| Complement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy SS Whitmore, EH Sohn, KR Chirco, AV Drack, EM Stone, BA Tucker, ... Progress in retinal and eye research 45, 1-29, 2015 | 228 | 2015 |
| Structural and molecular changes in the aging choroid: implications for age-related macular degeneration KR Chirco, EH Sohn, EM Stone, BA Tucker, RF Mullins Eye 31 (1), 10-25, 2017 | 172 | 2017 |
| CRISPR-Cas9 genome engineering: treating inherited retinal degeneration ER Burnight, JC Giacalone, JA Cooke, JR Thompson, LR Bohrer, ... Progress in retinal and eye research 65, 28-49, 2018 | 75 | 2018 |
| Selective accumulation of the complement membrane attack complex in aging choriocapillaris KR Chirco, BA Tucker, EM Stone, RF Mullins Experimental eye research 146, 393-397, 2016 | 65 | 2016 |
| Monomeric Creactive protein and inflammation in agerelated macular degeneration KR Chirco, SS Whitmore, K Wang, LA Potempa, JA Halder, EM Stone, ... The Journal of pathology 240 (2), 173-183, 2016 | 49 | 2016 |
| Toll-like receptor 2 facilitates oxidative damage-induced retinal degeneration K Mulfaul, E Ozaki, N Fernando, K Brennan, KR Chirco, E Connolly, ... Cell reports 30 (7), 2209-2224. e5, 2020 | 45 | 2020 |
| Connective tissue growth factor promotes efficient generation of human induced pluripotent stem cell-derived choroidal endothelium AE Songstad, KS Worthington, KR Chirco, JC Giacalone, SS Whitmore, ... Stem cells translational medicine 6 (6), 1533-1546, 2017 | 37 | 2017 |
| C-reactive protein as a mediator of complement activation and inflammatory signaling in age-related macular degeneration KR Chirco, LA Potempa Frontiers in immunology 9, 348408, 2018 | 33 | 2018 |
| Bulk and single-cell gene expression analyses reveal aging human choriocapillaris has pro-inflammatory phenotype AP Voigt, SS Whitmore, K Mulfaul, KR Chirco, JC Giacalone, ... Microvascular research 131, 104031, 2020 | 32 | 2020 |
| Preparation and evaluation of human choroid extracellular matrix scaffolds for the study of cell replacement strategies KR Chirco, KS Worthington, MJ Flamme-Wiese, MJ Riker, JD Andrade, ... Acta biomaterialia 57, 293-303, 2017 | 26 | 2017 |
| Allele-specific gene editing to rescue dominant CRX-associated LCA7 phenotypes in a retinal organoid model KR Chirco, S Chew, AT Moore, JL Duncan, DA Lamba Stem cell reports 16 (11), 2690-2702, 2021 | 25 | 2021 |
| Evaluation of serum and ocular levels of membrane attack complex and C-reactive protein in CFH-genotyped human donors KR Chirco, MJ Flamme-Wiese, JS Wiley, LA Potempa, EM Stone, ... Eye 32 (11), 1740-1742, 2018 | 15 | 2018 |
| Timed notch inhibition drives photoreceptor fate specification in human retinal organoids SH Chew, C Martinez, KR Chirco, S Kandoi, DA Lamba Investigative Ophthalmology & Visual Science 63 (10), 12-12, 2022 | 12 | 2022 |
| MANF delivery improves retinal homeostasis and cell replacement therapies in ageing mice J Neves, KR Chirco, W Cedron-Craft, S Chew, J Zhu, H Jasper, ... Experimental gerontology 134, 110893, 2020 | 12 | 2020 |
| Clinicopathological correlation in a patient with previously treated birdshot chorioretinopathy EH Sohn, KR Chirco, JC Folk, RF Mullins Retinal Cases and Brief Reports 11 (4), 344-347, 2017 | 12 | 2017 |
| Immunological considerations for retinal stem cell therapy J Kramer, KR Chirco, DA Lamba Pluripotent Stem Cells in Eye Disease Therapy, 99-119, 2019 | 11 | 2019 |
| Imidazole compounds for protecting choroidal endothelial cells from complement injury S Zeng, KK Wen, G Workalemahu, EH Sohn, M Wu, KR Chirco, ... Scientific reports 8 (1), 13387, 2018 | 7 | 2018 |
| MMP19 expression in the human optic nerve KR Chirco, RJ Hazlewood, K Miller, G Workalemahu, LM Jampol, ... Molecular vision 22, 1429, 2016 | 5 | 2016 |
| Advancements in pre-clinical development of gene editing-based therapies to treat inherited retinal diseases KR Chirco, C Martinez, DA Lamba Vision Research 209, 108257, 2023 | 4 | 2023 |
| TLR2 bridges oxidative damage and complement-associated pathology and is a therapeutic target for age-related macular degeneration. S Doyle, K Mulfaul, N Fernando, K Chirco, E Connolly, T Ryan, E Ozaki, ... Investigative Ophthalmology & Visual Science 59 (9), 3475-3475, 2018 | 2 | 2018 |
