| MicroRNA pharmacoepigenetics: posttranscriptional regulation mechanisms behind variable drug disposition and strategy to develop more effective therapy AM Yu, Y Tian, MJ Tu, PY Ho, JL Jilek Drug Metabolism and Disposition 44 (3), 308-319, 2016 | 69 | 2016 |
| Bioengineered NRF2-siRNA is effective to interfere with NRF2 pathways and improve chemosensitivity of human cancer cells PC Li, MJ Tu, PY Ho, JL Jilek, Z Duan, QY Zhang, AX Yu, AM Yu Drug Metabolism and Disposition 46 (1), 2-10, 2018 | 63 | 2018 |
| Bioengineering novel chimeric microRNA-34a for prodrug cancer therapy: high-yield expression and purification, and structural and functional characterization WP Wang, PY Ho, QX Chen, B Addepalli, PA Limbach, MM Li, WJ Wu, ... Journal of Pharmacology and Experimental Therapeutics 354 (2), 131-141, 2015 | 62 | 2015 |
| Bioengineered noncoding RNAs selectively change cellular miRNome profiles for cancer therapy PY Ho, Z Duan, N Batra, JL Jilek, MJ Tu, JX Qiu, Z Hu, T Wun, PN Lara, ... Journal of Pharmacology and Experimental Therapeutics 365 (3), 494-506, 2018 | 54 | 2018 |
| A reliable LC-MS/MS method for the quantification of natural amino acids in mouse plasma: method validation and application to a study on amino acid dynamics during … Z Liu, MJ Tu, C Zhang, JL Jilek, QY Zhang, AM Yu Journal of Chromatography B 1124, 72-81, 2019 | 44 | 2019 |
| Lipidation of polyethylenimine-based polyplex increases serum stability of bioengineered RNAi agents and offers more consistent tumoral gene knockdown in vivo QY Zhang, PY Ho, MJ Tu, JL Jilek, QX Chen, S Zeng, AM Yu International journal of pharmaceutics 547 (1-2), 537-544, 2018 | 43 | 2018 |
| Bioengineered Let-7c inhibits orthotopic hepatocellular carcinoma and improves overall survival with minimal immunogenicity JL Jilek, QY Zhang, MJ Tu, PY Ho, Z Duan, JX Qiu, AM Yu Molecular Therapy-Nucleic Acids 14, 498-508, 2019 | 33 | 2019 |
| Mono-2-ethylhexyl phthalate disrupts neurulation and modifies the embryonic redox environment and gene expression KE Sant, DC Dolinoy, JL Jilek, MA Sartor, C Harris Reproductive Toxicology 63, 32-48, 2016 | 31 | 2016 |
| Effects of microRNA-34a on the pharmacokinetics of cytochrome P450 probe drugs in mice JL Jilek, Y Tian, AM Yu Drug Metabolism and Disposition 45 (5), 512-522, 2017 | 28 | 2017 |
| Nucleoside reverse transcriptase inhibitor interaction with human equilibrative nucleoside transporters 1 and 2 SR Miller, RK Hau, JL Jilek, MN Morales, SH Wright, NJ Cherrington Drug Metabolism and Disposition 48 (7), 603-612, 2020 | 20 | 2020 |
| Predicting drug interactions with human equilibrative nucleoside transporters 1 and 2 using functional knockout cell lines and Bayesian modeling SR Miller, X Zhang, RK Hau, JL Jilek, EQ Jennings, JJ Galligan, DH Foil, ... Molecular Pharmacology 99 (2), 147-162, 2021 | 18 | 2021 |
| Pharmacokinetic and pharmacodynamic factors contribute to synergism between Let-7c-5p and 5-fluorouracil in inhibiting hepatocellular carcinoma cell viability JL Jilek, MJ Tu, C Zhang, AM Yu Drug Metabolism and Disposition 48 (12), 1257-1263, 2020 | 18 | 2020 |
| Ethanol attenuates histiotrophic nutrition pathways and alters the intracellular redox environment and thiol proteome during rat organogenesis JL Jilek, KE Sant, KH Cho, MS Reed, J Pohl, JM Hansen, C Harris Toxicological Sciences 147 (2), 475-489, 2015 | 18 | 2015 |
| Mono-2-ethylhexyl phthalate (MEHP) alters histiotrophic nutrition pathways and epigenetic processes in the developing conceptus KE Sant, DC Dolinoy, JL Jilek, BJ Shay, C Harris The Journal of nutritional biochemistry 27, 211-218, 2016 | 16 | 2016 |
| Amino acid starvation induced by protease inhibition produces differential alterations in redox status and the thiol proteome in organogenesis-stage rat embryos and visceral … C Harris, JL Jilek, KE Sant, J Pohl, M Reed, JM Hansen The Journal of nutritional biochemistry 26 (12), 1589-1598, 2015 | 12 | 2015 |
| Altered cisplatin pharmacokinetics during nonalcoholic steatohepatitis contributes to reduced nephrotoxicity JL Jilek, KL Frost, KA Jacobus, W He, EL Toth, M Goedken, ... Acta Pharmaceutica Sinica B 11 (12), 3869-3878, 2021 | 8 | 2021 |
| Attenuated ochratoxin A transporter expression in a mouse model of nonalcoholic steatohepatitis protects against proximal convoluted tubule toxicity JL Jilek, KL Frost, S Marie, CM Myers, M Goedken, SH Wright, ... Drug Metabolism and Disposition 50 (10), 1389-1395, 2022 | 7 | 2022 |
| Increased renal expression of complement components in patients with liver diseases: nonalcoholic steatohepatitis, alcohol-associated, viral hepatitis, and alcohol-viral … KL Frost, JL Jilek, AD Thompson, RR Klein, S Sinari, ... Toxicological Sciences 189 (1), 62-72, 2022 | 6 | 2022 |
| Testicular disposition of clofarabine in rats is dependent on equilibrative nucleoside transporters SR Miller, JL Jilek, ME McGrath, RK Hau, EQ Jennings, JJ Galligan, ... Pharmacology Research & Perspectives 9 (4), e00831, 2021 | 6 | 2021 |
| Renal Transporter Alterations in Patients with Chronic Liver Diseases: Nonalcoholic Steatohepatitis, Alcohol-Associated, Viral Hepatitis, and Alcohol-Viral Combination KL Frost, JL Jilek, S Sinari, RR Klein, D Billheimer, SH Wright, ... Drug Metabolism and Disposition 51 (2), 155-164, 2023 | 4 | 2023 |
