Glioblastoma-derived extracellular vesicles facilitate transformation of astrocytes via reprogramming oncogenic metabolism A Zeng, Z Wei, R Rabinovsky, HJ Jun, R El Fatimy, E Deforzh, R Arora, ... Iscience 23 (8), 2020 | 33 | 2020 |
Promoter and enhancer RNAs regulate chromatin reorganization and activation of miR-10b/HOXD locus, and neoplastic transformation in glioma E Deforzh, EJ Uhlmann, E Das, A Galitsyna, R Arora, H Saravanan, ... Molecular cell 82 (10), 1894-1908. e5, 2022 | 19 | 2022 |
IMP-3 protects the mRNAs of cyclins D1 and D3 from GW182/AGO2-dependent translational repression E Deforzh, TR Vargas, J Kropp, M Vandamme, G Pinna, A Polesskaya International Journal of Oncology 49 (6), 2578-2588, 2016 | 14 | 2016 |
The WEE1 regulators CPEB1 and miR-15b switch from inhibitor to activators at G2/M G Kratassiouk, LL Pritchard, S Cuvellier, A Vislovukh, Q Meng, ... Cell Cycle 15 (5), 667-677, 2016 | 12 | 2016 |
A nuclear function for an oncogenic microRNA as a modulator of snRNA and splicing R El Fatimy, Y Zhang, E Deforzh, M Ramadas, H Saravanan, Z Wei, ... Molecular Cancer 21 (1), 17, 2022 | 10 | 2022 |
Secreted PGK1 and IGFBP2 contribute to the bystander effect of miR-10b gene editing in glioma Y Zhang, R Rabinovsky, Z Wei, R El Fatimy, E Deforzh, B Luan, L Peshkin, ... Molecular Therapy-Nucleic Acids 31, 265-275, 2023 | 2 | 2023 |
Exploration of the Noncoding Genome for Human-Specific Therapeutic Targets—Recent Insights at Molecular and Cellular Level W Poller, S Sahoo, R Hajjar, U Landmesser, AM Krichevsky Cells 12 (22), 2660, 2023 | 1 | 2023 |
HOXDeRNA activates a cancerous transcription program and super-enhancers genome-wide E Deforzh, P Kharel, A Karelin, P Ivanov, AM Krichevsky bioRxiv, 2023 | 1 | 2023 |
Inhibition of the epigenetically activated miR-483-5p/IGF-2 pathway results in rapid loss of meningioma tumor cell viability EJ Uhlmann, CE Mackel, E Deforzh, R Rabinovsky, PK Brastianos, ... Journal of Neuro-oncology 162 (1), 109-118, 2023 | 1 | 2023 |
302 Targeted Inhibition of the Epigenetically Activated miR-483-5p IGF-2 Pathway as a Novel Therapeutic Strategy for Meningioma E Uhlmann, CE Mackel, E Deforzh, R Rabinovsky, P Brastianos, H Varma, ... Neurosurgery 70 (Supplement_1), 87, 2024 | | 2024 |
THE EPIGENETIC CIRCUIT OF HOXDERNA LONG NON-CODING RNA (LNCRNA) ACTIVATES GLIOBLASTOMA-SPECIFIC TRANSCRIPTION PROGRAMS AND SUPER-ENHANCERS GENOME-WIDE, SHAPING GLIAL CELL FATE … E Deforzh, P Kharel, P Ivanov, A Karelin, E Uhlmann, A Krichevsky NEURO-ONCOLOGY 25, 2023 | | 2023 |
THE IGF-2 SIGNALING PATHWAY IS A PROMISING MENINGIOMA TREATMENT TARGET E Uhlmann, R Rabinovsky, C Mackel, E Deforzh, R Vega, H Varma, ... NEURO-ONCOLOGY 25, 2023 | | 2023 |