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Poorvi Saraf
Poorvi Saraf
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Year
Design, synthesis, and biological evaluation of ferulic acid based 1, 3, 4-oxadiazole hybrids as multifunctional therapeutics for the treatment of Alzheimer’s disease
A Tripathi, PK Choubey, P Sharma, A Seth, P Saraf, SK Shrivastava
Bioorganic chemistry 95, 103506, 2020
422020
The molecular mechanism, targets, and novel molecules in the treatment of Alzheimer’s disease
A Verma, DK Waiker, B Bhardwaj, P Saraf, SK Shrivastava
Bioorganic Chemistry 119, 105562, 2022
372022
Novel 5, 6-diphenyl-1, 2, 4-triazine-3-thiol derivatives as dual COX-2/5-LOX inhibitors devoid of cardiotoxicity
P Saraf, PN Tripathi, MK Tripathi, A Tripathi, H Verma, DK Waiker, ...
Bioorganic Chemistry 129, 106147, 2022
92022
Drug reposition-based design, synthesis, and biological evaluation of dual inhibitors of acetylcholinesterase and β-Secretase for treatment of Alzheimer's disease
SK Shrivastava, AA Nivrutti, B Bhardwaj, DK Waiker, A Verma, PN Tripathi, ...
Journal of Molecular Structure 1262, 132979, 2022
92022
Design and development of benzyl piperazine linked 5-phenyl-1, 2, 4-triazole-3-thione conjugates as potential agents to combat Alzheimer’s disease
PVR Kiran, DK Waiker, A Verma, P Saraf, B Bhardwaj, H Kumar, A Singh, ...
Bioorganic Chemistry 139, 106749, 2023
72023
Development and Evaluation of Some Molecular Hybrids of N-(1-Benzylpiperidin-4-yl)-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio) as Multifunctional Agents to Combat …
DK Waiker, A Verma, P Saraf, G TA, S Krishnamurthy, RN Chaurasia, ...
ACS omega 8 (10), 9394-9414, 2023
72023
Synthesis, characterization, and biological evaluation of some novel ϒ-aminobutyric acid aminotransferase (GABA-AT) inhibitors
SK Shrivastava, O Sinha, M Kumar, DK Waiker, A Verma, PN Tripathi, ...
Medicinal Chemistry Research 31 (9), 1594-1610, 2022
22022
Design, Synthesis, and Biological Investigation of Quinazoline Derivatives as Multitargeting Therapeutics in Alzheimer’s Disease Therapy
A Verma, DK Waiker, N Singh, A Roy, N Singh, P Saraf, B Bhardwaj, ...
ACS Chemical Neuroscience, 2024
12024
Identifying inflammation-related targets of natural lactones using network pharmacology, molecular modeling and in vitro approaches
N Tripathi, P Saraf, N Bhardwaj, SK Shrivastava, SK Jain
Journal of Biomolecular Structure and Dynamics, 1-16, 2024
12024
Lead optimization based design, synthesis, and pharmacological evaluation of quinazoline derivatives as multi-targeting agents for Alzheimer's disease treatment
A Verma, DK Waiker, N Singh, A Singh, P Saraf, B Bhardwaj, P Kumar, ...
European Journal of Medicinal Chemistry 271, 116450, 2024
2024
Structure-Guided Design, Synthesis, and Biological Evaluation of Peripheral Anionic Site Selective and Brain Permeable Novel Oxadiazole-Piperazine Conjugates against Alzheimer …
A Singh, A Verma, B Bhardwaj, P Saraf, H Kumar, N Jain, DK Waiker, ...
ACS omega 9 (16), 18169-18182, 2024
2024
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