orally available multikinase inhibitor, potently inhibits angiogenesis and tumour growth in preclinical models Y Xu, H Lin, N Meng, W Lu, G Li, Y Han, X Dai, Y Xia, X Song, S Yang, ... British journal of pharmacology 169 (8), 1766-1780, 2013 | 20 | 2013 |
Hyperuricemia induces liver injury by upregulating HIF-1α and inhibiting arginine biosynthesis pathway in mouse liver and human L02 hepatocytes L Huang, X He, W Peng, X He, B Xu, H Xu, Y Wang, W Xu, W Chen, ... Biochemical and Biophysical Research Communications 617, 55-61, 2022 | 15 | 2022 |
# 2714, a novel active inhibitor with potent G2/M phase arrest and antitumor efficacy in preclinical models WJ Lu, W Peng, QQ Sun, YH Li, B Chen, LT Yu, YZ Xu, SY Wang, ... Cell death discovery 4 (1), 24, 2018 | 14 | 2018 |
Palmitic acid inhibits the growth and metastasis of gastric cancer by blocking the STAT3 signaling pathway X Yu, W Peng, Y Wang, W Xu, W Chen, L Huang, H Xu, X He, S Wang, ... Cancers 15 (2), 388, 2023 | 9 | 2023 |
YL4073 is a potent autophagy-stimulating antitumor agent in an in vivo model of Lewis lung carcinoma YZ Xu, YH Li, WJ Lu, K Lu, CT Wang, Y Li, HJ Lin, LX Kan, SY Yang, ... Oncology Reports 35 (4), 2081-2088, 2016 | 7 | 2016 |
A small molecular agent YL529 inhibits VEGF-D-induced lymphangiogenesis and metastasis in preclinical tumor models in addition to its known antitumor activities Y Xu, W Lu, P Yang, W Peng, C Wang, M Li, Y Li, G Li, N Meng, H Lin, ... BMc cancer 15, 1-12, 2015 | 7 | 2015 |
Emerging technologies, recent developments, and novel applications for drug metabolite identification W Lu, Y Xu, Y Zhao, X Cen Current Drug Metabolism 15 (9), 865-874, 2014 | 5 | 2014 |
Phosphatidylserine decarboxylase downregulation in uric acid‑induced hepatic mitochondrial dysfunction and apoptosis N Liu, L Huang, H Xu, X He, X He, J Cao, W Xu, Y Wang, H Wei, S Wang, ... MedComm 4 (4), e336, 2023 | 3 | 2023 |
Phosphoethanolamine cytidylyltransferase ameliorates mitochondrial function and apoptosis in hepatocytes in T2DM in vitro H Xu, W Li, L Huang, X He, B Xu, X He, W Chen, Y Wang, W Xu, S Wang, ... Journal of Lipid Research 64 (3), 2023 | 3 | 2023 |
Novel agent# 2714 potently inhibits lung cancer growth by suppressing cell proliferation and by inducing apoptosis in vitro and in vivo W Lu, Q Sun, B Chen, Y Li, Y Xu, S Wang Molecular Medicine Reports 19 (6), 4788-4796, 2019 | 2 | 2019 |
Mechanism of YJKL Decoction in Treating of PCOS Infertility by Integrative Approach of Network Pharmacology and Experimental Verification R Zhang, W Xu, H Wei, B Li, Y Wang, X He, J Cao, X He, M Xu, W Lu, ... Drug Design, Development and Therapy, 3853-3870, 2024 | | 2024 |