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Morgan Alexandra Coburn
Morgan Alexandra Coburn
University of Virginia, Eyo Lab
Verified email at uci.edu
Title
Cited by
Cited by
Year
Development and validation of a simplified method to generate human microglia from pluripotent stem cells
A McQuade, M Coburn, CH Tu, J Hasselmann, H Davtyan, ...
Molecular neurodegeneration 13, 1-13, 2018
2902018
Development of a chimeric model to study and manipulate human microglia in vivo
J Hasselmann, MA Coburn, W England, DXF Velez, SK Shabestari, ...
Neuron 103 (6), 1016-1033. e10, 2019
2552019
Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease
A McQuade, YJ Kang, J Hasselmann, A Jairaman, A Sotelo, M Coburn, ...
Nature communications 11 (1), 5370, 2020
2062020
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice
SK Shabestari, S Morabito, EP Danhash, A McQuade, JR Sanchez, ...
Cell reports 39 (11), 2022
642022
Behavioral impact of maternal allergic-asthma in two genetically distinct mouse strains
JJ Schwartzer, M Careaga, MA Coburn, DR Rose, HK Hughes, ...
Brain, behavior, and immunity 63, 99-107, 2017
542017
Perinatal exposure to concentrated ambient particulates results in autism-like behavioral deficits in adult mice
JS Church, PB Tijerina, FJ Emerson, MA Coburn, JL Blum, JT Zelikoff, ...
Neurotoxicology 65, 231-240, 2018
532018
Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice
H Davtyan, A Hovakimyan, S Kiani Shabestari, T Antonyan, MA Coburn, ...
Alzheimer's Research & Therapy 11, 1-13, 2019
232019
The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model
C Claes, WE England, EP Danhash, S Kiani Shabestari, A Jairaman, ...
Alzheimer's & Dementia 18 (10), 1765-1778, 2022
222022
A MultiTEP platform-based epitope vaccine targeting the phosphatase activating domain (PAD) of tau: Therapeutic efficacy in PS19 mice
A Hovakimyan, T Antonyan, SK Shabestari, O Svystun, G Chailyan, ...
Scientific reports 9 (1), 15455, 2019
192019
Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease. Nat. Commun. 11, 5370
A McQuade, YJ Kang, J Hasselmann, A Jairaman, A Sotelo, M Coburn, ...
132020
The emergence of the calvarial hematopoietic niche in health and disease
WA Mills III, MA Coburn, UB Eyo
Immunological reviews 311 (1), 26-38, 2022
82022
Distinguishing the effects of systemic CSF1R inhibition by PLX3397 on microglia and peripheral immune cells
AK Okojie, JO Uweru, MA Coburn, S Li, VD Cao-Dao, UB Eyo
Journal of Neuroinflammation 20 (1), 242, 2023
72023
Author Correction: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease
A McQuade, YJ Kang, J Hasselmann, A Jairaman, A Sotelo, M Coburn, ...
nature communications 14, 2023
42023
Microglia promote anti-tumour immunity and suppress breast cancer brain metastasis
KT Evans, K Blake, A Longworth, MA Coburn, J Insua-Rodríguez, ...
Nature Cell Biology 25 (12), 1848-1859, 2023
32023
Using Chimeric Models to Study the Interactions between Human Microglia and Alzheimer’s Disease Pathology in vivo
MA Coburn
University of California, Irvine, 2021
2021
Examining the effects of the microglial PLCG2 P522R mutation by transplantation of human stem cell‐derived microglia in chimeric AD mice: Molecular and cell biology/stem cells …
C Claes, E Danhash, J Hasselmann, JP Chadarevian, SK Shabestari, ...
Alzheimer's & Dementia 16, e041539, 2020
2020
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