Tianyuan Lu
Tianyuan Lu
University of Toronto
Verified email at - Homepage
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Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases
Y Chen, T Lu, U Pettersson-Kymmer, ID Stewart, G Butler-Laporte, ...
Nature Genetics 55 (1), 44-53, 2023
H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation
AS Harutyunyan*, H Chen*, T Lu, C Horth, H Nikbakht, B Krug, C Russo, ...
Cell Reports 33 (7), 108390, 2020
Individuals with common diseases but with a low polygenic risk score could be prioritized for rare variant screening
T Lu, S Zhou, H Wu, V Forgetta, CMT Greenwood, JB Richards
Genetics in Medicine 23 (3), 508-515, 2021
Reshuffling of the ancestral core-eudicot genome shaped chromatin topology and epigenetic modification in Panax
ZH Wang, XF Wang, T Lu, MR Li, P Jiang, J Zhao, ST Liu, XQ Fu, ...
Nature Communications 13 (1), 1902, 2022
Improved prediction of fracture risk leveraging a genome-wide polygenic risk score
T Lu*, V Forgetta*, J Keller-Baruch, M Nethander, D Bennett, M Forest, ...
Genome Medicine 13 (1), 1-15, 2021
Polygenic risk for coronary heart disease acts through atherosclerosis in type 2 diabetes
T Lu, V Forgetta, OHY Yu, L Mokry, M Gregory, G Thanassoulis, ...
Cardiovascular Diabetology 19, 1-10, 2020
Proteome-wide Mendelian randomization implicates nephronectin as an actionable mediator of the effect of obesity on COVID-19 severity
S Yoshiji, G Butler-Laporte, T Lu, JDS Willett, CY Su, T Nakanishi, ...
Nature Metabolism 5 (2), 248-264, 2023
Investigating transcriptome-wide sex dimorphism by multi-level analysis of single-cell RNA sequencing data in ten mouse cell types
T Lu, JC Mar
Biology of sex Differences 11, 1-20, 2020
A Polygenic Risk Score to Predict Future Adult Short Stature Among Children
T Lu, V Forgetta, H Wu, JRB Perry, KK Ong, CMT Greenwood, ...
The Journal of Clinical Endocrinology & Metabolism 106 (7), 1918-1928, 2021
eXclusionarY: 10 years later, where are the sex chromosomes in GWASs?
L Sun, Z Wang, T Lu, TA Manolio, AD Paterson
The American Journal of Human Genetics 110 (6), 903-912, 2023
Transcriptional reprogramming of skeletal muscle stem cells by the niche environment
F Lazure*, R Farouni*, K Sahinyan, DM Blackburn, ...
Nature Communications 14 (1), 535, 2023
Circulating Proteins Influencing Psychiatric Disease: A Mendelian Randomization Study
T Lu, V Forgetta, CMT Greenwood, S Zhou, JB Richards
Biological Psychiatry 93 (1), 82-91, 2023
Polygenic risk score as a possible tool for identifying familial monogenic causes of complex diseases
T Lu, V Forgetta, JB Richards, CMT Greenwood
Genetics in Medicine 24 (7), 1545-1555, 2022
Pan-cancer analysis of mRNA stability for decoding tumour post-transcriptional programs
G Perron, P Jandaghi, E Moslemi, T Nishimura, M Rajaee, R Alkallas, ...
Communications Biology 5, 851, 2022
Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesis
T Lu, KO Klein, I Colmegna, M Lora, CMT Greenwood, M Hudson
BMC medical genomics 12, 1-12, 2019
Rapid Divergence Followed by Adaptation to Contrasting Ecological Niches of Two Closely Related Columbine Species Aquilegia japonica and A. oxysepala
MR Li, HY Wang, N Ding, T Lu, YC Huang, HX Xiao, B Liu, LF Li
Genome biology and evolution 11 (3), 919-930, 2019
Simultaneous SNP selection and adjustment for population structure in high dimensional prediction models
SR Bhatnagar, Y Yang, T Lu, E Schurr, JC Loredo-Osti, M Forest, ...
PLoS genetics 16 (5), e1008766, 2020
A Sparse Additive Model for High-Dimensional Interactions with an Exposure Variable
SR Bhatnagar, T Lu, A Lovato, DL Olds, MS Kobor, MJ Meaney, ...
Computational Statistics & Data Analysis, 107624, 2022
Capturing additional genetic risk from family history for improved polygenic risk prediction
T Lu, V Forgetta, JB Richards, CMT Greenwood
Communications Biology 5 (1), 595, 2022
Causal associations between body fat accumulation and COVID-19 severity: A Mendelian randomization study
S Yoshiji, D Tanaka, M Hiroto, T Lu, G Butler-Laporte, T Murakami, ...
Frontiers in Endocrinology 13, 899625, 2022
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