Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature C Kleinschnitz, P Kraft, A Dreykluft, I Hagedorn, K Göbel, MK Schuhmann, ... Blood, The Journal of the American Society of Hematology 121 (4), 679-691, 2013 | 392 | 2013 |
Myelin oligodendrocyte glycoprotein (MOG35-55) induced experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice S Bittner, AM Afzali, H Wiendl, SG Meuth Journal of visualized experiments: JoVE, 2014 | 302 | 2014 |
Alemtuzumab in multiple sclerosis: mechanism of action and beyond T Ruck, S Bittner, H Wiendl, SG Meuth International journal of molecular sciences 16 (7), 16414-16439, 2015 | 251 | 2015 |
Serum neurofilament light chain is a biomarker of acute and chronic neuronal damage in early multiple sclerosis N Siller, J Kuhle, M Muthuraman, C Barro, T Uphaus, S Groppa, L Kappos, ... Multiple Sclerosis Journal 25 (5), 678-686, 2019 | 217 | 2019 |
The potential of serum neurofilament as biomarker for multiple sclerosis S Bittner, J Oh, EK Havrdová, M Tintoré, F Zipp Brain 144 (10), 2954-2963, 2021 | 165 | 2021 |
Endothelial TWIK-related potassium channel-1 (TREK1) regulates immune-cell trafficking into the CNS S Bittner, T Ruck, MK Schuhmann, AM Herrmann, HMO Maati, N Bobak, ... Nature medicine 19 (9), 1161-1165, 2013 | 165 | 2013 |
TWIK-related acid-sensitive K+ channel 1 (TASK1) and TASK3 critically influence T lymphocyte effector functions SG Meuth, S Bittner, P Meuth, OJ Simon, T Budde, H Wiendl Journal of biological chemistry 283 (21), 14559-14570, 2008 | 131 | 2008 |
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells K Göbel, S Pankratz, CM Asaridou, AM Herrmann, S Bittner, M Merker, ... Nature communications 7 (1), 11626, 2016 | 128 | 2016 |
NfL (neurofilament light chain) levels as a predictive marker for long-term outcome after ischemic stroke T Uphaus, S Bittner, S Gröschel, F Steffen, M Muthuraman, K Wasser, ... Stroke 50 (11), 3077-3084, 2019 | 123 | 2019 |
Isolation of primary murine brain microvascular endothelial cells T Ruck, S Bittner, L Epping, AM Herrmann, SG Meuth Journal of visualized experiments: JoVE, 52204, 2014 | 123 | 2014 |
Stromal interaction molecules 1 and 2 are key regulators of autoreactive T cell activation in murine autoimmune central nervous system inflammation MK Schuhmann, D Stegner, A Berna-Erro, S Bittner, A Braun, ... The journal of immunology 184 (3), 1536-1542, 2010 | 123 | 2010 |
TASK1 modulates inflammation and neurodegeneration in autoimmune inflammation of the central nervous system S Bittner, SG Meuth, K Göbel, N Melzer, AM Herrmann, OJ Simon, ... Brain 132 (9), 2501-2516, 2009 | 121 | 2009 |
A β-lactam antibiotic dampens excitotoxic inflammatory CNS damage in a mouse model of multiple sclerosis N Melzer, SG Meuth, D Torres-Salazar, S Bittner, AL Zozulya, ... PLoS One 3 (9), e3149, 2008 | 112 | 2008 |
Multiple Sclerosis Therapy Consensus Group (MSTCG): position statement on disease-modifying therapies for multiple sclerosis (white paper) H Wiendl, R Gold, T Berger, T Derfuss, R Linker, M Mäurer, O Aktas, ... Therapeutic advances in neurological disorders 14, 17562864211039648, 2021 | 105 | 2021 |
Cytotoxic CD8+ T cell–neuron interactions: perforin-dependent electrical silencing precedes but is not causally linked to neuronal cell death SG Meuth, AM Herrmann, OJ Simon, V Siffrin, N Melzer, S Bittner, ... Journal of Neuroscience 29 (49), 15397-15409, 2009 | 105 | 2009 |
Transient receptor potential melastatin subfamily member 2 cation channel regulates detrimental immune cell invasion in ischemic stroke M Gelderblom, N Melzer, B Schattling, E Göb, G Hicking, P Arunachalam, ... Stroke 45 (11), 3395-3402, 2014 | 100 | 2014 |
Complete Epstein-Barr virus seropositivity in a large cohort of patients with early multiple sclerosis S Abrahamyan, B Eberspächer, MM Hoshi, L Aly, F Luessi, S Groppa, ... Journal of Neurology, Neurosurgery & Psychiatry 91 (7), 681-686, 2020 | 98 | 2020 |
Clinical implications of serum neurofilament in newly diagnosed MS patients: a longitudinal multicentre cohort study S Bittner, F Steffen, T Uphaus, M Muthuraman, V Fleischer, A Salmen, ... EBioMedicine 56, 2020 | 97 | 2020 |
Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis I Kleiter, J Song, D Lukas, M Hasan, B Neumann, AL Croxford, X Pedre, ... Brain 133 (4), 1067-1081, 2010 | 97 | 2010 |
Blocking of α4 integrin does not protect from acute ischemic stroke in mice F Langhauser, P Kraft, E Göb, J Leinweber, MK Schuhmann, K Lorenz, ... Stroke 45 (6), 1799-1806, 2014 | 96 | 2014 |