Melissa J. Moore
Melissa J. Moore
Moderna Therapeutics/UMass Medical School
Verified email at
Cited by
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The RNA world: the nature of modern RNA suggests a prebiotic RNA
F Gesteland Raymond, C Thomas, F Atkins John
Cold Spring Harbor Laboratory Press, 2006
Pre-mRNA splicing: awash in a sea of proteins
MS Jurica, MJ Moore
Molecular cell 12 (1), 5-14, 2003
From birth to death: the complex lives of eukaryotic mRNAs
MJ Moore
Science 309 (5740), 1514-1518, 2005
The spliceosome deposits multiple proteins 20–24 nucleotides upstream of mRNA exon–exon junctions
H Le Hir, E Izaurralde, LE Maquat, MJ Moore
The EMBO journal 19 (24), 6860-6869, 2000
Pre-mRNA processing reaches back totranscription and ahead to translation
MJ Moore, NJ Proudfoot
Cell 136 (4), 688-700, 2009
The exon–exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay
H Le Hir, D Gatfield, E Izaurralde, MJ Moore
The EMBO journal 20 (17), 4987-4997, 2001
A long noncoding RNA mediates both activation and repression of immune response genes
S Carpenter, D Aiello, MK Atianand, EP Ricci, P Gandhi, LL Hall, M Byron, ...
science 341 (6147), 789-792, 2013
Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals
U Sharma, CC Conine, JM Shea, A Boskovic, AG Derr, XY Bing, ...
Science 351 (6271), 391-396, 2016
How introns influence and enhance eukaryotic gene expression
H Le Hir, A Nott, MJ Moore
Trends in biochemical sciences 28 (4), 215-220, 2003
Site-specific modification of pre-mRNA: the 2′-hydroxyl groups at the splice sites
MJ Moore, PA Sharp
Science 256 (5059), 992-997, 1992
Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis
CH Wu, C Fallini, N Ticozzi, PJ Keagle, PC Sapp, K Piotrowska, P Lowe, ...
Nature 488 (7412), 499-503, 2012
The immediate early gene arc/arg3. 1: regulation, mechanisms, and function
CR Bramham, PF Worley, MJ Moore, JF Guzowski
Journal of Neuroscience 28 (46), 11760-11767, 2008
A quantitative analysis of intron effects on mammalian gene expression
A Nott, SH Meislin, MJ Moore
Rna 9 (5), 607-617, 2003
Splicing enhances translation in mammalian cells: an additional function of the exon junction complex
A Nott, H Le Hir, MJ Moore
Genes & development 18 (2), 210-222, 2004
Identification of Neuronal RNA Targets of TDP-43-containing Ribonucleoprotein Complexes*♦
CF Sephton, C Cenik, A Kucukural, EB Dammer, B Cenik, YH Han, ...
Journal of biological chemistry 286 (2), 1204-1215, 2011
Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon–exon junctions
H Le Hir, MJ Moore, LE Maquat
Genes & development 14 (9), 1098-1108, 2000
Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis
MS Jurica, LJ Licklider, SP Gygi, N Grigorieff, MJ Moore
Rna 8 (4), 426-439, 2002
Evidence for two active sites in the spliceosome provided by stereochemistry of pre-mRNA splicing
MJ Moore, PA Sharp
Nature 365 (6444), 364-368, 1993
A long noncoding RNA lincRNA-EPS acts as a transcriptional brake to restrain inflammation
MK Atianand, W Hu, AT Satpathy, Y Shen, EP Ricci, ...
Cell 165 (7), 1672-1685, 2016
eIF4AIII binds spliced mRNA in the exon junction complex and is essential for nonsense-mediated decay
T Shibuya, TŘ Tange, N Sonenberg, MJ Moore
Nature structural & molecular biology 11 (4), 346-351, 2004
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