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Liang Juin Tan
Liang Juin Tan
Verified email at imcb.a-star.edu.sg
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Structural and molecular myelination deficits occur prior to neuronal loss in the YAC128 and BACHD models of Huntington disease
RTY Teo, X Hong, L Yu-Taeger, Y Huang, LJ Tan, Y Xie, XV To, L Guo, ...
Human molecular genetics 25 (13), 2621-2632, 2016
992016
Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease
M Garcia-Miralles, X Hong, LJ Tan, NS Caron, Y Huang, XV To, RY Lin, ...
Scientific reports 6 (1), 31652, 2016
722016
ABCA8 regulates cholesterol efflux and high-density lipoprotein cholesterol levels
L Trigueros-Motos, JC van Capelleveen, F Torta, D Castano, LH Zhang, ...
Arteriosclerosis, thrombosis, and vascular biology 37 (11), 2147-2155, 2017
612017
Treatment with the MAO-A inhibitor clorgyline elevates monoamine neurotransmitter levels and improves affective phenotypes in a mouse model of Huntington disease
M Garcia-Miralles, J Ooi, CF Bardile, LJ Tan, M George, CL Drum, RY Lin, ...
Experimental neurology 278, 4-10, 2016
492016
Early pridopidine treatment improves behavioral and transcriptional deficits in YAC128 Huntington disease mice
M Garcia-Miralles, M Geva, JY Tan, NABM Yusof, Y Cha, R Kusko, LJ Tan, ...
JCI insight 2 (23), 2017
442017
Laquinimod treatment improves myelination deficits at the transcriptional and ultrastructural levels in the YAC128 mouse model of Huntington disease
M Garcia-Miralles, NABM Yusof, JY Tan, CI Radulescu, H Sidik, LJ Tan, ...
Molecular neurobiology 56, 4464-4478, 2019
362019
Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse
R Kusko, J Dreymann, J Ross, Y Cha, R Escalante-Chong, ...
Molecular Neurodegeneration 13, 1-15, 2018
362018
Impaired remyelination in a mouse model of Huntington disease
RTY Teo, C Ferrari Bardile, YL Tay, NABM Yusof, CA Kreidy, LJ Tan, ...
Molecular neurobiology 56, 6873-6882, 2019
202019
Connectomic imaging reveals Huntington‐related pathological and pharmaceutical effects in a mouse model
WT Chang, F Puspitasari, M Garcia‐Miralles, LY Yeow, HC Tay, KB Koh, ...
NMR in Biomedicine 31 (12), e4007, 2018
162018
Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease. Sci Rep 6: 31652
M Garcia-Miralles, X Hong, LJ Tan, NS Caron, Y Huang, XV To, RY Lin, ...
72016
Ermin deficiency leads to compromised myelin, inflammatory milieu, and susceptibility to demyelinating insult
A Ziaei, M Garcia‐Miralles, CI Radulescu, H Sidik, A Silvin, HG Bae, ...
Brain Pathology 32 (5), e13064, 2022
52022
L6 Evaluation of pridopidine in the transgenic yac128 mouse model of huntington’s disease
MG Miralles, LJ Tan, M Lim, M Geva, MR Hayden, MA Pouladi
Journal of Neurology, Neurosurgery & Psychiatry 87 (Suppl 1), A92-A92, 2016
42016
Ermin deficiency as an inside-out model of inflammatory dysmyelination
A Ziaei, M Garcia-Miralles, CI Radulescu, H Sidik, A Silvin, HG Bae, ...
BioRxiv, 2020.06. 16.154781, 2020
12020
Understanding early molecular mechanisms of abnormal myelination in neurological conditions by characterising Ermin deficiency
SL Oh, A Ziaei, LJ Tan, KH Utami, MA Pouladi, SR Langley
2024
Evaluation of pridopidine in the transgenic YAC128 mouse model of Huntington disease
M Garcia-Miralles, N Yosuf, JY Tan, R Kusko, LJ Tan, X Xu, A Orbach, ...
JOURNAL OF NEUROCHEMISTRY 142, 219-219, 2017
2017
L8 Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of huntington’s disease
MG Miralles, X Hong, NS Caron, LJ Tan, Y Huang, XV To, RY Lin, ...
Journal of Neurology, Neurosurgery & Psychiatry 87 (Suppl 1), A92-A93, 2016
2016
TBM and DTI reveal structural changes by memantine treatment in YAC128 mouse model of Huntington disease
X Hong, M Garcia-Miralles, LY Yeow, XV To, BCM Yeo, F Puspitasari, ...
Proc. Intl. Soc. Mag. Reson. Med 24, 4440, 2016
2016
Imaging effects of memantine treatment in a mouse model of Huntington disease using evoked and resting-state fMRI
WT Chang, F Puspitasari, LY Yeow, HC Tay, MG Miralles, KB Koh, LJ Tan, ...
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