Caspase-2 cleavage of tau reversibly impairs memory X Zhao, LA Kotilinek, B Smith, C Hlynialuk, K Zahs, M Ramsden, J Cleary, ... Nature medicine 22 (11), 1268-1276, 2016 | 192 | 2016 |
Factors other than hTau overexpression that contribute to tauopathy-like phenotype in rTg4510 mice J Gamache, K Benzow, C Forster, L Kemper, C Hlynialuk, E Furrow, ... Nature communications 10 (1), 2479, 2019 | 151 | 2019 |
Mouse endogenous retroviruses can trigger premature transcriptional termination at a distance J Li, K Akagi, Y Hu, AL Trivett, CJW Hlynialuk, DA Swing, N Volfovsky, ... Genome research 22 (5), 870-884, 2012 | 59 | 2012 |
The mitochondrial metallochaperone SCO1 is required to sustain expression of the high-affinity copper transporter CTR1 and preserve copper homeostasis CJ Hlynialuk, B Ling, ZN Baker, PA Cobine, DY Lisa, A Boulet, T Wai, ... Cell reports 10 (6), 933-943, 2015 | 44 | 2015 |
Components of the Vid30c are needed for the rapamycin-induced degradation of the high-affinity hexose transporter Hxt7p in Saccharomyces cerevisiae C Snowdon, C Hlynialuk, G Van Der Merwe FEMS yeast research 8 (2), 204-216, 2008 | 29 | 2008 |
Nsf1/Ypl230w participates in transcriptional activation during non-fermentative growth and in response to salt stress in Saccharomyces cerevisiae C Hlynialuk, R Schierholtz, A Vernooy, G van der Merwe Microbiology 154 (8), 2482-2491, 2008 | 28 | 2008 |
Developmental pathogenicity of 4-repeat human tau is lost with the P301L mutation in genetically matched tau-transgenic mice JE Gamache, L Kemper, E Steuer, K Leinonen-Wright, JM Choquette, ... Journal of Neuroscience 40 (1), 220-236, 2020 | 13 | 2020 |
Caspase-2 inhibitor blocks tau truncation and restores excitatory neurotransmission in neurons modeling FTDP-17 tauopathy G Singh, P Liu, KR Yao, JM Strasser, C Hlynialuk, K Leinonen-Wright, ... ACS chemical neuroscience 13 (10), 1549-1557, 2022 | 6 | 2022 |
Blocking site-specific cleavage of human tau delays progression of disease-related phenotypes in genetically matched tau-transgenic mice modeling frontotemporal dementia EL Steuer, LJ Kemper, CJW Hlynialuk, K Leinonen-Wright, ML Montonye, ... Journal of Neuroscience 42 (23), 4737-4754, 2022 | 5 | 2022 |
Caspase-2 mRNA levels are not elevated in mild cognitive impairment, Alzheimer’s disease, Huntington’s disease, or Lewy Body dementia C Hlynialuk, L Kemper, K Leinonen-Wright, RC Petersen, K Ashe, B Smith PloS one 17 (9), e0274784, 2022 | 3 | 2022 |
Aβ* 56 is a stable oligomer that impairs memory function in mice P Liu, IP Lapcinski, CJW Hlynialuk, EL Steuer, TJ Loude, SL Shapiro, ... iScience, 2024 | | 2024 |
Site-specific blockage of caspase-2-mediated endogenous tau processing ameliorates deficits in amyloid precursor protein transgenic mice modeling Alzheimer’s disease P Liu, L Kemper, P Teravskis, C Hlynialuk, B Smith, J Gamache, ... AAIC Neuroscience Next, 2020 | | 2020 |
Saccharomyces cerevisiae C Snowdon, C Hlynialuk, G van der Merwe | | 2007 |
An investigation of the role of VID28 in gluconeogenesis and stress response of the yeast Saccharomyces Cerevisiae CJW Hlynialuk University of Guelph, 2006 | | 2006 |