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Jonathan L Gillan
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High purity isolation of low density neutrophils casts doubt on their exceptionality in health and disease
GR Hardisty, F Llanwarne, D Minns, JL Gillan, DJ Davidson, ...
Frontiers in Immunology 12, 625922, 2021
332021
Targeting cystic fibrosis inflammation in the age of CFTR modulators: focus on macrophages
JL Gillan, DJ Davidson, RD Gray
European Respiratory Journal 57 (6), 2021
212021
CAGE sequencing reveals CFTR-dependent dysregulation of type I IFN signaling in activated cystic fibrosis macrophages
JL Gillan, M Chokshi, GR Hardisty, S Clohisey Hendry, ...
Science Advances 9 (21), eadg5128, 2023
22023
Macrophages from gut-corrected CF mice express human CFTR and lack a pro-inflammatory phenotype
JL Gillan, GR Hardisty, DJ Davidson, RD Gray
Journal of Cystic Fibrosis 21 (2), 370-374, 2022
22022
WS08-1 Calprotectin: the cystic fibrosis antigen regulates neutrophil migration during experimental lung inflammation and is a novel therapeutic target in cystic fibrosis
G Hardisty, S Law, J Gillan, EG Findlay, S Vermeren, D Davidson, R Gray
Journal of Cystic Fibrosis 18, S14, 2019
22019
443 Elexacaftor/tezacaftor/ivacaftor treatment promotes inflammation resolution in people with cystic fibrosis
N Robinson, G Hardisty, J Gillan, R Gray
Journal of Cystic Fibrosis 21, S253-S254, 2022
2022
Macrophage Dysfunction in Cystic fibrosis lung disease
J Gillan
The University of Edinburgh, 2021
2021
349: Tezacaftor/ivacaftor improves clinical outcomes but has only modest effects on inflammation in CF
N Robinson, G Hardisty, J Gillan, R Gray
Journal of Cystic Fibrosis 20, S167, 2021
2021
350: Elexacaftor-tezacaftor-ivacaftor treatment fundamentally changes the inflammatory landscape in people with CF
G Hardisty, N Robinson, J Gillan, L Hunt, R Gray
Journal of Cystic Fibrosis 20, S167, 2021
2021
WS12. 4 Tezacaftor/ivacaftor therapy induces increased airway neutrophilia and circulating neutrophil activation in cystic fibrosis
GR Hardisty, NJ Robinson, JL Gillan, RD Gray
Journal of Cystic Fibrosis 19, S20, 2020
2020
ePS3. 03 Probing the central role of macrophages in cystic fibrosis inflammation
JL Gillan, GR Hardisty, NJ Robinson, RD Gray
Journal of Cystic Fibrosis 19, S43, 2020
2020
CF ANTIGEN AS A THERAPEUTIC TARGET IN LUNG INFLAMMATION
G Hardisty, S Law, J Gillan, GE Findlay, RD Gray
PEDIATRIC PULMONOLOGY 54, S431-S432, 2019
2019
s100A9 regulates neutrophil migration during experimental lung inflammation and is a novel therapeutic target in respiratory disease
G Hardisty, S Law, J Gillan, EG Findlay, S Vermeren, D Davidson, R Gray
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 49, 70-71, 2019
2019
Neutrophil extracellular traps are elevated in Cystic Fibrosis sputum and associated with neutrophilic inflammation and lung function decline
SMP Law, G Hardisty, J Gillan, I Dransfield, RD Gray
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