Exit fromdormancy provokes DNA-damage-induced attrition in haematopoietic stem cells D Walter, A Lier, A Geiselhart, FB Thalheimer, S Huntscha, MC Sobotta, ... Nature 520 (7548), 549, 2015 | 642 | 2015 |
CD133 positive embryonal rhabdomyosarcoma stem-like cell population is enriched in rhabdospheres D Walter, S Satheesha, P Albrecht, BC Bornhauser, V D'Alessandro, ... PloS one 6 (5), e19506, 2011 | 131 | 2011 |
Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging R Bogeska, AM Mikecin, P Kaschutnig, M Fawaz, M Büchler-Schäff, D Le, ... Cell stem cell 29 (8), 1273-1284. e8, 2022 | 100 | 2022 |
Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma S Oesch, D Walter, M Wachtel, K Pretre, M Salazar, M Guzmán, G Velasco, ... Molecular cancer therapeutics 8 (7), 1838-1845, 2009 | 62 | 2009 |
Stem cell-specific mechanisms ensure genomic fidelity within HSCs and upon aging of HSCs BM Moehrle, K Nattamai, A Brown, MC Florian, M Ryan, M Vogel, ... Cell reports 13 (11), 2412-2424, 2015 | 60 | 2015 |
p21 Downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment RM Hecker, RA Amstutz, M Wachtel, D Walter, FK Niggli, BW Schäfer Oncogene 29 (27), 3942-3952, 2010 | 32 | 2010 |
The Fanconi anemia pathway is required for efficient repair of stress-induced DNA damage in haematopoietic stem cells P Kaschutnig, R Bogeska, D Walter, A Lier, S Huntscha, MD Milsom Cell Cycle 14 (17), 2734-2742, 2015 | 25 | 2015 |
Disrupted signaling through the Fanconi anemia pathway leads to dysfunctional hematopoietic stem cell biology: underlying mechanisms and potential therapeutic strategies A Geiselhart, A Lier, D Walter, MD Milsom Anemia 2012, 2012 | 23 | 2012 |
Hematopoietic stem cells fail to regenerate following inflammatory challenge R Bogeska, P Kaschutnig, M Fawaz, AM Mikecin, M Büchler-Schäff, ... Biorxiv, 2020.08. 01.230433, 2020 | 14 | 2020 |
A myeloid tumor suppressor role for NOL3 RF Stanley, RT Piszczatowski, B Bartholdy, K Mitchell, WM McKimpson, ... JEM 214 (3), 753, 2017 | 9 | 2017 |
Stress-induced exit from dormancy alters redox signaling in HSCs, resulting in de novo DNA damage and bone marrow failure in the absence of a functional fanconi anemia … A Lier, D Walter, A Geiselhart, S Huntscha, D Brocks, I Bayindir, ... Experimental Hematology 42 (8), S45, 2014 | 2 | 2014 |
Preservation of patient whole blood preserves cancer immune cell biology at single cell resolution K Martin, C Kunihiro, J Abousoud, T Drennon, Y Li, S Marrache, N Raman, ... Cancer Research 84 (6_Supplement), 995-995, 2024 | | 2024 |
Blood Collection Workflow for Interrogation of Translational Samples with Single Cell Technologies D Walter, J Abousoud, T Drennon, C Kunihiro, K Martin, Y Li, N Raman, ... Blood 142 (Supplement 1), 7182-7182, 2023 | | 2023 |
Maximizing Multiomic Insights with High Throughput Single Cell Screening Q Gong, FN Tsai, D Walter, C Nemec, M Rahimi MOLECULAR THERAPY 30 (4), 158-159, 2022 | | 2022 |
No Evidence for Hematopoietic Stem Cell Self-Renewal in-Vivo Following Inflammatory Challenge R Bogeska, P Kaschutnig, SV Paffenholz, J Knoch, JP Mallm, M Fawaz, ... Blood 134, 456, 2019 | | 2019 |
HSCs completely fail to regenerate following inflammatory challenge, leading to aged hematopoiesis R Bogeska, P Kaschutnig, S Paffenholz, J Knoch, D Walter, JP Mallm, ... Experimental Hematology 53, S124, 2017 | | 2017 |
Hematopoietic Stem Cells Fail to Regenerate In Vivo Following Inflammatory Stress R Bogeska, P Kaschutnig, S Paffenholz, J Maassen, JP Mallm, F Wertek, ... Blood, The Journal of the American Society of Hematology 128 (22), 1472-1472, 2016 | | 2016 |
Altered HSC Metabolism in Response to Stress Leads to De Novo dna Damage and Cellular Attrition A Geiselhart, D Walter, A Lier, FB Thalheimer, S Huntscha, D Brocks, ... Blood 124 (21), 255, 2014 | | 2014 |
STRESS-INDUCED EXIT FROM QUIESCENCE INDUCES DE NOVO DNA DAMAGE IN HEMATOPOIETIC STEM CELLS AND RESULTS IN BONE MARROW FAILURE IN THE ABSENCE OF A FUNCTIONAL FANCONI ANEMIA … D Walter, A Lier, A Geiselhart, S Huntscha, D Brocks, I Bayindir, ... HAEMATOLOGICA 99, 261-261, 2014 | | 2014 |
HSC Exit From Dormancy Provokes De Novo DNA Damage, Leading To Bone Marrow Failure If Unresolved By The Fanconi Anemia Pathway D Walter, A Lier, A Geiselhart, S Huntscha, D Brocks, I Bayindir, ... Blood 122 (21), 799, 2013 | | 2013 |