William Y. Kim, M.D.
William Y. Kim, M.D.
Professor of Medicine and Genetics, UNC
Verified email at med.unc.edu - Homepage
Cited by
Cited by
HIFα targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing
M Ivan, K Kondo, H Yang, W Kim, J Valiando, M Ohh, A Salic, JM Asara, ...
Science 292 (5516), 464-468, 2001
Role of VHL gene mutation in human cancer
WY Kim, WG Kaelin
Journal of Clinical Oncology 22 (24), 4991-5004, 2004
The Regulation of INK4/ARF in Cancer and Aging
WY Kim, NE Sharpless
Cell 127 (2), 265-275, 2006
Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer
JS Duncan, MC Whittle, K Nakamura, AN Abell, AA Midland, ...
Cell 149 (2), 307-321, 2012
Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology
JS Damrauer, KA Hoadley, DD Chism, C Fan, CJ Tiganelli, SE Wobker, ...
Proceedings of the National Academy of Sciences 111 (8), 3110-3115, 2014
Inhibition of HIF2α is sufficient to suppress pVHL-defective tumor growth
K Kondo, WY Kim, M Lechpammer, WG Kaelin Jr, C Kemp
PLoS biology 1 (3), e83, 2003
The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies
H Ji, D Li, L Chen, T Shimamura, S Kobayashi, K McNamara, U Mahmood, ...
Cancer cell 9 (6), 485-495, 2006
Impact of molecular subtypes in muscle-invasive bladder cancer on predicting response and survival after neoadjuvant chemotherapy
R Seiler, HAD Ashab, N Erho, BWG van Rhijn, B Winters, J Douglas, ...
European urology 72 (4), 544-554, 2017
The cancer genome atlas comprehensive molecular characterization of renal cell carcinoma
CJ Ricketts, AA De Cubas, H Fan, CC Smith, M Lang, E Reznik, R Bowlby, ...
Cell reports 23 (1), 313-326. e5, 2018
Interleukin-6: a candidate mediator of human prostate cancer morbidity
DA Twillie, MA Eisenberger, MA Carducci, WS Hseih, WY Kim, ...
Urology 45 (3), 542-549, 1995
Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin production
M Safran, WY Kim, F O'Connell, L Flippin, V Günzler, JW Horner, ...
Proceedings of the National Academy of Sciences 103 (1), 105-110, 2006
VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail
AJ Evans, RC Russell, O Roche, TN Burry, JE Fish, VWK Chow, WY Kim, ...
Molecular and cellular biology 27 (1), 157-169, 2007
A consensus molecular classification of muscle-invasive bladder cancer
A Kamoun, A de Reyniès, Y Allory, G Sjödahl, AG Robertson, R Seiler, ...
European urology 77 (4), 420-433, 2020
Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors
J Carretero, T Shimamura, K Rikova, AL Jackson, MD Wilkerson, ...
Cancer cell 17 (6), 547-559, 2010
Failure to prolyl hydroxylate hypoxia‐inducible factor α phenocopies VHL inactivation in vivo
WY Kim, M Safran, MRM Buckley, BL Ebert, J Glickman, M Bosenberg, ...
The EMBO journal 25 (19), 4650-4662, 2006
The von Hippel–Lindau tumor suppressor protein: new insights into oxygen sensing and cancer
W Kim, WG Kaelin Jr
Current opinion in genetics & development 13 (1), 55-60, 2003
Neoadjuvant clinical trial with sorafenib for patients with stage II or higher renal cell carcinoma
CL Cowey, C Amin, RS Pruthi, EM Wallen, ME Nielsen, G Grigson, ...
Journal of Clinical Oncology 28 (9), 1502, 2010
Coexistent ARID1A–PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling
RL Chandler, JS Damrauer, JR Raab, JC Schisler, MD Wilkerson, ...
Nature communications 6 (1), 1-14, 2015
Regulation of endocytosis via the oxygen-sensing pathway
Y Wang, O Roche, MS Yan, G Finak, AJ Evans, JL Metcalf, BE Hast, ...
Nature medicine 15 (3), 319-324, 2009
An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells
M Ohh, WY Kim, JJ Moslehi, Y Chen, V Chau, MA Read, WG Kaelin
EMBO reports 3 (2), 177-182, 2002
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