A global genetic interaction network maps a wiring diagram of cellular function M Costanzo, B VanderSluis, EN Koch, A Baryshnikova, C Pons, G Tan, ... Science 353 (6306), aaf1420, 2016 | 1186 | 2016 |
Evaluation and design of genome-wide CRISPR/SpCas9 knockout screens T Hart, AHY Tong, K Chan, J Van Leeuwen, A Seetharaman, M Aregger, ... G3: Genes, Genomes, Genetics 7 (8), 2719-2727, 2017 | 457 | 2017 |
Systematic analysis of complex genetic interactions E Kuzmin, B VanderSluis, W Wang, G Tan, R Deshpande, Y Chen, M Usaj, ... Science 360 (6386), eaao1729, 2018 | 259 | 2018 |
Exploring genetic suppression interactions on a global scale J Van Leeuwen, C Pons, JC Mellor, TN Yamaguchi, H Friesen, ... Science 354 (6312), aag0839, 2016 | 183 | 2016 |
SGAtools: one-stop analysis and visualization of array-based genetic interaction screens O Wagih, M Usaj, A Baryshnikova, B VanderSluis, E Kuzmin, M Costanzo, ... Nucleic acids research 41 (W1), W591-W596, 2013 | 157 | 2013 |
TheCellMap. org: a web-accessible database for visualizing and mining the global yeast genetic interaction network M Usaj, Y Tan, W Wang, B VanderSluis, A Zou, CL Myers, M Costanzo, ... G3: Genes, genomes, genetics 7 (5), 1539-1549, 2017 | 135 | 2017 |
Essential gene profiles for human pluripotent stem cells identify uncharacterized genes and substrate dependencies B Mair, J Tomic, SN Masud, P Tonge, A Weiss, M Usaj, AHY Tong, ... Cell reports 27 (2), 599-615. e12, 2019 | 96 | 2019 |
Exploring whole-genome duplicate gene retention with complex genetic interaction analysis E Kuzmin, B VanderSluis, AN Nguyen Ba, W Wang, EN Koch, M Usaj, ... Science 368 (6498), eaaz5667, 2020 | 82 | 2020 |
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism M Aregger, KA Lawson, M Billmann, M Costanzo, AHY Tong, K Chan, ... Nature metabolism 2 (6), 499-513, 2020 | 72 | 2020 |
A global genetic interaction network maps a wiring diagram of cellular function. Science 353: aaf1420 M Costanzo, B VanderSluis, EN Koch, A Baryshnikova, C Pons, G Tan, ... | 56 | 2016 |
Environmental robustness of the global yeast genetic interaction network M Costanzo, J Hou, V Messier, J Nelson, M Rahman, B VanderSluis, ... Science 372 (6542), eabf8424, 2021 | 44 | 2021 |
Systematic genetics and single‐cell imaging reveal widespread morphological pleiotropy and cell‐to‐cell variability M Mattiazzi Usaj, N Sahin, H Friesen, C Pons, M Usaj, MPD Masinas, ... Molecular systems biology 16 (2), e9243, 2020 | 44 | 2020 |
A genome‐scale yeast library with inducible expression of individual genes Y Arita, G Kim, Z Li, H Friesen, G Turco, RY Wang, D Climie, M Usaj, ... Molecular Systems Biology 17 (6), e10207, 2021 | 42 | 2021 |
Systematic analysis of bypass suppression of essential genes J Van Leeuwen, C Pons, G Tan, JZ Wang, J Hou, J Weile, M Gebbia, ... Molecular systems biology 16 (9), e9828, 2020 | 40 | 2020 |
A cohesin traffic pattern genetically linked to gene regulation AL Valton, SV Venev, B Mair, ES Khokhar, AHY Tong, M Usaj, K Chan, ... Nature structural & molecular biology 29 (12), 1239-1251, 2022 | 33 | 2022 |
Exploring quantitative yeast phenomics with single-cell analysis of DNA damage foci EB Styles, KJ Founk, LA Zamparo, TL Sing, D Altintas, C Ribeyre, ... Cell systems 3 (3), 264-277. e10, 2016 | 31 | 2016 |
N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity S Varland, RD Silva, I Kjosås, A Faustino, A Bogaert, M Billmann, ... Nature communications 14 (1), 6774, 2023 | 14 | 2023 |
Environmental robustness of the global yeast genetic interaction network. Science 372, eabf8424 M Costanzo, J Hou, V Messier, J Nelson, M Rahman, B VanderSluis, ... | 5 | 2021 |
TheCellVision. org: a database for visualizing and mining high-content cell imaging projects MPD Masinas, MM Usaj, M Usaj, C Boone, BJ Andrews G3: Genes, Genomes, Genetics 10 (11), 3969-3976, 2020 | 4 | 2020 |
Exploring endocytic compartment morphology with systematic genetics and single cell image analysis MM Usaj, N Sahin, H Friesen, C Pons, M Usaj, MP Masinas, E Shuteriqi, ... BioRxiv, 724989, 2019 | 2 | 2019 |