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William Y. Kim, M.D.
William Y. Kim, M.D.
Professor of Medicine, Genetics, and Pharmacology UNC
Verified email at med.unc.edu - Homepage
Title
Cited by
Cited by
Year
HIFα targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing
M Ivan, K Kondo, H Yang, W Kim, J Valiando, M Ohh, A Salic, JM Asara, ...
Science 292 (5516), 464-468, 2001
54272001
Comprehensive molecular characterization of urothelial bladder carcinoma
Cancer Genome Atlas Research Network
Nature 507 (7492), 315, 2014
23262014
Role of VHL Gene Mutation in Human Cancer
WY Kim, WG Kaelin
Journal of clinical oncology 22 (24), 4991-5004, 2004
11432004
The Regulation of INK4/ARF in Cancer and Aging
WY Kim, NE Sharpless
Cell 127 (2), 265-275, 2006
11392006
Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology
JS Damrauer, KA Hoadley, DD Chism, C Fan, CJ Tiganelli, SE Wobker, ...
Proceedings of the national academy of sciences 111 (8), 3110-3115, 2014
7732014
Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer
JS Duncan, MC Whittle, K Nakamura, AN Abell, AA Midland, ...
Cell 149 (2), 307-321, 2012
7562012
Inhibition of HIF2α is sufficient to suppress pVHL-defective tumor growth
K Kondo, WY Kim, M Lechpammer, WG Kaelin Jr
PLoS biology 1 (3), e83, 2003
6742003
Impact of molecular subtypes in muscle-invasive bladder cancer on predicting response and survival after neoadjuvant chemotherapy
R Seiler, HAD Ashab, N Erho, BWG van Rhijn, B Winters, J Douglas, ...
European urology 72 (4), 544-554, 2017
6312017
The cancer genome atlas comprehensive molecular characterization of renal cell carcinoma
CJ Ricketts, AA De Cubas, H Fan, CC Smith, M Lang, E Reznik, R Bowlby, ...
Cell reports 23 (1), 313-326. e5, 2018
6212018
A consensus molecular classification of muscle-invasive bladder cancer
A Kamoun, A de Reyniès, Y Allory, G Sjödahl, AG Robertson, R Seiler, ...
European urology 77 (4), 420-433, 2020
6042020
The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies
H Ji, D Li, L Chen, T Shimamura, S Kobayashi, K McNamara, U Mahmood, ...
Cancer cell 9 (6), 485-495, 2006
5142006
Interleukin-6: a candidate mediator of human prostate cancer morbidity
DA Twillie, MA Eisenberger, MA Carducci, WS Hseih, WY Kim, ...
Urology 45 (3), 542-549, 1995
3571995
Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin production
M Safran, WY Kim, F O'Connell, L Flippin, V Günzler, JW Horner, ...
Proceedings of the National Academy of Sciences 103 (1), 105-110, 2006
3432006
VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail
AJ Evans, RC Russell, O Roche, TN Burry, JE Fish, VWK Chow, WY Kim, ...
Molecular and cellular biology 27 (1), 157-169, 2007
3232007
Failure to prolyl hydroxylate hypoxia‐inducible factor α phenocopies VHL inactivation in vivo
WY Kim, M Safran, MRM Buckley, BL Ebert, J Glickman, M Bosenberg, ...
The EMBO journal 25 (19), 4650-4662, 2006
2542006
Coexistent ARID1A–PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling
RL Chandler, JS Damrauer, JR Raab, JC Schisler, MD Wilkerson, ...
Nature communications 6 (1), 1-14, 2015
2502015
Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors
J Carretero, T Shimamura, K Rikova, AL Jackson, MD Wilkerson, ...
Cancer cell 17 (6), 547-559, 2010
2402010
The von Hippel–Lindau tumor suppressor protein: new insights into oxygen sensing and cancer
W Kim, WG Kaelin Jr
Current opinion in genetics & development 13 (1), 55-60, 2003
2292003
Neoadjuvant clinical trial with sorafenib for patients with stage II or higher renal cell carcinoma
CL Cowey, C Amin, RS Pruthi, EM Wallen, ME Nielsen, G Grigson, ...
Journal of Clinical Oncology 28 (9), 1502, 2010
2222010
An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells
M Ohh, WY Kim, JJ Moslehi, Y Chen, V Chau, MA Read, WG Kaelin
EMBO reports 3 (2), 177-182, 2002
2082002
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