| GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts RM Sterner, R Sakemura, MJ Cox, N Yang, RH Khadka, CL Forsman, ... Blood, The Journal of the American Society of Hematology 133 (7), 697-709, 2019 | 517 | 2019 |
| Targeting Cancer-Associated Fibroblasts in the Bone Marrow Prevents Resistance to CART-Cell Therapy in Multiple Myeloma R Sakemura, M Hefazi, EL Siegler, MJ Cox, DP Larson, MJ Hansen, ... Blood, 2022 | 65 | 2022 |
| Leukemic extracellular vesicles induce chimeric antigen receptor T cell dysfunction in chronic lymphocytic leukemia MJ Cox, F Lucien, R Sakemura, JC Boysen, Y Kim, P Horvei, CM Roman, ... Molecular Therapy 29 (4), 1529-1540, 2021 | 57 | 2021 |
| Using CRISPR/Cas9 to knock out GM-CSF in CAR-T cells RM Sterner, MJ Cox, R Sakemura, SS Kenderian JoVE (Journal of Visualized Experiments), e59629, 2019 | 43 | 2019 |
| Resistance to CART cell therapy: lessons learned from the treatment of hematological malignancies R Sakemura, MJ Cox, M Hefazi, EL Siegler, SS Kenderian Leukemia & Lymphoma 62 (9), 2052-2063, 2021 | 20 | 2021 |
| Development of a Clinically Relevant Reporter for Chimeric Antigen Receptor T-cell Expansion, Trafficking, and Toxicity R Sakemura, A Bansal, EL Siegler, M Hefazi, N Yang, RH Khadka, ... Cancer Immunology Research 9 (9), 1035-1046, 2021 | 19 | 2021 |
| Targeting Cancer Associated Fibroblasts in the Bone Marrow Prevents Resistance to Chimeric Antigen Receptor T Cell Therapy in Multiple Myeloma R Sakemura, MJ Cox, MJ Hansen, M Hefazi, C Manriquez Roman, ... Blood, The Journal of the American Society of Hematology 134 (Supplement_1 …, 2019 | 19 | 2019 |
| GM-CSF disruption in CART cells modulates T cell activation and enhances CART cell anti-tumor activity MJ Cox, C Manriquez Roman, EE Tapper, EL Siegler, D Chappell, ... Leukemia 36 (6), 1635-1645, 2022 | 14 | 2022 |
| Challenges of chimeric antigen receptor T-cell therapy in chronic lymphocytic leukemia: lessons learned. I Can, MJ Cox, EL Siegler, R Sakemura, SS Kenderian Experimental Hematology 108, 1-7, 2022 | 14 | 2022 |
| Targeting of CD19 By Tafasitamab Does Not Impair CD19 Directed Chimeric Antigen Receptor T Cell Activity in Vitro P Horvei, R Sakemura, MJ Cox, MW Ruff, M Hefazi, EE Tapper, KJ Schick, ... Blood, The Journal of the American Society of Hematology 134 (Supplement_1 …, 2019 | 11 | 2019 |
| Improved Anti-Tumor Response of Chimeric Antigen Receptor T Cell (CART) Therapy after GM-CSF Inhibition Is Mechanistically Supported By a Novel Direct Interaction of GM-CSF … MJ Cox, CJ Kuhlmann, RM Sterner, R Sakemura, S Sinha, R Mwangi, ... Blood, The Journal of the American Society of Hematology 134 (Supplement_1 …, 2019 | 10 | 2019 |
| Targeting of CD19 By Tafasitamab Does Not Impair CD19 Directed Chimeric Antigen Receptor T Cell Activity in Vitro P Horvei, R Sakemura, MJ Cox, CM Roman, KJ Schick, MW Ruff, ... Biology of Blood and Marrow Transplantation 26 (3), S223-S224, 2020 | 8 | 2020 |
| Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F] Tetrafluoroborate Positron Emission Tomography/Computed Tomography. R Sakemura, MJ Cox, A Bansal, CM Roman, M Hefazi, CJ Vernon, ... Journal of Visualized Experiments: Jove, 2022 | 6 | 2022 |
| Efficient Gene Editing of CART Cells with CRISPR-Cas12a for Enhanced Antitumor Efficacy EL Siegler, BW Simone, R Sakemura, EE Tapper, P Horvei, MJ Cox, ... Blood 136, 6-7, 2020 | 6 | 2020 |
| The Impact of Prior Treatment with a CD19 Targeting Monoclonal Antibody on Subsequent Treatment with CD19 Targeting CART Cell Therapy in Preclinical Models R Sakemura, P Horvei, C Manriquez-Roman, EJ Ogbodo, EE Tapper, ... Blood 138, 2412, 2021 | 4 | 2021 |
| Favorable Modulation of Chimeric Antigen Receptor T Cells Safety and Efficacy By the Non-Covalent BTK Inhibitor Vecabrutinib MM Adada, R Sakemura, MJ Cox, C Manriquez-Roman, EL Siegler, ... Blood 138, 906, 2021 | 4 | 2021 |
| Improved Anti-Tumor Response of Chimeric Antigen Receptor T Cell (CART) Therapy after GM-CSF Inhibition Is Mechanistically Supported By a Novel Direct Interaction of GM-CSF … MJ Cox, C Kuhlmann, RM Sterner, R Sakemura, S Sinha, M Hefazi, ... Biology of Blood and Marrow Transplantation 26 (3), S60-S61, 2020 | 4 | 2020 |
| GM-CSF Blockade during Chimeric Antigen Receptor T-Cell (CART) Therapy Reduces Cytokine Release Syndrome and Neurotoxicity and May Enhance CART Effector Functions RM Sterner, R Sakemura, N Yang, MJ Cox, R Khadka, CL Forsman, ... Biology of Blood and Marrow Transplantation 25 (3), S4, 2019 | 4 | 2019 |
| GM-CSF blockade during chimeric antigen receptor T cell therapy reduces cytokine release syndrome and neurotoxicity and may enhance their effector functions RM Sterner, R Sakemura, N Yang, MJ Cox, RH Khadka, CL Forsman, ... Blood, The Journal of the American Society of Hematology 132 (Supplement 1 …, 2018 | 4 | 2018 |
| Chimeric Antigen Receptor Engineering of Mesenchymal Stromal Cells (CAR-MSC) Enhance Immunosuppression and Outcomes in Graft Versus Host Disease (GvHD) Preclinical Models O Sirpilla, RL Sakemura, M Hefazi, JH Girsch, T Huynh, MJ Cox, ... Blood 140 (Supplement 1), 1579-1580, 2022 | 3 | 2022 |
Saad Sirop KenderianHematology and BMT, Mayo ClinicVerified email at mayo.edu
