Primary acute myeloid leukemia cells with overexpression of EVI-1 are sensitive to all-trans retinoic acid HJMP Verhagen, MA Smit, A Rutten, F Denkers, PJ Poddighe, PA Merle, ... Blood, The Journal of the American Society of Hematology 127 (4), 458-463, 2016 | 52 | 2016 |
Reprogramming acute myeloid leukemia into sensitivity for retinoic-acid-driven differentiation N van Gils, HJMP Verhagen, L Smit Experimental hematology 52, 12-23, 2017 | 47 | 2017 |
Rapid, sensitive, and specific severe acute respiratory syndrome coronavirus 2 detection: a multicenter comparison between standard quantitative reverse-transcriptase … E Brandsma, HJMP Verhagen, TJW van de Laar, ECJ Claas, ... The Journal of Infectious Diseases 223 (2), 206-213, 2021 | 37 | 2021 |
MKL1 deficiency results in a severe neutrophil motility defect due to impaired actin polymerization EGG Sprenkeler, SSV Henriet, ATJ Tool, IC Kreft, I van der Bijl, CEM Aarts, ... Blood, The Journal of the American Society of Hematology 135 (24), 2171-2181, 2020 | 35 | 2020 |
IGFBP7 induces apoptosis of acute myeloid leukemia cells and synergizes with chemotherapy in suppression of leukemia cell survival HJMP Verhagen, DC De Leeuw, MGM Roemer, F Denkers, W Pouwels, ... Cell death & disease 5 (6), e1300-e1300, 2014 | 35 | 2014 |
Rapid, sensitive and specific SARS coronavirus-2 detection: a multi-center comparison between standard qRT-PCR and CRISPR based DETECTR E Brandsma, HJMP Verhagen, TJW van de Laar, ECJ Claas, ... medRxiv, 2020.07. 27.20147249, 2020 | 22 | 2020 |
MicroRNA-551b is highly expressed in hematopoietic stem cells and a biomarker for relapse and poor prognosis in acute myeloid leukemia DC De Leeuw, H Verhagen, F Denkers, FG Kavelaars, PJM Valk, ... Leukemia 30 (3), 742-746, 2016 | 21 | 2016 |
IGFBP7 induces differentiation and loss of survival of human acute myeloid leukemia stem cells without affecting normal hematopoiesis HJMP Verhagen, N van Gils, T Martiañez, A van Rhenen, A Rutten, ... Cell reports 25 (11), 3021-3035. e5, 2018 | 19 | 2018 |
VEGFC antibody therapy drives differentiation of AML KR Kampen, FJG Scherpen, H Mahmud, A Ter Elst, AB Mulder, V Guryev, ... Cancer research 78 (20), 5940-5948, 2018 | 15 | 2018 |
IGFBP7 activates retinoid acid–induced responses in acute myeloid leukemia stem and progenitor cells N van Gils, HJMP Verhagen, A Rutten, RX Menezes, ML Tsui, E Vermue, ... Blood advances 4 (24), 6368-6383, 2020 | 6 | 2020 |
Targeting histone methylation to reprogram the transcriptional state that drives survival of drug-tolerant myeloid leukemia persisters N van Gils, HJMP Verhagen, M Broux, T Martiáñez, F Denkers, E Vermue, ... Iscience 25 (9), 2022 | 5 | 2022 |
Optimized Guide RNA Selection Improves Streptococcus pyogenes Cas9 Gene Editing of Human Hematopoietic Stem and Progenitor Cells HJMP Verhagen, C Kuijk, L Rutgers, AM Kokke, SA van der Meulen, ... The CRISPR Journal 5 (5), 702-716, 2022 | 4 | 2022 |