| Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors EJ Morris, S Jha, CR Restaino, P Dayananth, H Zhu, A Cooper, D Carr, ... Cancer discovery 3 (7), 742-750, 2013 | 706 | 2013 |
| Retinoblastoma protein partners EJ Morris, NJ Dyson Academic Press 82, 1-54, 2001 | 472 | 2001 |
| Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity. EJ Morris, HM Geller The Journal of cell biology 134 (3), 757-770, 1996 | 377 | 1996 |
| E2F1 represses β-catenin transcription and is antagonized by both pRB and CDK8 EJ Morris, JY Ji, F Yang, L Di Stefano, A Herr, NS Moon, EJ Kwon, ... Nature 455 (7212), 552-556, 2008 | 341 | 2008 |
| G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis DS Park, EJ Morris, LA Greene, HM Geller Journal of Neuroscience 17 (4), 1256-1270, 1997 | 336 | 1997 |
| Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents DS Park, EJ Morris, J Padmanabhan, ML Shelanski, HM Geller, ... The Journal of cell biology 143 (2), 457-467, 1998 | 330 | 1998 |
| Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress DS Park, EJ Morris, L Stefanis, CM Troy, ML Shelanski, HM Geller, ... Journal of Neuroscience 18 (3), 830-840, 1998 | 300 | 1998 |
| l‐DOPA Cytotoxicity to PC12 Cells in Culture Is via Its Autoxidation AN Basma, EJ Morris, WJ Nicklas, HM Geller Journal of neurochemistry 64 (2), 825-832, 1995 | 296 | 1995 |
| E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3 A Giovanni, E Keramaris, EJ Morris, ST Hou, M O'Hare, N Dyson, ... Journal of Biological Chemistry 275 (16), 11553-11560, 2000 | 246 | 2000 |
| Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage DS Park, EJ Morris, R Bremner, E Keramaris, J Padmanabhan, ... Journal of Neuroscience 20 (9), 3104-3114, 2000 | 181 | 2000 |
| Induction and modulation of cerebellar granule neuron death by E2F-1 MJ O'Hare, ST Hou, EJ Morris, SP Cregan, Q Xu, RS Slack, DS Park Journal of Biological Chemistry 275 (33), 25358-25364, 2000 | 171 | 2000 |
| Combining BH3-mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemia DM Moujalled, G Pomilio, C Ghiurau, A Ivey, J Salmon, S Rijal, S Macraild, ... Leukemia 33 (4), 905-917, 2019 | 167 | 2019 |
| Oxidative stress mediates neuronal DNA damage and apoptosis in response to cytosine arabinoside HM Geller, KY Cheng, NK Goldsmith, AA Romero, AL Zhang, EJ Morris, ... Journal of neurochemistry 78 (2), 265-275, 2001 | 151 | 2001 |
| Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo EJ Morris, WA Michaud, JY Ji, NS Moon, JW Rocco, NJ Dyson PLoS genetics 2 (11), e196, 2006 | 142 | 2006 |
| Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage EJ Morris, E Keramaris, HJ Rideout, RS Slack, NJ Dyson, L Stefanis, ... Journal of Neuroscience 21 (14), 5017-5026, 2001 | 131 | 2001 |
| Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2 O Stevaux, D Dimova, MV Frolov, B Taylor‐Harding, E Morris, N Dyson The EMBO journal, 2002 | 119 | 2002 |
| S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth P Casara, J Davidson, A Claperon, G Le Toumelin-Braizat, M Vogler, ... Oncotarget 9 (28), 20075, 2018 | 94 | 2018 |
| Reduced mitochondrial apoptotic priming drives resistance to BH3 mimetics in acute myeloid leukemia S Bhatt, MS Pioso, EA Olesinski, B Yilma, JA Ryan, T Mashaka, B Leutz, ... Cancer cell 38 (6), 872-890. e6, 2020 | 85 | 2020 |
| Drosophila E2F1 has context-specific pro-and antiapoptotic properties during development NS Moon, MV Frolov, EJ Kwon, L Di Stefano, DK Dimova, EJ Morris, ... Developmental cell 9 (4), 463-475, 2005 | 80 | 2005 |
| Dissecting therapeutic resistance to ERK inhibition S Jha, EJ Morris, A Hruza, MS Mansueto, GK Schroeder, J Arbanas, ... Molecular cancer therapeutics 15 (4), 548-559, 2016 | 68 | 2016 |
