Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation VA Gerriets, RJ Kishton, AG Nichols, AN Macintyre, M Inoue, O Ilkayeva, ... The Journal of clinical investigation 125 (1), 194-207, 2015 | 666 | 2015 |
Targeting the Janus kinase family in autoimmune skin diseases MD Howell, FI Kuo, PA Smith Frontiers in immunology 10, 2342, 2019 | 183 | 2019 |
Targeting the Janus Kinase Family in Autoimmune Skin Diseases MD Howell, FI Kuo, PA Smith Frontiers in Immunology 10, 2019 | 183 | 2019 |
Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation F Bornancin, F Renner, R Touil, H Sic, Y Kolb, I Touil-Allaoui, JS Rush, ... The Journal of Immunology 194 (8), 3723-3734, 2015 | 137 | 2015 |
Pathological and regulatory effects of anti-myelin antibodies in experimental allergic encephalomyelitis in mice MM Morris-Downes, PA Smith, JL Rundle, SJ Piddlesden, D Baker, ... Journal of neuroimmunology 125 (1-2), 114-124, 2002 | 114 | 2002 |
Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945 N Beckmann, E Giorgetti, A Neuhaus, S Zurbruegg, N Accart, P Smith, ... Acta Neuropathologica Communications 6 (1), 9, 2018 | 113 | 2018 |
A potent and selective S1P 1 antagonist with efficacy in experimental autoimmune encephalomyelitis J Quancard, B Bollbuck, P Janser, D Angst, F Berst, P Buehlmayer, ... Chemistry & biology 19 (9), 1142-1151, 2012 | 113 | 2012 |
Cross-reactivity between related sequences found in Acinetobacter sp., Pseudomonas aeruginosa, myelin basic protein and myelin oligodendrocyte glycoprotein in multiple sclerosis LE Hughes, PA Smith, S Bonell, RS Natt, C Wilson, T Rashid, S Amor, ... Journal of neuroimmunology 144 (1), 105-115, 2003 | 104 | 2003 |
High incidence of spontaneous disease in an HLA-DR15 and TCR transgenic multiple sclerosis model S Ellmerich, M Mycko, K Takacs, H Waldner, FN Wahid, RJ Boyton, ... The Journal of Immunology 174 (4), 1938-1946, 2005 | 97 | 2005 |
Inhibition of cytokine signaling by ruxolitinib and implications for COVID-19 treatment S Yeleswaram, P Smith, T Burn, M Covington, A Juvekar, Y Li, P Squier, ... Clinical Immunology, 108517, 2020 | 94 | 2020 |
Biozzi mice: of mice and human neurological diseases S Amor, PA Smith, B Hart, D Baker Journal of neuroimmunology 165 (1), 1-10, 2005 | 89 | 2005 |
Disease‐related epitope spread in a humanized T cell receptor transgenic model of multiple sclerosis S Ellmerich, K Takacs, M Mycko, H Waldner, F Wahid, RJ Boyton, ... European journal of immunology 34 (7), 1839-1848, 2004 | 70 | 2004 |
JAK/STAT inhibitors and other small molecule cytokine antagonists for the treatment of allergic disease MD Howell, C Fitzsimons, P Smith Annals of Allergy, Asthma & Immunology, 2018 | 68 | 2018 |
Enhanced in vivo efficacy of a type I interferon superagonist with extended plasma half-life in a mouse model of multiple sclerosis D Harari, N Kuhn, R Abramovich, K Sasson, AL Zozulya, P Smith, ... Journal of Biological Chemistry 289 (42), 29014-29029, 2014 | 68 | 2014 |
Fast progression of recombinant human myelin/oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis in marmosets is associated with the activation … YS Kap, P Smith, SA Jagessar, E Remarque, E Blezer, GJ Strijkers, ... The Journal of Immunology 180 (3), 1326-1337, 2008 | 68 | 2008 |
Native myelin oligodendrocyte glycoprotein promotes severe chronic neurological disease and demyelination in Biozzi ABH mice PA Smith, N Heijmans, B Ouwerling, EC Breij, N Evans, JM van Noort, ... European journal of immunology 35 (4), 1311-1319, 2005 | 68 | 2005 |
Itacitinib (INCB039110), a JAK1 inhibitor, Reduces Cytokines Associated with Cytokine Release Syndrome Induced by CAR T-Cell Therapy E Huarte, RS O'Conner, MT Peel, S Nunez-Cruz, J Leferovich, A Juvekar, ... Clinical Cancer Research, 2020 | 63 | 2020 |
Bridging the species divide: transgenic mice humanized for type-I interferon response D Harari, R Abramovich, A Zozulya, P Smith, S Pouly, M Köster, H Hauser, ... PloS one 9 (1), e84259, 2014 | 56 | 2014 |
Bridging the species divide: transgenic mice humanized for type-I interferon response D Harari, R Abramovich, A Zozulya, P Smith, S Pouly, M Köster, H Hauser, ... PloS one 9 (1), e84259, 2014 | 56 | 2014 |
Autoimmunity against myelin oligodendrocyte glycoprotein is dispensable for the initiation although essential for the progression of chronic encephalomyelitis in common marmosets SA Jagessar, PA Smith, E Blezer, C Delarasse, D Pham-Dinh, JD Laman, ... Journal of Neuropathology & Experimental Neurology 67 (4), 326-340, 2008 | 52 | 2008 |