A framework for advancing our understanding of cancer-associated fibroblasts E Sahai, I Astsaturov, E Cukierman, DG DeNardo, M Egeblad, RM Evans, ... Nature Reviews Cancer 20 (3), 174-186, 2020 | 2540 | 2020 |
Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma AT Weeraratna, Y Jiang, G Hostetter, K Rosenblatt, P Duray, M Bittner, ... Cancer cell 1 (3), 279-288, 2002 | 1211 | 2002 |
Remodeling of the extracellular matrix through overexpression of collagen VI contributes to cisplatin resistance in ovarian cancer cells CA Sherman-Baust, AT Weeraratna, LBA Rangel, ES Pizer, KR Cho, ... Cancer cell 3 (4), 377-386, 2003 | 569 | 2003 |
Cancer-associated fibroblasts neutralize the anti-tumor effect of CSF1 receptor blockade by inducing PMN-MDSC infiltration of tumors V Kumar, L Donthireddy, D Marvel, T Condamine, F Wang, ... Cancer cell 32 (5), 654-668. e5, 2017 | 549 | 2017 |
How the ageing microenvironment influences tumour progression M Fane, AT Weeraratna Nature Reviews Cancer 20 (2), 89-106, 2020 | 516 | 2020 |
AGEMAP: a gene expression database for aging in mice JM Zahn, S Poosala, AB Owen, DK Ingram, A Lustig, A Carter, ... PLoS genetics 3 (11), e201, 2007 | 477 | 2007 |
The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition SK Dissanayake, M Wade, CE Johnson, MP O'Connell, PD Leotlela, ... Journal of Biological Chemistry 282 (23), 17259-17271, 2007 | 452 | 2007 |
Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases FA Attiga, PM Fernandez, AT Weeraratna, MJ Manyak, SR Patierno Cancer research 60 (16), 4629-4637, 2000 | 401 | 2000 |
sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance A Kaur, MR Webster, K Marchbank, R Behera, A Ndoye, CH Kugel, ... Nature 532 (7598), 250-254, 2016 | 360 | 2016 |
Age correlates with response to anti-PD1, reflecting age-related differences in intratumoral effector and regulatory T-cell populations CH Kugel III, SM Douglass, MR Webster, A Kaur, Q Liu, X Yin, SA Weiss, ... Clinical Cancer Research 24 (21), 5347-5356, 2018 | 310 | 2018 |
Remodeling of the collagen matrix in aging skin promotes melanoma metastasis and affects immune cell motility A Kaur, BL Ecker, SM Douglass, CH Kugel III, MR Webster, FV Almeida, ... Cancer discovery 9 (1), 64-81, 2019 | 307 | 2019 |
Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors G Zhang, DT Frederick, L Wu, Z Wei, C Krepler, S Srinivasan, YC Chae, ... The Journal of clinical investigation 126 (5), 1834-1856, 2016 | 260 | 2016 |
Ghrelin promotes thymopoiesis during aging VD Dixit, H Yang, Y Sun, AT Weeraratna, YH Youm, RG Smith, DD Taub The Journal of clinical investigation 117 (10), 2778-2790, 2007 | 254 | 2007 |
Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2 MP O'Connell, K Marchbank, MR Webster, AA Valiga, A Kaur, A Vultur, ... Cancer discovery 3 (12), 1378-1393, 2013 | 249 | 2013 |
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma MP O’Connell, JL Fiori, M Xu, AD Carter, BP Frank, TC Camilli, AD French, ... Oncogene 29 (1), 34-44, 2010 | 233 | 2010 |
Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells MC Caino, YC Chae, V Vaira, S Ferrero, M Nosotti, NM Martin, ... The Journal of clinical investigation 123 (7), 2907-2920, 2013 | 208 | 2013 |
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion MC Caino, JC Ghosh, YC Chae, V Vaira, DB Rivadeneira, A Faversani, ... Proceedings of the National Academy of Sciences 112 (28), 8638-8643, 2015 | 205 | 2015 |
Acid suspends the circadian clock in hypoxia through inhibition of mTOR ZE Walton, CH Patel, RC Brooks, Y Yu, A Ibrahim-Hashim, M Riddle, ... Cell 174 (1), 72-87. e32, 2018 | 200 | 2018 |
Modeling the two-way feedback between contractility and matrix realignment reveals a nonlinear mode of cancer cell invasion H Ahmadzadeh, MR Webster, R Behera, AM Jimenez Valencia, D Wirtz, ... Proceedings of the National Academy of Sciences 114 (9), E1617-E1626, 2017 | 191 | 2017 |
Claudin-1 overexpression in melanoma is regulated by PKC and contributes to melanoma cell motility PD Leotlela, MS Wade, PH Duray, MJ Rhode, HF Brown, DT Rosenthal, ... Oncogene 26 (26), 3846-3856, 2007 | 186 | 2007 |