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Kuoyuan Cheng
Kuoyuan Cheng
MSD
Verified email at merck.com
Title
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Cited by
Year
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
L Riva, S Yuan, X Yin, L Martin-Sancho, N Matsunaga, L Pache, ...
Nature 586 (7827), 113-119, 2020
7262020
Identification of bacteria-derived HLA-bound peptides in melanoma
S Kalaora, A Nagler, D Nejman, M Alon, C Barbolin, E Barnea, ...
Nature 592 (7852), 138-143, 2021
2212021
Harnessing synthetic lethality to predict the response to cancer treatment
JS Lee, A Das, L Jerby-Arnon, R Arafeh, N Auslander, M Davidson, ...
Nature communications 9 (1), 2546, 2018
1162018
Novel mechanisms for superoxide-scavenging activity of human manganese superoxide dismutase determined by the K68 key acetylation site
J Lu, K Cheng, B Zhang, H Xu, Y Cao, F Guo, X Feng, Q Xia
Free Radical Biology and Medicine 85, 114-126, 2015
532015
In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression
S Sinha, K Cheng, AA Schäffer, K Aldape, E Schiff, E Ruppin
Molecular systems biology 16 (7), e9628, 2020
522020
Identification of drugs associated with reduced severity of COVID-19–a case-control study in a large population
A Israel, AA Schäffer, A Cicurel, K Cheng, S Sinha, E Schiff, I Feldhamer, ...
Elife 10, e68165, 2021
402021
A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing
S Sinha, K Barbosa, K Cheng, MDM Leiserson, P Jain, A Deshpande, ...
Nature communications 12 (1), 6512, 2021
392021
Genome‐scale metabolic modeling reveals SARS‐CoV‐2‐induced metabolic changes and antiviral targets
K Cheng, L Martin‐Sancho, LR Pal, Y Pu, L Riva, X Yin, S Sinha, NU Nair, ...
Molecular systems biology 17 (11), e10260, 2021
30*2021
Genome‐wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy
AD Sahu, J S Lee, Z Wang, G Zhang, R Iglesias‐Bartolome, T Tian, Z Wei, ...
Molecular systems biology 15 (3), e8323, 2019
292019
Systematic Cell Line-Based Identification of Drugs Modifying ACE2 Expression
S Sinha, K Cheng, K Aldape, E Schiff, E Ruppin
MDPI AG, 2020
252020
Berberine regulates neurite outgrowth through AMPK-dependent pathways by lowering energy status
J Lu, Y Cao, K Cheng, B Xu, T Wang, Q Yang, Q Yang, X Feng, Q Xia
Experimental cell research 334 (2), 194-206, 2015
252015
Large population study identifies drugs associated with reduced COVID-19 severity
A Israel, AA Schäffer, A Cicurel, I Feldhamer, A Tal, K Cheng, S Sinha, ...
MedRxiv, 2020
202020
Synthetic lethality across normal tissues is strongly associated with cancer risk, onset, and tumor suppressor specificity
K Cheng, NU Nair, JS Lee, E Ruppin
Science advances 7 (1), eabc2100, 2021
132021
Combinatorial detection of conserved alteration patterns for identifying cancer subnetworks
E Hodzic, R Shrestha, K Zhu, K Cheng, CC Collins, S Cenk Sahinalp
GigaScience 8 (4), giz024, 2019
92019
Cross-species identification of cancer resistance–associated genes that may mediate human cancer risk
NU Nair, K Cheng, L Naddaf, E Sharon, LR Pal, PS Rajagopal, ...
Science Advances 8 (31), eabj7176, 2022
72022
Synthetic lethality-based prediction of anti-SARS-CoV-2 targets
LR Pal, K Cheng, NU Nair, L Martin-Sancho, S Sinha, Y Pu, L Riva, X Yin, ...
Iscience 25 (5), 2022
62022
MnTM‐4‐PyP modulates endogenous antioxidant responses and protects primary cortical neurons against oxidative stress
KY Cheng, F Guo, JQ Lu, YZ Cao, TC Wang, Q Yang, Q Xia
CNS Neuroscience & Therapeutics 21 (5), 435-445, 2015
62015
Using a recently approved tumor mutational burden biomarker to stratify patients for immunotherapy may introduce a sex bias
N Sinha, S Sinha, K Cheng, S Madan, A Erez, BM Ryan, AA Schäffer, ...
JCO precision oncology 5, 2021
42021
Integrated computational and experimental identification of p53, KRAS and VHL mutant selection associated with CRISPR-Cas9 editing
S Sinha, KB Guerra, K Cheng, MDM Leiserson, DM Wilson III, BM Ryan, ...
bioRxiv, 407767, 2018
42018
Author Correction: A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing
S Sinha, K Barbosa, K Cheng, MDM Leiserson, P Jain, A Deshpande, ...
Nature Communications 13, 2022
22022
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