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Chris Hlynialuk
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Caspase-2 cleavage of tau reversibly impairs memory
X Zhao, LA Kotilinek, B Smith, C Hlynialuk, K Zahs, M Ramsden, J Cleary, ...
Nature medicine 22 (11), 1268-1276, 2016
1922016
Factors other than hTau overexpression that contribute to tauopathy-like phenotype in rTg4510 mice
J Gamache, K Benzow, C Forster, L Kemper, C Hlynialuk, E Furrow, ...
Nature communications 10 (1), 2479, 2019
1512019
Mouse endogenous retroviruses can trigger premature transcriptional termination at a distance
J Li, K Akagi, Y Hu, AL Trivett, CJW Hlynialuk, DA Swing, N Volfovsky, ...
Genome research 22 (5), 870-884, 2012
592012
The mitochondrial metallochaperone SCO1 is required to sustain expression of the high-affinity copper transporter CTR1 and preserve copper homeostasis
CJ Hlynialuk, B Ling, ZN Baker, PA Cobine, DY Lisa, A Boulet, T Wai, ...
Cell reports 10 (6), 933-943, 2015
442015
Components of the Vid30c are needed for the rapamycin-induced degradation of the high-affinity hexose transporter Hxt7p in Saccharomyces cerevisiae
C Snowdon, C Hlynialuk, G Van Der Merwe
FEMS yeast research 8 (2), 204-216, 2008
292008
Nsf1/Ypl230w participates in transcriptional activation during non-fermentative growth and in response to salt stress in Saccharomyces cerevisiae
C Hlynialuk, R Schierholtz, A Vernooy, G van der Merwe
Microbiology 154 (8), 2482-2491, 2008
282008
Developmental pathogenicity of 4-repeat human tau is lost with the P301L mutation in genetically matched tau-transgenic mice
JE Gamache, L Kemper, E Steuer, K Leinonen-Wright, JM Choquette, ...
Journal of Neuroscience 40 (1), 220-236, 2020
132020
Caspase-2 inhibitor blocks tau truncation and restores excitatory neurotransmission in neurons modeling FTDP-17 tauopathy
G Singh, P Liu, KR Yao, JM Strasser, C Hlynialuk, K Leinonen-Wright, ...
ACS chemical neuroscience 13 (10), 1549-1557, 2022
62022
Blocking site-specific cleavage of human tau delays progression of disease-related phenotypes in genetically matched tau-transgenic mice modeling frontotemporal dementia
EL Steuer, LJ Kemper, CJW Hlynialuk, K Leinonen-Wright, ML Montonye, ...
Journal of Neuroscience 42 (23), 4737-4754, 2022
52022
Caspase-2 mRNA levels are not elevated in mild cognitive impairment, Alzheimer’s disease, Huntington’s disease, or Lewy Body dementia
C Hlynialuk, L Kemper, K Leinonen-Wright, RC Petersen, K Ashe, B Smith
PloS one 17 (9), e0274784, 2022
32022
Aβ* 56 is a stable oligomer that impairs memory function in mice
P Liu, IP Lapcinski, CJW Hlynialuk, EL Steuer, TJ Loude, SL Shapiro, ...
iScience, 2024
2024
Site-specific blockage of caspase-2-mediated endogenous tau processing ameliorates deficits in amyloid precursor protein transgenic mice modeling Alzheimer’s disease
P Liu, L Kemper, P Teravskis, C Hlynialuk, B Smith, J Gamache, ...
AAIC Neuroscience Next, 2020
2020
Saccharomyces cerevisiae
C Snowdon, C Hlynialuk, G van der Merwe
2007
An investigation of the role of VID28 in gluconeogenesis and stress response of the yeast Saccharomyces Cerevisiae
CJW Hlynialuk
University of Guelph, 2006
2006
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Articles 1–14