| The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity PV Lishko, E Procko, X Jin, CB Phelps, R Gaudet Neuron 54 (6), 905-918, 2007 | 545 | 2007 |
| Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2 KK Chan, D Dorosky, P Sharma, SA Abbasi, JM Dye, DM Kranz, ... Science 369 (6508), 1261-1265, 2020 | 543 | 2020 |
| Chromatin remodeling, measured by a novel real-time polymerase chain reaction assay, across the proximal promoter region of the IL-2 gene S Rao, E Procko, MF Shannon The Journal of Immunology 167 (8), 4494-4503, 2001 | 234 | 2001 |
| The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter E Procko, ML O'Mara, WFD Bennett, DP Tieleman, R Gaudet The FASEB Journal 23 (5), 1287-1302, 2009 | 197 | 2009 |
| Distinct structural and functional properties of the ATPase sites in an asymmetric ABC transporter E Procko, I Ferrin-O'Connell, SL Ng, R Gaudet Molecular cell 24 (1), 51-62, 2006 | 170 | 2006 |
| A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells E Procko, GY Berguig, BW Shen, Y Song, S Frayo, AJ Convertine, ... Cell 157 (7), 1644-1656, 2014 | 141 | 2014 |
| An engineered decoy receptor for SARS-CoV-2 broadly binds protein S sequence variants KK Chan, TJC Tan, KK Narayanan, E Procko Science Advances 7 (8), eabf1738, 2021 | 130 | 2021 |
| Distinct properties of Ca2+–calmodulin binding to N- and C-terminal regulatory regions of the TRPV1 channel SY Lau, E Procko, R Gaudet Journal of General Physiology 140 (5), 541-555, 2012 | 119 | 2012 |
| Computational design of a protein-based enzyme inhibitor E Procko, R Hedman, K Hamilton, J Seetharaman, SJ Fleishman, M Su, ... Journal of molecular biology 425 (18), 3563-3575, 2013 | 114 | 2013 |
| Structural and energetic basis of folded-protein transport by the FimD usher S Geibel, E Procko, SJ Hultgren, D Baker, G Waksman Nature 496 (7444), 243-246, 2013 | 107 | 2013 |
| Structural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel H Inada, E Procko, M Sotomayor, R Gaudet Biochemistry 51 (31), 6195-6206, 2012 | 100 | 2012 |
| The sequence of human ACE2 is suboptimal for binding the S spike protein of SARS coronavirus 2 E Procko BioRxiv, 2020 | 90 | 2020 |
| Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer S Berger, E Procko, D Margineantu, EF Lee, BW Shen, A Zelter, DA Silva, ... elife 5, e20352, 2016 | 90 | 2016 |
| Identification of domain boundaries within the Ntermini of TAP1 and TAP2 and their importance in tapasin binding and tapasinmediated increase in peptide loading of MHC class I E Procko, G Raghuraman, DC Wiley, M Raghavan, R Gaudet Immunology and cell biology 83 (5), 475-482, 2005 | 74 | 2005 |
| Mapping interaction sites on human chemokine receptors by deep mutational scanning JD Heredia, J Park, RJ Brubaker, SK Szymanski, KS Gill, E Procko The Journal of Immunology 200 (11), 3825-3839, 2018 | 63 | 2018 |
| Antigen processing and presentation: TAPping into ABC transporters E Procko, R Gaudet Current opinion in immunology 21 (1), 84-91, 2009 | 63 | 2009 |
| Leukocytes on the move with phosphoinositide 3kinase and its downstream effectors E Procko, SR McColl Bioessays 27 (2), 153-163, 2005 | 63 | 2005 |
| Engineered ACE2 decoy mitigates lung injury and death induced by SARS-CoV-2 variants L Zhang, S Dutta, S Xiong, M Chan, KK Chan, TM Fan, KL Bailey, ... Nature Chemical Biology 18 (3), 342-351, 2022 | 62 | 2022 |
| Structural architecture of a dimeric class C GPCR based on co-trafficking of sweet taste receptor subunits J Park, B Selvam, K Sanematsu, N Shigemura, D Shukla, E Procko Journal of Biological Chemistry 294 (13), 4759-4774, 2019 | 53 | 2019 |
| Identifying mutation hotspots reveals pathogenetic mechanisms of KCNQ2 epileptic encephalopathy J Zhang, EC Kim, C Chen, E Procko, S Pant, K Lam, J Patel, R Choi, ... Scientific reports 10 (1), 4756, 2020 | 51 | 2020 |
