Favipiravir at high doses has potent antiviral activity in SARS-CoV-2− infected hamsters, whereas hydroxychloroquine lacks activity SJF Kaptein, S Jacobs, L Langendries, L Seldeslachts, S Ter Horst, ... Proceedings of the National Academy of Sciences 117 (43), 26955-26965, 2020 | 280 | 2020 |
STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters R Boudewijns, HJ Thibaut, SJF Kaptein, R Li, V Vergote, L Seldeslachts, ... Nature communications 11 (1), 5838, 2020 | 275 | 2020 |
A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate L Sanchez-Felipe, T Vercruysse, S Sharma, J Ma, V Lemmens, ... Nature 590 (7845), 320-325, 2021 | 173 | 2021 |
Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines N Hernandez, G Bucciol, L Moens, J Le Pen, M Shahrooei, E Goudouris, ... Journal of Experimental Medicine 216 (9), 2057-2070, 2019 | 155 | 2019 |
Comparing infectivity and virulence of emerging SARS-CoV-2 variants in Syrian hamsters R Abdelnabi, R Boudewijns, CS Foo, L Seldeslachts, L Sanchez-Felipe, ... EBioMedicine 68, 2021 | 94 | 2021 |
A yellow fever–Zika chimeric virus vaccine candidate protects against Zika infection and congenital malformations in mice DB Kum, N Mishra, R Boudewijns, I Gladwyn-Ng, C Alfano, J Ma, ... npj Vaccines 3 (1), 56, 2018 | 44 | 2018 |
An affinity-enhanced, broadly neutralizing heavy chain–only antibody protects against SARS-CoV-2 infection in animal models B Schepens, L van Schie, W Nerinckx, K Roose, W Van Breedam, ... Science Translational Medicine 13 (621), eabi7826, 2021 | 42 | 2021 |
Antiviral treatment of SARS-CoV-2-infected hamsters reveals a weak effect of favipiravir and a complete lack of effect for hydroxychloroquine SJF Kaptein, S Jacobs, L Langendries, L Seldeslachts, S ter Horst, ... BioRxiv, 2020.06. 19.159053, 2020 | 30 | 2020 |
A chimeric Japanese encephalitis vaccine protects against lethal yellow fever virus infection without inducing neutralizing antibodies N Mishra, R Boudewijns, MA Schmid, RE Marques, S Sharma, J Neyts, ... MBio 11 (2), 10.1128/mbio. 02494-19, 2020 | 28 | 2020 |
Itraconazole for COVID-19: preclinical studies and a proof-of-concept randomized clinical trial L Liesenborghs, I Spriet, D Jochmans, A Belmans, I Gyselinck, ... EBioMedicine 66, 2021 | 26 | 2021 |
SARS‐CoV‐2 surveillance in Norway rats (Rattus norvegicus) from Antwerp sewer system, Belgium VC Colombo, V Sluydts, J Mariën, B Vanden Broecke, N Van Houtte, ... Transboundary and Emerging Diseases 69 (5), 3016-3021, 2022 | 25 | 2022 |
A chimeric yellow fever-Zika virus vaccine candidate fully protects against yellow fever virus infection in mice DB Kum, R Boudewijns, J Ma, N Mishra, D Schols, J Neyts, K Dallmeier Emerging microbes & infections 9 (1), 520-533, 2020 | 22 | 2020 |
The pulmonary vasculature in lethal COVID-19 and idiopathic pulmonary fibrosis at single-cell resolution LPMH De Rooij, LM Becker, LA Teuwen, B Boeckx, S Jansen, S Feys, ... Cardiovascular research 119 (2), 520-535, 2023 | 18 | 2023 |
MVA-CoV2-S vaccine candidate neutralizes distinct variants of concern and protects against SARS-CoV-2 infection in hamsters R Boudewijns, P Pérez, A Lázaro-Frías, D Van Looveren, T Vercruysse, ... Frontiers in Immunology 13, 845969, 2022 | 18 | 2022 |
Comparative infectivity and pathogenesis of emerging SARS-CoV-2 variants in Syrian hamsters R Abdelnabi, R Boudewijns, CS Foo, L Seldeslachts, L Sanchez-Felipe, ... Biorxiv, 2021.02. 26.433062, 2021 | 17 | 2021 |
The SARS-CoV-2 Alpha variant exhibits comparable fitness to the D614G strain in a Syrian hamster model M Cochin, L Luciani, F Touret, JS Driouich, PR Petit, G Moureau, ... Communications Biology 5 (1), 225, 2022 | 15 | 2022 |
Comparing infectivity and virulence of emerging SARS-CoV-2 variants in Syrian hamsters. EBioMedicine 68: 103403 R Abdelnabi, R Boudewijns, CS Foo, L Seldeslachts, L Sanchez-Felipe, ... | 11 | 2021 |
STAT2 signaling as double-edged sword restricting viral dissemination but driving severe pneumonia in SARS-CoV-2 infected hamsters. bioRxiv. 2020 R Boudewijns, HJ Thibaut, SJF Kaptein, R Li, V Vergote, J Seldeslachts, ... Preprint. https://doi. org/10.1101/2020.04 23, 2020 | 11 | 2020 |
A novel therapeutic HBV vaccine candidate induces strong polyfunctional cytotoxic T cell responses in mice R Boudewijns, J Ma, J Neyts, K Dallmeier Jhep Reports 3 (4), 100295, 2021 | 9 | 2021 |
A SCID mouse model to evaluate the efficacy of antivirals against SARS-CoV-2 infection R Abdelnabi, CS Foo, SJF Kaptein, R Boudewijns, L Vangeel, ... Journal of Virology 96 (16), e00758-22, 2022 | 7 | 2022 |