Liver-specific ablation of insulin-degrading enzyme causes hepatic insulin resistance and glucose intolerance, without affecting insulin clearance in mice P Villa-Pérez, B Merino, CM Fernández-Díaz, P Cidad, CD Lobatón, ... Metabolism 88, 1-11, 2018 | 59 | 2018 |
Chlorogenic acid/chromium supplement rescues diet-induced insulin resistance and obesity in mice HE Ghadieh, ZN Smiley, MW Kopfman, MG Najjar, MJ Hake, SM Najjar Nutrition & metabolism 12, 1-7, 2015 | 55 | 2015 |
Loss of hepatic CEACAM1: a unifying mechanism linking insulin resistance to obesity and non-alcoholic fatty liver disease G Heinrich, HE Ghadieh, SS Ghanem, HT Muturi, K Rezaei, QY Al-Share, ... Frontiers in endocrinology 8, 8, 2017 | 43 | 2017 |
Hyperinsulinemia drives hepatic insulin resistance in male mice with liver-specific Ceacam1 deletion independently of lipolysis HE Ghadieh, L Russo, HT Muturi, SS Ghanem, IH Manaserh, HL Noh, ... Metabolism 93, 33-43, 2019 | 40 | 2019 |
Liver-specific reconstitution of CEACAM1 reverses the metabolic abnormalities caused by its global deletion in male mice L Russo, HT Muturi, HE Ghadieh, SS Ghanem, TA Bowman, HL Noh, ... Diabetologia 60 (12), 2463-2474, 2017 | 36 | 2017 |
Reduced hepatic carcinoembryonic antigen-related cell adhesion molecule 1 level in obesity G Heinrich, HT Muturi, K Rezaei, QY Al-Share, AM DeAngelis, ... Frontiers in endocrinology 8, 54, 2017 | 27 | 2017 |
High-fat diet amplifies renal renin angiotensin system expression, blood pressure elevation, and renal dysfunction caused by Ceacam1 null deletion C Li, SA Culver, S Quadri, KL Ledford, QY Al-Share, HE Ghadieh, ... American Journal of Physiology-Endocrinology and Metabolism 309 (9), E802-E810, 2015 | 25 | 2015 |
Exenatide induces carcinoembryonic antigen‐related cell adhesion molecule 1 expression to prevent hepatic steatosis HE Ghadieh, HT Muturi, L Russo, CC Marino, SS Ghanem, SS Khuder, ... Hepatology communications 2 (1), 35-47, 2018 | 21 | 2018 |
Role for hepatic CEACAM1 in regulating fatty acid metabolism along the adipocyte-hepatocyte axis [S] L Russo, HE Ghadieh, SS Ghanem, QY Al-Share, ZN Smiley, ... Journal of lipid research 57 (12), 2163-2175, 2016 | 20 | 2016 |
Liver-specific rescuing of CEACAM1 reverses endothelial and cardiovascular abnormalities in male mice with null deletion of Ceacam1 gene L Russo, HT Muturi, HE Ghadieh, AM Wisniewski, EE Morgan, SS Quadri, ... Molecular metabolism 9, 98-113, 2018 | 17 | 2018 |
Leptin resistance contributes to obesity in mice with null mutation of carcinoembryonic antigen-related cell adhesion molecule 1 G Heinrich, L Russo, TR Castaneda, V Pfeiffer, HE Ghadieh, SS Ghanem, ... Journal of Biological Chemistry 291 (21), 11124-11132, 2016 | 17 | 2016 |
Reno-protective effect of GLP-1 receptor agonists in Type1 diabetes: dual action on TRPC6 and NADPH oxidases N Youssef, M Noureldein, R Njeim, HE Ghadieh, F Harb, ST Azar, N Fares, ... Biomedicines 9 (10), 1360, 2021 | 15 | 2021 |
Exenatide prevents diet-induced hepatocellular injury in a CEACAM1-dependent mechanism HE Ghadieh, HT Muturi, SM Najjar Journal of diabetes and treatment 2017 (4), 2017 | 10 | 2017 |
Regulation of hepatic fibrosis by carcinoembryonic antigen-related cell adhesion molecule 1 RA Helal, L Russo, HE Ghadieh, HT Muturi, S Asalla, AD Lee, ... Metabolism 121, 154801, 2021 | 9 | 2021 |
CYP450 mediates reactive oxygen species production in a mouse model of β-thalassemia through an increase in 20-HETE activity R Bou-Fakhredin, B Dia, HE Ghadieh, S Rivella, MD Cappellini, AA Eid, ... International Journal of Molecular Sciences 22 (3), 1106, 2021 | 8 | 2021 |
Loss of Ceacam1 promotes prostate cancer progression in Pten haploinsufficient male mice J Liu, HT Muturi, SS Khuder, RA Helal, HE Ghadieh, SK Ramakrishnan, ... Metabolism 107, 154215, 2020 | 7 | 2020 |
Regulation of insulin clearance by non-esterified fatty acids SM Najjar, R Abdolahipour, HE Ghadieh, MS Jahromi, JA Najjar, ... Biomedicines 10 (8), 1899, 2022 | 6 | 2022 |
Insulin sensitivity is retained in mice with endothelial loss of carcinoembryonic antigen cell adhesion molecule 1 HT Muturi, SS Khuder, HE Ghadieh, EL Esakov, H Noh, H Kang, ... Cells 10 (8), 2093, 2021 | 6 | 2021 |
VEGF-A: a novel mechanistic link between CYP2C-derived EETs and Nox4 in diabetic kidney disease R Njeim, K Braych, HE Ghadieh, NS Azar, WS Azar, B Dia, A Leone, ... Diabetes 72 (7), 947-957, 2023 | 5 | 2023 |
Translational aspects of the mammalian target of rapamycin complexes in diabetic nephropathy A Abou Daher, S Alkhansa, WS Azar, R Rafeh, HE Ghadieh, AA Eid Antioxidants & Redox Signaling 37 (10-12), 802-819, 2022 | 5 | 2022 |