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Keith L. Ligon
Keith L. Ligon
Associate Professor, Harvard Medical School
Verified email at dfci.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Integrative analysis of 111 reference human epigenomes
Roadmap Epigenomics Consortium Integrative analysis coordination Kundaje ...
Nature 518 (7539), 317-330, 2015
5157*2015
Malignant astrocytic glioma: genetics, biology, and paths to treatment
FB Furnari, T Fenton, RM Bachoo, A Mukasa, JM Stommel, A Stegh, ...
Genes & development 21 (21), 2683-2710, 2007
27212007
An integrative model of cellular states, plasticity, and genetics for glioblastoma
C Neftel, J Laffy, MG Filbin, T Hara, ME Shore, GJ Rahme, AR Richman, ...
Cell 178 (4), 835-849. e21, 2019
10892019
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies
JM Stommel, AC Kimmelman, H Ying, R Nabioullin, AH Ponugoti, ...
Science 318 (5848), 287-290, 2007
10612007
p16INK4a induces an age-dependent decline in islet regenerative potential
J Krishnamurthy, MR Ramsey, KL Ligon, C Torrice, A Koh, S Bonner-Weir, ...
Nature 443 (7110), 453-457, 2006
10452006
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
DB Keskin, AJ Anandappa, J Sun, I Tirosh, ND Mathewson, S Li, ...
Nature 565 (7738), 234-239, 2019
8642019
Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic TargetsGenomics of Brain Metastases
PK Brastianos, SL Carter, S Santagata, DP Cahill, A Taylor-Weiner, ...
Cancer discovery 5 (11), 1164-1177, 2015
8512015
Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis
RM Bachoo, EA Maher, KL Ligon, NE Sharpless, SS Chan, MJ You, ...
Cancer cell 1 (3), 269-277, 2002
8062002
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation
H Zheng, H Ying, H Yan, AC Kimmelman, DJ Hiller, AJ Chen, SR Perry, ...
Nature 455 (7216), 1129-1133, 2008
8052008
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
P Koivunen, S Lee, CG Duncan, G Lopez, G Lu, S Ramkissoon, ...
Nature 483 (7390), 484-488, 2012
7582012
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome
YJ Cho, A Tsherniak, P Tamayo, S Santagata, A Ligon, H Greulich, ...
Journal of clinical oncology 29 (11), 1424, 2011
7552011
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ...
Nature genetics 45 (8), 927-932, 2013
7252013
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma
U Schüller, VM Heine, J Mao, AT Kho, AK Dillon, YG Han, E Huillard, ...
Cancer cell 14 (2), 123-134, 2008
6622008
Emerging insights into the molecular and cellular basis of glioblastoma
GP Dunn, ML Rinne, J Wykosky, G Genovese, SN Quayle, IF Dunn, ...
Genes & development 26 (8), 756-784, 2012
6122012
Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations
PK Brastianos, PM Horowitz, S Santagata, RT Jones, A McKenna, G Getz, ...
Nature genetics 45 (3), 285-289, 2013
5972013
Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma
KL Ligon, E Huillard, S Mehta, S Kesari, H Liu, JA Alberta, RM Bachoo, ...
Neuron 53 (4), 503-517, 2007
5512007
Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination
B Emery, D Agalliu, JD Cahoy, TA Watkins, JC Dugas, SB Mulinyawe, ...
Cell 138 (1), 172-185, 2009
4952009
Smooth muscle myosin heavy chain exclusively marks the smooth muscle lineage during mouse embryogenesis.
JM Miano, P Cserjesi, KL Ligon, M Periasamy, EN Olson
Circulation research 75 (5), 803-812, 1994
4621994
Delivery of functional anti-miR-9 by mesenchymal stem cell–derived exosomes to glioblastoma multiforme cells conferred chemosensitivity
JL Munoz, SA Bliss, SJ Greco, SH Ramkissoon, KL Ligon, P Rameshwar
Molecular Therapy-Nucleic Acids 2, e126, 2013
4522013
Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis
P Cserjesi, D Brown, KL Ligon, GE Lyons, NG Copeland, DJ Gilbert, ...
Development 121 (4), 1099-1110, 1995
4501995
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