Myofibroblasts in macular fibrosis secondary to neovascular age-related macular degeneration-the potential sources and molecular cues for their recruitment and activation K Little, JH Ma, N Yang, M Chen, H Xu EBioMedicine 38, 283-291, 2018 | 90 | 2018 |
Macrophage to myofibroblast transition contributes to subretinal fibrosis secondary to neovascular age-related macular degeneration K Little, M Llorián-Salvador, M Tang, X Du, S Marry, M Chen, H Xu Journal of neuroinflammation 17, 1-12, 2020 | 65 | 2020 |
Common pathways in dementia and diabetic retinopathy: understanding the mechanisms of diabetes-related cognitive decline K Little, M Llorián-Salvador, S Scullion, C Hernández, O Simó-Servat, ... Trends in Endocrinology & Metabolism 33 (1), 50-71, 2022 | 43 | 2022 |
Complement activation contributes to subretinal fibrosis through the induction of epithelial-to-mesenchymal transition (EMT) in retinal pigment epithelial cells M Llorián-Salvador, EM Byrne, M Szczepan, K Little, M Chen, H Xu Journal of neuroinflammation 19 (1), 182, 2022 | 20 | 2022 |
A two-stage laser-induced mouse model of subretinal fibrosis secondary to choroidal neovascularization K Little, M Llorián-Salvador, M Tang, X Du, Ó O'Shaughnessy, ... Translational Vision Science & Technology 9 (4), 3-3, 2020 | 16 | 2020 |
Deletion of Socs3 in LysM+ cells and Cx3cr1 resulted in age-dependent development of retinal microgliopathy X Du, R Penalva, K Little, A Kissenpfennig, M Chen, H Xu Molecular neurodegeneration 16, 1-17, 2021 | 12 | 2021 |
Myofibroblasts in macular fibrosis secondary to nAMD–the potential sources and molecular cues for their recruitment and activation K Little EBioMedicine 38, 283-91, 2018 | 5 | 2018 |
Targeting plasma kallikrein with a novel bicyclic peptide inhibitor (THR-149) reduces retinal thickening in a diabetic rat model T Van Bergen, TT Hu, K Little, L De Groef, L Moons, AW Stitt, ... Investigative ophthalmology & visual science 62 (13), 18-18, 2021 | 4 | 2021 |
Disruption of cortical cell type composition and function underlies diabetes-associated cognitive decline K Little, A Singh, A Del Marco, M Llorián-Salvador, M Vargas-Soria, ... Diabetologia 66 (8), 1557-1575, 2023 | 2 | 2023 |
Aldehyde Dehydrogenase and Aldo-Keto Reductase Enzymes: Basic Concepts and Emerging Roles in Diabetic Retinopathy BM Karan, K Little, J Augustine, AW Stitt, TM Curtis Antioxidants 12 (7), 1466, 2023 | 2 | 2023 |
Complement C5a induced epithelium to mesenchymal transition (EMT) in retinal pigment epithelial cells M Llorian-Salvador, EM Byrne, K Little, M Chen, H Xu Investigative Ophthalmology & Visual Science 61 (7), 1116-1116, 2020 | 1 | 2020 |
Characterising retinal neurovascular dysfunction in a mouse model of Alzheimer’s disease combined with Type 2 diabetes K Little, M Llorián-Salvador, Á del Marco, M Garcia-Alloza, R Simó, ... Investigative Ophthalmology & Visual Science 63 (7), 271–F0316-271–F0316, 2022 | | 2022 |
Retinal Neurovascular Dysfunction in a Mouse Model of Alzheimer's Disease Combined with Type 2 Diabetes K Little, M Llorian-Salvador, A del Marco, M Garcia-Alloza, R Simo, A Stitt EUROPEAN JOURNAL OF OPHTHALMOLOGY 32 (1_ SUPPL), 3-3, 2022 | | 2022 |
Complement C5a induced Epithelium to Mesenchymal Transition (EMT) in retinal pigment epithelial cells ML Salvador, EM Byrne, K Little, M Chen, H Xu Complement C5a induced Epithelium to Mesenchymal Transition (EMT) in retinal …, 2020 | | 2020 |
Investigating the role of the complement system in the pathogenesis of sub-retinal fibrosis in neovascular Age related Macular Degeneration K Little Queen's University Belfast, 2020 | | 2020 |
A two-stage laser induced model of sub-retinal fibrosis K Little, M Llorian-Salvador, M Chen, H Xu Investigative Ophthalmology & Visual Science 60 (9), 1263-1263, 2019 | | 2019 |
Complement C3a Induces Macrophage to Myofibroblast Transition (MMT) in Sub-retinal Fibrosis Secondary to Neovascular Age-Related Macular Degeneration K Little, M Chen, H Xu Investigative Ophthalmology & Visual Science 59 (9), 5552-5552, 2018 | | 2018 |