Reciprocal signaling between glioblastoma stem cells and differentiated tumor cells promotes malignant progression X Wang, BC Prager, Q Wu, LJY Kim, RC Gimple, Y Shi, K Yang, ... Cell stem cell 22 (4), 514-528. e5, 2018 | 219 | 2018 |
Targeting glioblastoma stem cells through disruption of the circadian clock Z Dong, G Zhang, M Qu, RC Gimple, Q Wu, Z Qiu, BC Prager, X Wang, ... Cancer discovery 9 (11), 1556-1573, 2019 | 188 | 2019 |
Glioma stem cell–specific superenhancer promotes polyunsaturated fatty-acid synthesis to support EGFR signaling RC Gimple, RL Kidwell, LJY Kim, T Sun, AD Gromovsky, Q Wu, M Wolf, ... Cancer discovery 9 (9), 1248-1267, 2019 | 140 | 2019 |
Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells X Wang, K Yang, Q Wu, LJY Kim, AR Morton, RC Gimple, BC Prager, ... Science translational medicine 11 (504), eaau4972, 2019 | 125 | 2019 |
Cellular origin of glioblastoma and its implication in precision therapy M Yao, S Li, X Wu, S Diao, G Zhang, H He, L Bian, Y Lu Cellular & molecular immunology 15 (8), 737-739, 2018 | 82 | 2018 |
p53 pathway is involved in cell competition during mouse embryogenesis G Zhang, Y Xie, Y Zhou, C Xiang, L Chen, C Zhang, X Hou, J Chen, ... Proceedings of the National Academy of Sciences 114 (3), 498-503, 2017 | 56 | 2017 |
p53 in the myeloid lineage modulates an inflammatory microenvironment limiting initiation and invasion of intestinal tumors XY He, C Xiang, CX Zhang, YY Xie, L Chen, GX Zhang, Y Lu, G Liu Cell reports 13 (5), 888-897, 2015 | 49 | 2015 |
Chromatin remodeler HELLS maintains glioma stem cells through E2F3 and MYC G Zhang, Z Dong, BC Prager, LJK Kim, Q Wu, RC Gimple, X Wang, S Bao, ... JCI insight 4 (7), 2019 | 37 | 2019 |
Circadian regulator BMAL1:: CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle M Qu, G Zhang, H Qu, A Vu, R Wu, H Tsukamoto, Z Jia, W Huang, ... Proceedings of the National Academy of Sciences 120 (2), e2214829120, 2023 | 35 | 2023 |
Transcription elongation machinery is a druggable dependency and potentiates immunotherapy in glioblastoma stem cells Z Qiu, L Zhao, JZ Shen, Z Liang, Q Wu, K Yang, L Min, RC Gimple, ... Cancer discovery 12 (2), 502-521, 2022 | 35 | 2022 |
PDGF signaling inhibits mitophagy in glioblastoma stem cells through N6-methyladenosine D Lv, RC Gimple, C Zhong, Q Wu, K Yang, BC Prager, B Godugu, Z Qiu, ... Developmental cell 57 (12), 1466-1481. e6, 2022 | 32 | 2022 |
ADAR1-mediated RNA editing links ganglioside catabolism to glioblastoma stem cell maintenance L Jiang, Y Hao, C Shao, Q Wu, BC Prager, RC Gimple, G Sulli, LJY Kim, ... The Journal of clinical investigation 132 (6), 2022 | 28 | 2022 |
A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells JZ Shen, Z Qiu, Q Wu, G Zhang, R Harris, D Sun, J Rantala, WD Barshop, ... Molecular cell 82 (6), 1123-1139. e8, 2022 | 19 | 2022 |
A p53-based genetic tracing system to follow postnatal cardiomyocyte expansion in heart regeneration Q Xiao, G Zhang, H Wang, L Chen, S Lu, D Pan, G Liu, Z Yang Development 144 (4), 580-589, 2017 | 17 | 2017 |
Glioblastoma stem cells reprogram chromatin in vivo to generate selective therapeutic dependencies on DPY30 and phosphodiesterases D Dixit, BC Prager, RC Gimple, TE Miller, Q Wu, S Yomtoubian, ... Science Translational Medicine 14 (626), eabf3917, 2022 | 14 | 2022 |
Increased glycolysis in skeletal muscle coordinates with adipose tissue in systemic metabolic homeostasis C Xiang, Y Zhang, Q Chen, A Sun, Y Peng, G Zhang, D Zhou, Y Xie, ... Journal of Cellular and Molecular Medicine 25 (16), 7840-7854, 2021 | 9 | 2021 |
BAC transgenic mice provide evidence that p53 expression is highly regulated in vivo L Chen, GX Zhang, Y Zhou, CX Zhang, YY Xie, C Xiang, XY He, Q Zhang, ... Cell Death & Disease 6 (9), e1878-e1878, 2015 | 9 | 2015 |
Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe G Zhang, Z Dong, RC Gimple, A Wolin, Q Wu, Z Qiu, LM Wood, JZ Shen, ... Journal of Experimental Medicine 218 (11), e20202669, 2021 | 8 | 2021 |
Mouse double minute 2 actively suppresses p53 activity in oocytes during mouse folliculogenesis CX Zhang, Q Zhang, YY Xie, XY He, C Xiang, XS Hou, Y Zhou, L Chen, ... The American Journal of Pathology 187 (2), 339-351, 2017 | 7 | 2017 |
Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting RC Gimple, G Zhang, S Wang, T Huang, J Lee, S Taori, D Lv, D Dixit, ... JCI insight 8 (6), 2023 | 5 | 2023 |