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Stephen C Becker PhD
Stephen C Becker PhD
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The phage K lytic enzyme LysK and lysostaphin act synergistically to kill MRSA
SC Becker, J Foster-Frey, DM Donovan
FEMS microbiology letters 287 (2), 185-191, 2008
2232008
Chimeric phage lysins act synergistically with lysostaphin to kill mastitis-causing Staphylococcus aureus in murine mammary glands
M Schmelcher, AM Powell, SC Becker, MJ Camp, DM Donovan
Applied and environmental microbiology 78 (7), 2297-2305, 2012
1972012
LysK CHAP endopeptidase domain is required for lysis of live staphylococcal cells
SC Becker, S Dong, JR Baker, J Foster-Frey, DG Pritchard, DM Donovan
FEMS microbiology letters 294 (1), 52-60, 2009
1802009
Evolutionarily distinct bacteriophage endolysins featuring conserved peptidoglycan cleavage sites protect mice from MRSA infection
M Schmelcher, Y Shen, DC Nelson, MR Eugster, F Eichenseher, ...
Journal of Antimicrobial Chemotherapy 70 (5), 1453-1465, 2015
1602015
Differentially conserved staphylococcal SH3b_5 cell wall binding domains confer increased staphylolytic and streptolytic activity to a streptococcal prophage endolysin domain
SC Becker, J Foster-Frey, AJ Stodola, D Anacker, DM Donovan
Gene 443 (1-2), 32-41, 2009
1402009
Triple-acting Lytic Enzyme Treatment of Drug-Resistant and Intracellular Staphylococcus aureus
SC Becker, DR Roach, VS Chauhan, Y Shen, J Foster-Frey, AM Powell, ...
Scientific reports 6 (1), 25063, 2016
952016
Staphylococcal Phage 2638A endolysin is lytic for Staphylococcus aureus and harbors an inter-lytic-domain secondary translational start site
I Abaev, J Foster-Frey, O Korobova, N Shishkova, N Kiseleva, P Kopylov, ...
Applied microbiology and biotechnology 97, 3449-3456, 2013
742013
Staphylococcal Phage 2638A endolysin is lytic for Staphylococcus aureus and harbors an inter-lytic-domain secondary translational start site
I Abaev, J Foster-Frey, O Korobova, N Shishkova, N Kiseleva, P Kopylov, ...
Applied microbiology and biotechnology 97, 3449-3456, 2013
742013
Lytic activity of the staphylolytic Twort phage endolysin CHAP domain is enhanced by the SH3b cell wall binding domain
SC Becker, S Swift, O Korobova, N Schischkova, P Kopylov, DM Donovan, ...
FEMS microbiology letters 362 (1), 1, 2015
622015
LysK, the enzyme lysing Staphylococcus aureus cells: specific kinetic features and approaches towards stabilization
LY Filatova, SC Becker, DM Donovan, AK Gladilin, NL Klyachko
Biochimie 92 (5), 507-513, 2010
522010
Functional characterization of the competence protein DprA/Smf in Escherichia coli
LC Smeets, SC Becker, GJ Barcak, CMJE Vandenbroucke-Grauls, ...
FEMS microbiology letters 263 (2), 223-228, 2006
352006
Peptidoglycan hydrolase enzyme fusions for treating multi-drug resistant pathogens
DM Donovan, SC Becker, S Dong, JR Baker, J Foster-Frey, DG Pritchard
332009
Physicochemical characterization of the staphylolytic LysK enzyme in complexes with polycationic polymers as a potent antimicrobial
LY Filatova, DM Donovan, SC Becker, DN Lebedev, AD Priyma, ...
Biochimie 95 (9), 1689-1696, 2013
312013
Physicochemical characterization of the staphylolytic LysK enzyme in complexes with polycationic polymers as a potent antimicrobial
LY Filatova, DM Donovan, SC Becker, DN Lebedev, AD Priyma, ...
Biochimie 95 (9), 1689-1696, 2013
312013
Characterization of TetD as a transcriptional activator of a subset of genes of the Escherichia coli SoxS/MarA/Rob regulon
KL Griffith, SM Becker, R E. Wolf Jr
Molecular microbiology 56 (4), 1103-1117, 2005
302005
A Chimeric LysK-Lysostaphin Fusion Enzyme Lysing Staphylococcus aureus Cells: a Study of Both Kinetics of Inactivation and Specifics of Interaction with Anionic …
LY Filatova, DM Donovan, NT Ishnazarova, JA Foster-Frey, SC Becker, ...
Applied biochemistry and biotechnology 180, 544-557, 2016
242016
Triple acting antimicrobials that are refractory to resistance development
DM Donovan, SC Becker
US Patent 8,481,289, 2013
122013
An investigation of the structure and function of antistaphylococcal endolysins using kinetic methods
LY Filatova, DM Donovan, SC Becker, AD Priyma, AV Kabanov, ...
Moscow University Chemistry Bulletin 69, 107-111, 2014
62014
Lys K endolysin is synergistic with lysostaphin against MRSA
DM Donovan, SC Becker
US Patent 8,568,714, 2013
62013
Polycation stabilization of the enzyme LysK lysing Staphylococcus Aureus cells
LY Filatova, SC Becker, DM Donovan, AK Gladilin, NL Klyachko
Moscow University Chemistry Bulletin 64, 382-384, 2009
42009
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