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Chandra K. Maharjan
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Gene expression signatures identify novel therapeutics for metastatic pancreatic neuroendocrine tumors
AT Scott, M Weitz, PJ Breheny, PH Ear, B Darbro, BJ Brown, TA Braun, ...
Clinical cancer research 26 (8), 2011-2021, 2020
442020
Pancreatic neuroendocrine tumors: molecular mechanisms and therapeutic targets
CK Maharjan, PH Ear, CG Tran, JR Howe, C Chandrasekharan, ...
Cancers 13 (20), 5117, 2021
382021
RABL6A is an essential driver of MPNSTs that negatively regulates the RB1 pathway and sensitizes tumor cells to CDK4/6 inhibitors
JL Kohlmeyer, CA Kaemmer, C Pulliam, CK Maharjan, AM Samayoa, ...
Clinical cancer research 26 (12), 2997-3011, 2020
342020
Natural and synthetic estrogens in chronic inflammation and breast cancer
CK Maharjan, J Mo, L Wang, MC Kim, S Wang, N Borcherding, P Vikas, ...
Cancers 14 (1), 206, 2021
112021
Breast cancer stem cells: Signaling pathways, cellular interactions, and therapeutic implications
L Wang, Z Jin, RP Master, CK Maharjan, ME Carelock, TBA Reccoppa, ...
Cancers 14 (13), 3287, 2022
102022
RABL6A promotes pancreatic neuroendocrine tumor angiogenesis and progression in vivo
CK Maharjan, S Umesalma, CA Kaemmer, VP Muniz, C Bauchle, SL Mott, ...
Biomedicines 9 (6), 633, 2021
72021
Development and comparison of novel bioluminescent mouse models of pancreatic neuroendocrine neoplasm metastasis
CA Kaemmer, S Umesalma, CK Maharjan, DL Moose, G Narla, SL Mott, ...
Scientific reports 11 (1), 10252, 2021
42021
Targeting intracellular proteins with cell type-specific functions for cancer immunotherapy
ME Carelock, RP Master, MC Kim, Z Jin, L Wang, CK Maharjan, N Hua, ...
Life Medicine 2 (3), lnad019, 2023
32023
Epithelial IL-2 is critical for NK cell-mediated cancer immunosurveillance in mammary glands
L Wang, CK Maharjan, N Borcherding, RP Master, J Mo, TI Tithi, MC Kim, ...
bioRxiv, 2024.04. 25.591178, 2024
2024
PROTAC-mediated NR4A1 degradation as a novel strategy for cancer immunotherapy
L Wang, Y Xiao, Y Luo, RP Master, J Mo, MC Kim, Y Liu, CK Maharjan, ...
Journal of Experimental Medicine 221 (3), e20231519, 2024
2024
Therapies targeting CDK4/6 cause regression, immune cell activation, and sensitization to PD-L1 immunotherapy in pancreatic neuroendocrine tumors
C Kaemmer, S Umesalma, C Maharjan, J Kohlmeyer, J Lingo, ...
Endocrine Abstracts 98, 2023
2023
CDK4/6-MEK Targeted Therapy Causes Regression and Reduced Metastatic Colonization of Pancreatic Neuroendocrine Tumors
C Kaemmer, S Umesalma, C Maharjan, J Kohlmeyer, E Wilkerson, ...
Endocrine Abstracts 89, 2023
2023
RABL6A-Myc Signaling Promotes Pancreatic Neuroendocrine Tumor Cell Proliferation and Survival
U Shaikamjad, RM Sheehy, A Schab, C Kaemmer, CK Maharjan, S Bell, ...
PANCREAS 51 (3), E32-E32, 2022
2022
Functional Genetic Screen to Identify Drivers of Pancreatic Neuroendocrine Tumor Pathogenesis
CK Maharjan, J Riordan, C Fedderson, E Zhu, B Darbro, A Dupuy, ...
PANCREAS 50 (3), 444-444, 2021
2021
Role of RABL6A in pancreatic neuroendocrine tumor development and progression
CK Maharjan
The University of Iowa, 2021
2021
Efficacy of Combined MEK and CDK Targeted Therapies for Pancreatic Neuroendocrine Tumors
S Umesalma, CA Kaemmer, CK Maharjan, JL Kohlmeyer, D Goldfard, ...
PANCREAS 50 (3), 444-444, 2021
2021
CDK-Targeted Combination Therapies of Pancreatic Neuroendocrine Tumors (PNETS) Guided by RABL6A-Dependent Regulation of the PNET Kinome and Phosphoproteome
USS Amjad, C Kaemmer, CK Maharjan, J Kohlmeyer, L Herring, ...
PANCREAS 49 (3), 486-487, 2020
2020
RABL6A Promotes PNETAngiogenesis and Development In Vivo
CK Maharjan, C Kaemmer, C Bauchle, S Stephens, D Meyerholz, ...
PANCREAS 49 (3), 478-478, 2020
2020
Novel Mouse Models of Pancreatic Neuroendocrine Tumor Metastasis
C Kaemmer, U Shaik, CK Maharjan, D Moose, G Narla, B Darbro, ...
PANCREAS 49 (3), 471-472, 2020
2020
Differential Gene Expression in Metastatic Pancreatic Neuroendocrine Tumors Predicts Novel Therapeutic Agents
A Scott, M Weitz, P Breheny, PH Ear, B Darbro, B Brown, T Braun, GY Li, ...
PANCREAS 49 (3), 485-485, 2020
2020
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