DIMPLE: deep insertion, deletion, and missense mutation libraries for exploring protein variation in evolution, disease, and biology CB Macdonald, D Nedrud, PR Grimes, D Trinidad, JS Fraser, ... Genome biology 24 (1), 36, 2023 | 21 | 2023 |
The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics SW Yee, C Macdonald, D Mitrovic, X Zhou, ML Koleske, J Yang, DB Silva, ... bioRxiv, 2023 | 4 | 2023 |
Deep insertion, deletion, and missense mutation libraries for exploring protein variation in evolution, disease, and biology CB Macdonald, D Nedrud, PR Grimes, D Trinidad, JS Fraser, ... BioRxiv, 2022.07. 26.501589, 2022 | 4 | 2022 |
DIMPLE library generation and assembly protocol C Macdonald, D Nedrud, PR Grimes, D Trinidad, J Fraser, ... | 1 | 2023 |
The full spectrum of SLC22 OCT1 mutations illuminates the bridge between drug transporter biophysics and pharmacogenomics SW Yee, CB Macdonald, D Mitrovic, X Zhou, ML Koleske, J Yang, ... Molecular Cell 84 (10), 1932-1947. e10, 2024 | | 2024 |
Molecular basis of proton-sensing by G protein-coupled receptors MK Howard, N Hoppe, XP Huang, CB Macdonald, E Mehrotra, ... bioRxiv, 2024.04. 17.590000, 2024 | | 2024 |
Lipopolysaccharide integrity primes bacterial sensitivity to a cell wall-degrading intermicrobial toxin KL Trotta, BM Hayes, JP Schneider, J Wang, H Todor, PR Grimes, Z Zhao, ... bioRxiv, 2023 | | 2023 |