Modulators of CXCR4 and CXCR7/ACKR3 function I Adlere, B Caspar, M Arimont, S Dekkers, K Visser, J Stuijt, C de Graaf, ... Molecular pharmacology 96 (6), 737-752, 2019 | 57 | 2019 |
CRISPR-mediated protein tagging with nanoluciferase to investigate native chemokine receptor function and conformational changes CW White, B Caspar, HK Vanyai, KDG Pfleger, SJ Hill Cell chemical biology 27 (5), 499-510. e7, 2020 | 56 | 2020 |
Context-dependent signaling of CXC chemokine receptor 4 and atypical chemokine receptor 3 J Heuninck, CP Viciano, A Işbilir, B Caspar, D Capoferri, SJ Briddon, ... Molecular Pharmacology 96 (6), 778-793, 2019 | 35 | 2019 |
CXCR4/ACKR3 phosphorylation and recruitment of interacting proteins: key mechanisms regulating their functional status A Fumagalli, A Zarca, M Neves, B Caspar, SJ Hill, F Mayor, MJ Smit, ... Molecular pharmacology 96 (6), 794-808, 2019 | 19 | 2019 |
Kinetic analysis of the early signaling steps of the human chemokine receptor CXCR4 C Perpiñá-Viciano, A Işbilir, A Zarca, B Caspar, LE Kilpatrick, SJ Hill, ... Molecular Pharmacology 98 (2), 72-87, 2020 | 18 | 2020 |
Modulation of the allosteric communication between the polo-box domain and the catalytic domain in Plk1 by small compounds M Raab, M Sanhaji, L Pietsch, I Béquignon, AK Herbrand, E Süß, ... ACS chemical biology 13 (8), 1921-1931, 2018 | 17 | 2018 |
Structure-based exploration and pharmacological evaluation of N-substituted piperidin-4-yl-methanamine CXCR4 chemokine receptor antagonists I Adlere, S Sun, A Zarca, L Roumen, M Gozelle, CP Viciano, B Caspar, ... European journal of medicinal chemistry 162, 631-649, 2019 | 16 | 2019 |
CXCR4 as a novel target in immunology: moving away from typical antagonists B Caspar, P Cocchiara, A Melet, K Van Emelen, A Van der Aa, G Milligan, ... Future Drug Discovery 4 (2), FDD77, 2022 | 9 | 2022 |
A nuclear export sequence promotes CRM1-dependent targeting of the nucleoporin Nup214 to the nuclear pore complex M Hamed, B Caspar, SA Port, RH Kehlenbach Journal of cell science 134 (6), jcs258095, 2021 | 7 | 2021 |
Small-Molecule Fluorescent Ligands for the CXCR4 Chemokine Receptor S Dekkers, B Caspar, J Goulding, ND Kindon, LE Kilpatrick, LA Stoddart, ... Journal of Medicinal Chemistry 66 (7), 5208-5222, 2023 | 5 | 2023 |
Spermine and spermidine bind CXCR4 and inhibit CXCR4-but not CCR5-tropic HIV-1 infection M Harms, N Smith, M Han, R Groß, P Von Maltitz, C Stürzel, ... Science Advances 9 (27), eadf8251, 2023 | 4 | 2023 |
Small Molecule Fluorescent Ligands for the Atypical Chemokine Receptor 3 (ACKR3) S Dekkers, D Comez, N Karsai, M Arimont-Segura, M Canals, B Caspar, ... ACS medicinal chemistry letters 15 (1), 143-148, 2023 | 2 | 2023 |
Investigating the mode of action of intracellular loop 1 pepducins at the CXCR4 receptor B Caspar University of Nottingham, 2019 | | 2019 |