Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites X Zhang, OO Coker, ESH Chu, K Fu, HCH Lau, YX Wang, AWH Chan, ... Gut 70 (4), 761-774, 2021 | 582 | 2021 |
High-fat diet promotes colorectal tumorigenesis through modulating gut microbiota and metabolites J Yang, H Wei, Y Zhou, CH Szeto, C Li, Y Lin, OO Coker, HCH Lau, ... Gastroenterology 162 (1), 135-149. e2, 2022 | 317 | 2022 |
Gastric microbes associated with gastric inflammation, atrophy and intestinal metaplasia 1 year after Helicobacter pylori eradication JJY Sung, OO Coker, E Chu, CH Szeto, STY Luk, HCH Lau, J Yu Gut 69 (9), 1572-1581, 2020 | 212 | 2020 |
Organoid models of gastrointestinal cancers in basic and translational research HCH Lau, O Kranenburg, H Xiao, J Yu Nature reviews Gastroenterology & hepatology 17 (4), 203-222, 2020 | 169 | 2020 |
Lactobacillus gallinarum modulates the gut microbiota and produces anti-cancer metabolites to protect against colorectal tumourigenesis N Sugimura, Q Li, ESH Chu, HCH Lau, W Fong, W Liu, C Liang, ... Gut 71 (10), 2011-2021, 2022 | 166 | 2022 |
Cancer pharmacomicrobiomics: targeting microbiota to optimise cancer therapy outcomes NLN Ting, HCH Lau, J Yu Gut 71 (7), 1412-1425, 2022 | 150 | 2022 |
Microbial community heterogeneity within colorectal neoplasia and its correlation with colorectal carcinogenesis W Liu, X Zhang, H Xu, S Li, HCH Lau, Q Chen, B Zhang, L Zhao, H Chen, ... Gastroenterology 160 (7), 2395-2408, 2021 | 104 | 2021 |
Excess body weight: Novel insights into its roles in obesity comorbidities X Zhang, S Ha, HCH Lau, J Yu Seminars in cancer biology 92, 16-27, 2023 | 95 | 2023 |
Metagenomic sequencing for microbial DNA in human samples: emerging technological advances Y Shi, G Wang, HCH Lau, J Yu International journal of molecular sciences 23 (4), 2181, 2022 | 86 | 2022 |
Altered mycobiota signatures and enriched pathogenic Aspergillus rambellii are associated with colorectal cancer based on multicohort fecal metagenomic analyses Y Lin, HCH Lau, Y Liu, X Kang, Y Wang, NLN Ting, TNY Kwong, J Han, ... Gastroenterology 163 (4), 908-921, 2022 | 74 | 2022 |
Parvimonas micra promotes colorectal tumorigenesis and is associated with prognosis of colorectal cancer patients L Zhao, X Zhang, Y Zhou, K Fu, HCH Lau, TWY Chun, AHK Cheung, ... Oncogene 41 (36), 4200-4210, 2022 | 70 | 2022 |
Roseburia intestinalis generated butyrate boosts anti-PD-1 efficacy in colorectal cancer by activating cytotoxic CD8+ T cells X Kang, C Liu, Y Ding, Y Ni, F Ji, HCH Lau, L Jiang, JJY Sung, SH Wong, ... Gut 72 (11), 2112-2122, 2023 | 64 | 2023 |
Lactobacillus gallinarum-derived metabolites boost anti-PD1 efficacy in colorectal cancer by inhibiting regulatory T cells through modulating IDO1/Kyn/AHR axis W Fong, Q Li, F Ji, W Liang, HCH Lau, X Kang, W Liu, KKW To, Z Zuo, X Li, ... Gut 72 (12), 2272-2285, 2023 | 50 | 2023 |
Bone marrow‐derived macrophage contributes to fibrosing steatohepatitis through activating hepatic stellate cells J Han, X Zhang, JKC Lau, K Fu, HCH Lau, W Xu, ESH Chu, H Lan, J Yu The Journal of pathology 248 (4), 488-500, 2019 | 48 | 2019 |
Gut microbiota: impacts on gastrointestinal cancer immunotherapy HCH Lau, JJY Sung, J Yu Gut Microbes 13 (1), 1869504, 2021 | 43 | 2021 |
Gut microbiome in colorectal cancer: Clinical diagnosis and treatment Y Liu, HCH Lau, WY Cheng, J Yu Genomics, Proteomics & Bioinformatics 21 (1), 84-96, 2023 | 40 | 2023 |
Fecal microbial DNA markers serve for screening colorectal neoplasm in asymptomatic subjects JQ Liang, SH Wong, CH Szeto, ESH Chu, HC Lau, Y Chen, J Fang, J Yu, ... Journal of gastroenterology and hepatology 36 (4), 1035-1043, 2021 | 33 | 2021 |
Microbial metabolites in colorectal tumorigenesis and cancer therapy Y Liu, HCH Lau, J Yu Gut Microbes 15 (1), 2203968, 2023 | 26 | 2023 |
Uncovering 1058 novel human enteric DNA viruses through deep long-read third-generation sequencing and their clinical impact L Zhao, Y Shi, HCH Lau, W Liu, G Luo, G Wang, C Liu, Y Pan, Q Zhou, ... Gastroenterology 163 (3), 699-711, 2022 | 25 | 2022 |
Gastric Microbiota beyond H. pylori: An Emerging Critical Character in Gastric Carcinogenesis J Wen, HCH Lau, M Peppelenbosch, J Yu Biomedicines 9 (11), 1680, 2021 | 23 | 2021 |