Gene expression signatures identify novel therapeutics for metastatic pancreatic neuroendocrine tumors AT Scott, M Weitz, PJ Breheny, PH Ear, B Darbro, BJ Brown, TA Braun, ... Clinical cancer research 26 (8), 2011-2021, 2020 | 44 | 2020 |
Pancreatic neuroendocrine tumors: molecular mechanisms and therapeutic targets CK Maharjan, PH Ear, CG Tran, JR Howe, C Chandrasekharan, ... Cancers 13 (20), 5117, 2021 | 38 | 2021 |
RABL6A is an essential driver of MPNSTs that negatively regulates the RB1 pathway and sensitizes tumor cells to CDK4/6 inhibitors JL Kohlmeyer, CA Kaemmer, C Pulliam, CK Maharjan, AM Samayoa, ... Clinical cancer research 26 (12), 2997-3011, 2020 | 34 | 2020 |
Natural and synthetic estrogens in chronic inflammation and breast cancer CK Maharjan, J Mo, L Wang, MC Kim, S Wang, N Borcherding, P Vikas, ... Cancers 14 (1), 206, 2021 | 11 | 2021 |
Breast cancer stem cells: Signaling pathways, cellular interactions, and therapeutic implications L Wang, Z Jin, RP Master, CK Maharjan, ME Carelock, TBA Reccoppa, ... Cancers 14 (13), 3287, 2022 | 10 | 2022 |
RABL6A promotes pancreatic neuroendocrine tumor angiogenesis and progression in vivo CK Maharjan, S Umesalma, CA Kaemmer, VP Muniz, C Bauchle, SL Mott, ... Biomedicines 9 (6), 633, 2021 | 7 | 2021 |
Development and comparison of novel bioluminescent mouse models of pancreatic neuroendocrine neoplasm metastasis CA Kaemmer, S Umesalma, CK Maharjan, DL Moose, G Narla, SL Mott, ... Scientific reports 11 (1), 10252, 2021 | 4 | 2021 |
Targeting intracellular proteins with cell type-specific functions for cancer immunotherapy ME Carelock, RP Master, MC Kim, Z Jin, L Wang, CK Maharjan, N Hua, ... Life Medicine 2 (3), lnad019, 2023 | 3 | 2023 |
Epithelial IL-2 is critical for NK cell-mediated cancer immunosurveillance in mammary glands L Wang, CK Maharjan, N Borcherding, RP Master, J Mo, TI Tithi, MC Kim, ... bioRxiv, 2024.04. 25.591178, 2024 | | 2024 |
PROTAC-mediated NR4A1 degradation as a novel strategy for cancer immunotherapy L Wang, Y Xiao, Y Luo, RP Master, J Mo, MC Kim, Y Liu, CK Maharjan, ... Journal of Experimental Medicine 221 (3), e20231519, 2024 | | 2024 |
Therapies targeting CDK4/6 cause regression, immune cell activation, and sensitization to PD-L1 immunotherapy in pancreatic neuroendocrine tumors C Kaemmer, S Umesalma, C Maharjan, J Kohlmeyer, J Lingo, ... Endocrine Abstracts 98, 2023 | | 2023 |
CDK4/6-MEK Targeted Therapy Causes Regression and Reduced Metastatic Colonization of Pancreatic Neuroendocrine Tumors C Kaemmer, S Umesalma, C Maharjan, J Kohlmeyer, E Wilkerson, ... Endocrine Abstracts 89, 2023 | | 2023 |
RABL6A-Myc Signaling Promotes Pancreatic Neuroendocrine Tumor Cell Proliferation and Survival U Shaikamjad, RM Sheehy, A Schab, C Kaemmer, CK Maharjan, S Bell, ... PANCREAS 51 (3), E32-E32, 2022 | | 2022 |
Functional Genetic Screen to Identify Drivers of Pancreatic Neuroendocrine Tumor Pathogenesis CK Maharjan, J Riordan, C Fedderson, E Zhu, B Darbro, A Dupuy, ... PANCREAS 50 (3), 444-444, 2021 | | 2021 |
Role of RABL6A in pancreatic neuroendocrine tumor development and progression CK Maharjan The University of Iowa, 2021 | | 2021 |
Efficacy of Combined MEK and CDK Targeted Therapies for Pancreatic Neuroendocrine Tumors S Umesalma, CA Kaemmer, CK Maharjan, JL Kohlmeyer, D Goldfard, ... PANCREAS 50 (3), 444-444, 2021 | | 2021 |
CDK-Targeted Combination Therapies of Pancreatic Neuroendocrine Tumors (PNETS) Guided by RABL6A-Dependent Regulation of the PNET Kinome and Phosphoproteome USS Amjad, C Kaemmer, CK Maharjan, J Kohlmeyer, L Herring, ... PANCREAS 49 (3), 486-487, 2020 | | 2020 |
RABL6A Promotes PNETAngiogenesis and Development In Vivo CK Maharjan, C Kaemmer, C Bauchle, S Stephens, D Meyerholz, ... PANCREAS 49 (3), 478-478, 2020 | | 2020 |
Novel Mouse Models of Pancreatic Neuroendocrine Tumor Metastasis C Kaemmer, U Shaik, CK Maharjan, D Moose, G Narla, B Darbro, ... PANCREAS 49 (3), 471-472, 2020 | | 2020 |
Differential Gene Expression in Metastatic Pancreatic Neuroendocrine Tumors Predicts Novel Therapeutic Agents A Scott, M Weitz, P Breheny, PH Ear, B Darbro, B Brown, T Braun, GY Li, ... PANCREAS 49 (3), 485-485, 2020 | | 2020 |