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Isabel Wilkinson
Isabel Wilkinson
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Title
Cited by
Cited by
Year
Chemical proteomics and phenotypic profiling identifies the aryl hydrocarbon receptor as a molecular target of the utrophin modulator ezutromid
IVL Wilkinson, KJ Perkins, H Dugdale, L Moir, A Vuorinen, ...
Angewandte Chemie International Edition 59 (6), 2420-2428, 2020
392020
Combining experimental strategies for successful target deconvolution
IVL Wilkinson, GC Terstappen, AJ Russell
Drug Discovery Today 25 (11), 1998-2005, 2020
322020
From diagnosis to therapy in Duchenne muscular dystrophy
A Babbs, M Chatzopoulou, B Edwards, SE Squire, IVL Wilkinson, ...
Biochemical Society Transactions 48 (3), 813-821, 2020
272020
Functionalised Cofactor Mimics for Interactome Discovery and Beyond
IVL Wilkinson, M Pfanzelt, SA Sieber
Angewandte Chemie International Edition 61 (29), e202201136, 2022
162022
Discovery and mechanism of action studies of 4, 6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy
A Vuorinen, IVL Wilkinson, M Chatzopoulou, B Edwards, SE Squire, ...
European Journal of Medicinal Chemistry 220, 113431, 2021
132021
Isolation, Structural Identification, Synthesis, and Pharmacological Profiling of 1,2-trans-Dihydro-1,2-diol Metabolites of the Utrophin Modulator Ezutromid
M Chatzopoulou, TDW Claridge, KE Davies, SG Davies, DJ Elsey, E Emer, ...
Journal of Medicinal Chemistry 63 (5), 2547-2556, 2019
112019
Characterisation of utrophin modulator SMT C1100 as a non-competitive inhibitor of firefly luciferase
IVL Wilkinson, JK Reynolds, SRG Galan, A Vuorinen, AJ Sills, E Pires, ...
Bioorganic Chemistry 94, 103395, 2020
82020
Profiling the Heme‐Binding Proteomes of Bacteria Using Chemical Proteomics
IVL Wilkinson, M Bottlinger, Y El Harraoui, SA Sieber
Angewandte Chemie International Edition 62 (9), e202212111, 2023
72023
The cyanobacterial “nutraceutical” phycocyanobilin inhibits cysteine protease legumain
IVL Wilkinson, G Castro‐Falcón, MC Roda‐Serrat, TN Purdy, J Straetener, ...
ChemBioChem 24 (5), e202200455, 2023
32023
Aminothiazolones as potent, selective and cell active inhibitors of the PIM kinase family
CE Quevedo, CJR Bataille, S Byrne, M Durbin, J Elkins, A Guillermo, ...
Bioorganic & Medicinal Chemistry 28 (22), 115724, 2020
32020
A tubulin binding molecule drives differentiation of acute myeloid leukemia cells
TR Jackson, A Vuorinen, L Josa-Culleré, KS Madden, D Conole, ...
Iscience 25 (8), 2022
22022
A novel tubulin binding molecule drives differentiation of acute myeloid leukaemia cells
TR Jackson, A Vuorinen, L Josa-Culleré, KS Madden, D Conole, ...
bioRxiv, 2021.06. 03.446952, 2021
22021
International Commission on the Clinical Use of Human Germline Genome Editing
K DAVIES, RP LIFTON, H AKUTSU, R CALIFF, D CARROLL, ...
The National Academies os Sciences, Engineering Medicine, 2021
12021
Soil structure and its benefits - an evidence synthesis. The Royal Society.
https://royalsociety.org/-/media/policy/projects/soil-structures/soil …, 2020
2020
Target identification studies of a utrophin modulator for treatment of Duchenne muscular dystrophy
I Wilkinson, A Vuorinen, J Reynolds, K Perkins, H Dugdale, S Squire, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019
2019
Mechanism of action studies of the utrophin modulator ezutromid for the treatment of Duchenne muscular dystrophy
I Wilkinson
University of Oxford, 2019
2019
Small molecule utrophin modulators for the therapy of Duchenne muscular dystrophy (DMD)
A Russell, A Vuorinen, N Willis, D Conole, M Chatzopoulou, E Emer, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018
2018
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