Genomic profiling of childhood tumor patient-derived xenograft models to enable rational clinical trial design JL Rokita, KS Rathi, MF Cardenas, KA Upton, J Jayaseelan, KL Cross, ... Cell reports 29 (6), 1675-1689. e9, 2019 | 153 | 2019 |
FAS-antisense 1 lncRNA and production of soluble versus membrane Fas in B-cell lymphoma L Sehgal, R Mathur, FK Braun, JF Wise, Z Berkova, S Neelapu, LW Kwak, ... Leukemia 28 (12), 2376-2387, 2014 | 151 | 2014 |
Nucleolin inhibits Fas ligand binding and suppresses Fas-mediated apoptosis in vivo via a surface nucleolin-Fas complex JF Wise, Z Berkova, R Mathur, H Zhu, FK Braun, RH Tao, AL Sabichi, ... Blood, The Journal of the American Society of Hematology 121 (23), 4729-4739, 2013 | 88 | 2013 |
Tumor suppressor TNFAIP3 (A20) is frequently deleted in Sezary syndrome FCM Braun, P Grabarczyk, M Möbs, FK Braun, J Eberle, M Beyer, ... Leukemia 25 (9), 1494-1501, 2011 | 69 | 2011 |
Enhanced death ligand-induced apoptosis in cutaneous SCC cells by treatment with diclofenac/hyaluronic acid correlates with downregulation of c-FLIP LF Fecker, E Stockfleth, FK Braun, PM Rodust, C Schwarz, A Köhler, ... Journal of Investigative Dermatology 130 (8), 2098-2109, 2010 | 67 | 2010 |
Apoptosis induction by SAHA in cutaneous T-cell lymphoma cells is related to downregulation of c-FLIP and enhanced TRAIL signaling N Al-Yacoub, LF Fecker, M Möbs, M Plötz, FK Braun, W Sterry, J Eberle Journal of investigative dermatology 132 (9), 2263-2274, 2012 | 65 | 2012 |
Systems biology–based drug repositioning identifies digoxin as a potential therapy for groups 3 and 4 medulloblastoma L Huang, S Garrett Injac, K Cui, F Braun, Q Lin, Y Du, H Zhang, M Kogiso, ... Science translational medicine 10 (464), eaat0150, 2018 | 64 | 2018 |
Immunomodulatory effects of sorafenib on peripheral immune effector cells in metastatic renal cell carcinoma A Busse, AM Asemissen, A Nonnenmacher, F Braun, S Ochsenreither, ... European Journal of Cancer 47 (5), 690-696, 2011 | 64 | 2011 |
Blockade of death receptor-mediated pathways early in the signaling cascade coincides with distinct apoptosis resistance in cutaneous T-cell lymphoma cells FK Braun, LF Fecker, C Schwarz, P Walden, C Assaf, H Dürkop, W Sterry, ... Journal of investigative dermatology 127 (10), 2425-2437, 2007 | 63 | 2007 |
Genetic rearrangements result in altered gene expression and novel fusion transcripts in Sézary syndrome GK Przybylski, C Gand, FC Braun, P Grabarczyk, AW Kuss, K Olek-Hrab, ... Oncotarget 8 (24), 39627, 2017 | 51 | 2017 |
Targeting Wnt pathway in mantle cell lymphoma-initiating cells R Mathur, L Sehgal, FK Braun, Z Berkova, J Romaguerra, M Wang, ... Journal of hematology & oncology 8, 1-12, 2015 | 50 | 2015 |
Nonsteroidal anti-inflammatory drugs induce apoptosis in cutaneous T-cell lymphoma cells and enhance their sensitivity for TNF-related apoptosis-inducing ligand FK Braun, N Al-Yacoub, M Plötz, M Möbs, W Sterry, J Eberle Journal of Investigative Dermatology 132 (2), 429-439, 2012 | 43 | 2012 |
Resistance of cutaneous anaplastic large-cell lymphoma cells to apoptosis by death ligands is enhanced by CD30-mediated overexpression of c-FLIP FK Braun, B Hirsch, N Al-Yacoub, H Dürkop, C Assaf, ME Kadin, W Sterry, ... Journal of investigative dermatology 130 (3), 826-840, 2010 | 36 | 2010 |
Targeting nucleolin for better survival in diffuse large B-cell lymphoma N Jain, H Zhu, T Khashab, Q Ye, B George, R Mathur, RK Singh, ... Leukemia 32 (3), 663-674, 2018 | 35 | 2018 |
HMGB1 promotes mitochondrial dysfunction–triggered striatal neurodegeneration via autophagy and apoptosis activation L Qi, X Sun, FE Li, BS Zhu, FK Braun, ZQ Liu, JL Tang, C Wu, F Xu, ... PLoS One 10 (11), e0142901, 2015 | 31 | 2015 |
90Y‐ibritumomab tiuxetan radiotherapy as first‐line therapy for early stage low‐grade B‐cell lymphomas, including bulky disease F Samaniego, Z Berkova, JE Romaguera, N Fowler, MA Fanale, B Pro, ... British journal of haematology 167 (2), 207-213, 2014 | 30 | 2014 |
Concurrent inhibition of neurosphere and monolayer cells of pediatric glioblastoma by aurora A inhibitor MLN8237 predicted survival extension in PDOX models M Kogiso, L Qi, FK Braun, SG Injac, L Zhang, Y Du, H Zhang, FY Lin, ... Clinical Cancer Research 24 (9), 2159-2170, 2018 | 29 | 2018 |
Inhibition of methyltransferases accelerates degradation of cFLIP and sensitizes B-cell lymphoma cells to TRAIL-induced apoptosis FK Braun, R Mathur, L Sehgal, R Wilkie-Grantham, J Chandra, Z Berkova, ... PloS one 10 (3), e0117994, 2015 | 28 | 2015 |
Patient-derived orthotopic xenograft (PDOX) mouse models of primary and recurrent meningioma H Zhang, L Qi, Y Du, LF Huang, FK Braun, M Kogiso, Y Zhao, C Li, ... Cancers 12 (6), 1478, 2020 | 26 | 2020 |
Xenotransplantation of pediatric low grade gliomas confirms the enrichment of BRAF V600E mutation and preservation of CDKN2A deletion in a novel orthotopic xenograft mouse … M Kogiso, L Qi, H Lindsay, Y Huang, X Zhao, Z Liu, FK Braun, Y Du, ... Oncotarget 8 (50), 87455, 2017 | 23 | 2017 |