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Alexandra Duarte, Ph.D.
Alexandra Duarte, Ph.D.
Senior Scientist at HI-TRON Mainz
Verified email at dkfz-heidelberg.de
Title
Cited by
Cited by
Year
A living biobank of breast cancer organoids captures disease heterogeneity
N Sachs, J De Ligt, O Kopper, E Gogola, G Bounova, F Weeber, ...
Cell 172 (1), 373-386. e10, 2018
15022018
Replication fork stability confers chemoresistance in BRCA-deficient cells
A Ray Chaudhuri, E Callen, X Ding, E Gogola, AA Duarte, JE Lee, ...
Nature 535 (7612), 382-387, 2016
8292016
EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation
B Rondinelli, E Gogola, H Yücel, AA Duarte, M van de Ven, ...
Nature cell biology 19 (11), 1371-1378, 2017
3062017
Selective loss of PARG restores PARylation and counteracts PARP inhibitor-mediated synthetic lethality
E Gogola, AA Duarte, JR de Ruiter, WW Wiegant, JA Schmid, R de Bruijn, ...
Cancer cell 33 (6), 1078-1093. e12, 2018
2612018
BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance
AA Duarte, E Gogola, N Sachs, M Barazas, S Annunziato, J R De Ruiter, ...
Nature methods 15 (2), 134-140, 2018
1262018
A platinum complex that binds non-covalently to DNA and induces cell death via a different mechanism than cisplatin
K Suntharalingam, O Mendoza, AA Duarte, DJ Mann, R Vilar
Metallomics 5 (5), 514-523, 2013
1092013
A Tri‐copper (II) Complex Displaying DNA‐Cleaving Properties and Antiproliferative Activity Against Cancer Cells
K Suntharalingam, DJ Hunt, AA Duarte, AJP White, DJ Mann, R Vilar
Chemistry-A European Journal, 2012
982012
Heterologous expression of a Tpo1 homolog from Arabidopsis thaliana confers resistance to the herbicide 2,4-D and other chemical stresses in yeast
TR Cabrito, MC Teixeira, AA Duarte, P Duque, I Sá-Correia
Applied microbiology and biotechnology 84, 927-936, 2009
372009
Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1-versus BRCA2-deficient mammary tumors
J Bhin, MP Dias, E Gogola, F Rolfs, SR Piersma, R de Bruijn, JR de Ruiter, ...
Cell reports 42 (5), 2023
62023
MDC1 counteracts restrained replication fork restart and its loss causes chemoresistance in BRCA1/2-deficient mammary tumors
M Liptay, JS Barbosa, E Gogola, AA Duarte, D Dibitetto, JA Schmid, ...
bioRxiv, 2022.08. 18.504391, 2022
22022
H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours
D Dibitetto, M Liptay, F Vivalda, H Dogan, E Gogola, ...
Nature Communications 15 (1), 4430, 2024
2024
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