A living biobank of breast cancer organoids captures disease heterogeneity N Sachs, J De Ligt, O Kopper, E Gogola, G Bounova, F Weeber, ... Cell 172 (1), 373-386. e10, 2018 | 1762 | 2018 |
Replication fork stability confers chemoresistance in BRCA-deficient cells A Ray Chaudhuri, E Callen, X Ding, E Gogola, AA Duarte, JE Lee, ... Nature 535 (7612), 382-387, 2016 | 928 | 2016 |
EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation B Rondinelli, E Gogola, H Yücel, AA Duarte, M van de Ven, ... Nature cell biology 19 (11), 1371-1378, 2017 | 340 | 2017 |
Selective loss of PARG restores PARylation and counteracts PARP inhibitor-mediated synthetic lethality E Gogola, AA Duarte, JR de Ruiter, WW Wiegant, JA Schmid, R de Bruijn, ... Cancer cell 33 (6), 1078-1093. e12, 2018 | 310 | 2018 |
BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance AA Duarte, E Gogola, N Sachs, M Barazas, S Annunziato, J R De Ruiter, ... Nature methods 15 (2), 134-140, 2018 | 143 | 2018 |
A platinum complex that binds non-covalently to DNA and induces cell death via a different mechanism than cisplatin K Suntharalingam, O Mendoza, AA Duarte, DJ Mann, R Vilar Metallomics 5 (5), 514-523, 2013 | 110 | 2013 |
A Tri‐copper (II) Complex Displaying DNA‐Cleaving Properties and Antiproliferative Activity Against Cancer Cells K Suntharalingam, DJ Hunt, AA Duarte, AJP White, DJ Mann, R Vilar Chemistry-A European Journal, 2012 | 100 | 2012 |
Heterologous expression of a Tpo1 homolog from Arabidopsis thaliana confers resistance to the herbicide 2,4-D and other chemical stresses in yeast TR Cabrito, MC Teixeira, AA Duarte, P Duque, I Sá-Correia Applied microbiology and biotechnology 84, 927-936, 2009 | 42 | 2009 |
Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1-versus BRCA2-deficient mammary tumors J Bhin, MP Dias, E Gogola, F Rolfs, SR Piersma, R de Bruijn, JR de Ruiter, ... Cell reports 42 (5), 2023 | 23 | 2023 |
H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours D Dibitetto, M Liptay, F Vivalda, H Dogan, E Gogola, ... Nature communications 15 (1), 4430, 2024 | 11 | 2024 |
MDC1 counteracts restrained replication fork restart and its loss causes chemoresistance in BRCA1/2-deficient mammary tumors M Liptay, JS Barbosa, E Gogola, AA Duarte, D Dibitetto, JA Schmid, ... Biorxiv, 2022.08. 18.504391, 2022 | 3 | 2022 |