Caspase-11 mediates neutrophil chemotaxis and extracellular trap formation during acute gouty arthritis through alteration of cofilin phosphorylation K Caution, N Young, F Robledo-Avila, K Krause, A Abu Khweek, ... Frontiers in Immunology 10, 2519, 2019 | 62 | 2019 |
Elevated expression of MiR-17 in microglia of Alzheimer’s disease patients abrogates autophagy-mediated amyloid-β degradation S Estfanous, KP Daily, M Eltobgy, NP Deems, MNK Anne, K Krause, ... Frontiers in immunology 12, 705581, 2021 | 41 | 2021 |
Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo S Estfanous, K Krause, MNK Anne, M Eltobgy, K Caution, A Abu Khweek, ... Scientific reports 11 (1), 855, 2021 | 30 | 2021 |
Caspase‐11 counteracts mitochondrial ROS‐mediated clearance of Staphylococcus aureus in macrophages K Krause, K Daily, S Estfanous, K Hamilton, A Badr, A Abu Khweek, ... EMBO reports 20 (12), e48109, 2019 | 29 | 2019 |
Caspase-4/11 exacerbates disease severity in SARS–CoV-2 infection by promoting inflammation and immunothrombosis MM Eltobgy, A Zani, AD Kenney, S Estfanous, E Kim, A Badr, C Carafice, ... Proceedings of the National Academy of Sciences 119 (21), e2202012119, 2022 | 28 | 2022 |
Methylomic correlates of autophagy activity in cystic fibrosis K Caution, A Pan, K Krause, A Badr, K Hamilton, A Vaidya, H Gosu, ... Journal of Cystic Fibrosis 18 (4), 491-500, 2019 | 25 | 2019 |
Inflammasome genes’ polymorphisms in Egyptian chronic hepatitis C patients: influence on vulnerability to infection and response to treatment SZK Estfanous, SA Ali, SM Seif, SHA Soror, DHA Abdelaziz Mediators of inflammation 2019, 2019 | 22 | 2019 |
Uropathogenic Escherichia coli infection-induced epithelial trained immunity impacts urinary tract disease outcome SK Russell, JK Harrison, BS Olson, HJ Lee, VP O’Brien, X Xing, J Livny, ... Nature microbiology 8 (5), 875-888, 2023 | 15 | 2023 |
CFTR modulators restore acidification of autophago-lysosomes and bacterial clearance in cystic fibrosis macrophages A Badr, M Eltobgy, K Krause, K Hamilton, S Estfanous, KP Daily, ... Frontiers in Cellular and Infection Microbiology 12, 819554, 2022 | 13 | 2022 |
Defective immunometabolism pathways in cystic fibrosis macrophages K Hamilton, K Krause, A Badr, K Daily, S Estfanous, M Eltobgy, ... Journal of Cystic Fibrosis 20 (4), 664-672, 2021 | 7 | 2021 |
Caspase-11 regulates lung inflammation in response to house dust mites AA Khweek, MR Joldrichsen, E Kim, Z Attia, K Krause, K Daily, ... Cellular immunology 370, 104425, 2021 | 5 | 2021 |
Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and thrombosis M Eltobgy, A Zani, AD Kenney, S Estfanous, E Kim, A Badr, C Carafice, ... bioRxiv, 2021.09. 24.461743, 2021 | 4 | 2021 |
Author Correction: Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo S Estfanous, K Krause, MNK Anne, M Eltobgy, K Caution, AA Khweek, ... Scientific Reports 11 (1), 12447, 2021 | 2 | 2021 |
Elevated Expression of MiR-17 in Microglia of Alzheimer’s Disease Patients Abrogates Autophagy-Mediated Amyloid-b Degradation S Estfanous, KP Daily, M Eltobgy, NP Deems, MNK Anne, K Krause, ... Front. Immunol. 12: 705581. doi: 10.3389/fimmu, 2021 | 1 | 2021 |
Microglia-targeted inhibition of miR-17 via mannose-coated lipid nanoparticles improves pathology and behavior in a mouse model of Alzheimer’s disease A Badr, KP Daily, M Eltobgy, S Estfanous, MH Tan, JCT Kuo, O Whitham, ... Brain, Behavior, and Immunity, 2024 | | 2024 |
DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer’s disease KP Daily, A Badr, M Eltobgy, S Estfanous, O Whitham, MH Tan, C Carafice, ... Alzheimer's Research & Therapy 16 (1), 29, 2024 | | 2024 |
Bacterial infection drives trained immunity through epigenetic remodeling of epithelial stem cells S Hultgren, S Russell, HJ Lee, B Olson, J Livny, V O’Brien, L Yu, ... | | 2021 |
Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and thrombosis (preprint) M Eltobgy, A Zani, A Kenney, S Estfanous, E Kim, A Badr, C Carafice, ... | | 2021 |
CFTR MODULATORS-MEDIATED CORRECTION OF LYSOSOMAL DYSFUNCTION RESTORES AUTOPHAGY AND BACTERIAL CLEARANCE IN CF MACROPHAGES AA Badr, K Krause, M Eltobgy, K Hamilton, S Estfanous, A Abu Khweek, ... PEDIATRIC PULMONOLOGY 55, S140-S140, 2020 | | 2020 |
Can NLRP3 gene polymorphism in Egyptian chronic hepatitis C patients affect the degree of liver fibrosis? SZK Estfanous, SM Seif, SHA Soror, DHA Abdelaziz | | |