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Patrick Rockefeller Grimes
Patrick Rockefeller Grimes
Verified email at ucsf.edu
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Year
DIMPLE: deep insertion, deletion, and missense mutation libraries for exploring protein variation in evolution, disease, and biology
CB Macdonald, D Nedrud, PR Grimes, D Trinidad, JS Fraser, ...
Genome biology 24 (1), 36, 2023
212023
The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics
SW Yee, C Macdonald, D Mitrovic, X Zhou, ML Koleske, J Yang, DB Silva, ...
bioRxiv, 2023
42023
Deep insertion, deletion, and missense mutation libraries for exploring protein variation in evolution, disease, and biology
CB Macdonald, D Nedrud, PR Grimes, D Trinidad, JS Fraser, ...
BioRxiv, 2022.07. 26.501589, 2022
42022
DIMPLE library generation and assembly protocol
C Macdonald, D Nedrud, PR Grimes, D Trinidad, J Fraser, ...
12023
The full spectrum of SLC22 OCT1 mutations illuminates the bridge between drug transporter biophysics and pharmacogenomics
SW Yee, CB Macdonald, D Mitrovic, X Zhou, ML Koleske, J Yang, ...
Molecular Cell 84 (10), 1932-1947. e10, 2024
2024
Molecular basis of proton-sensing by G protein-coupled receptors
MK Howard, N Hoppe, XP Huang, CB Macdonald, E Mehrotra, ...
bioRxiv, 2024.04. 17.590000, 2024
2024
Lipopolysaccharide integrity primes bacterial sensitivity to a cell wall-degrading intermicrobial toxin
KL Trotta, BM Hayes, JP Schneider, J Wang, H Todor, PR Grimes, Z Zhao, ...
bioRxiv, 2023
2023
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