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Krzysztof Kucharz
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Post-capillary venules are the key locus for transcytosis-mediated brain delivery of therapeutic nanoparticles
K Kucharz, K Kristensen, KB Johnsen, MA Lund, M Lønstrup, T Moos, ...
Nature communications 12 (1), 4121, 2021
792021
Apolipoprotein M-bound sphingosine-1-phosphate regulates blood–brain barrier paracellular permeability and transcytosis
M Mathiesen Janiurek, R Soylu-Kucharz, C Christoffersen, K Kucharz, ...
Elife 8, e49405, 2019
562019
Endogenous IFN-β signaling exerts anti-inflammatory actions in experimentally induced focal cerebral ischemia
AR Inácio, Y Liu, BH Clausen, M Svensson, K Kucharz, Y Yang, ...
Journal of neuroinflammation 12, 1-18, 2015
502015
NMDA receptor stimulation induces reversible fission of the neuronal endoplasmic reticulum
K Kucharz, M Krogh, AN Ng, H Toresson
PloS one 4 (4), e5250, 2009
452009
Blood–brain barrier transport of transferrin receptor-targeted nanoparticles
MS Thomsen, KB Johnsen, K Kucharz, M Lauritzen, T Moos
Pharmaceutics 14 (10), 2237, 2022
312022
PSD-95 uncoupling from NMDA receptors by Tat-N-dimer ameliorates neuronal depolarization in cortical spreading depression
K Kucharz, I Søndergaard Rasmussen, A Bach, K Strømgaard, ...
Journal of Cerebral Blood Flow & Metabolism 37 (5), 1820-1828, 2017
292017
Conjugation of therapeutic psd-95 inhibitors to the cell-penetrating peptide tat affects blood–brain barrier adherence, uptake, and permeation
M Kristensen, K Kucharz, E Felipe Alves Fernandes, K Strømgaard, ...
Pharmaceutics 12 (7), 661, 2020
222020
Rapid Fragmentation of the Endoplasmic Reticulum in Cortical Neurons of the Mouse Brain in situ Following Cardiac Arrest
K Kucharz, T Wieloch, H Toresson
Journal of Cerebral Blood Flow & Metabolism 31 (8), 1663-1667, 2011
222011
CaMKII-dependent endoplasmic reticulum fission by whisker stimulation and during cortical spreading depolarization
K Kucharz, M Lauritzen
Brain 141 (4), 1049-1062, 2018
202018
Potassium‐induced structural changes of the endoplasmic reticulum in pyramidal neurons in murine organotypic hippocampal slices
K Kucharz, T Wieloch, H Toresson
Journal of neuroscience research 89 (8), 1150-1159, 2011
152011
Fission and fusion of the neuronal endoplasmic reticulum
K Kucharz, T Wieloch, H Toresson
Translational stroke research 4, 652-662, 2013
142013
Shedding Light on the Blood–Brain Barrier Transport with Two-Photon Microscopy In Vivo
K Kucharz, N Kutuzov, O Zhukov, M Mathiesen Janiurek, M Lauritzen
Pharmaceutical Research 39 (7), 1457-1468, 2022
82022
Preserved blood-brain barrier and neurovascular coupling in female 5xFAD model of Alzheimer’s disease
O Zhukov, C He, R Soylu-Kucharz, C Cai, AD Lauritzen, BI Aldana, ...
Frontiers in Aging Neuroscience 15, 1089005, 2023
72023
Abstracts from the 20th international symposium on signal transduction at the blood-brain barriers
A Małecki, J Skipor-Lahuta, M Toborek, NJ Abbott, DA Antonetti, EJ Su, ...
Fluids and Barriers of the CNS 14, 1-23, 2017
22017
Two-photon microscopy in vivo reveals brain vessel type-specific loss of glycocalyx caused by apoM/S1P signaling impairment
K Kucharz, M Mathiesen Janiurek, C Christoffersen, M Lauritzen
BiorXiv, 2022.04. 11.487803, 2022
12022
Preserved blood-brain barrier and neurovascular coupling in 5xFAD mouse model of Alzheimer's disease in vivo
O Zhukov, C He, C Cai, AD Lauritzen, BI Aldana, M Lauritzen, K Kucharz, ...
JOURNAL OF VASCULAR RESEARCH 60 (SUPP 1), 54-54, 2023
2023
Preserved blood-brain barrier and neurovascular coupling in female 5xFAD model of Alzheimer’s
O Zhukov, C He, R Soylu-Kucharz, C Cai, AD Lauritzen, BI Aldana, ...
2023
A21 Assessment of satellite progenitor cell differentiation in hd skeletal muscle in vitro
S Hoque, K Kucharz, M Sjögren, A Neueder, M Orth, M Björkqvist, ...
Journal of Neurology, Neurosurgery & Psychiatry 92 (Suppl 1), A8-A9, 2021
2021
Two-photon fluorescence imaging: a platform to investigate cell-penetrating peptides and liposome-based nanocarriers for drug delivery across the heterogeneous BBB in vivo
K Kucharz, K Kristensen, M Kristensen, M Lund, T Andresen, B Brodin, ...
Journal of Cerebral Blood Flow and Metabolism 39 (1_suppl), 60-60, 2019
2019
Transport and metabolism of l‑glutamate in brain capillary endothelial cells and astrocytes
A Małecki, J Skipor-Lahuta, M Toborek, NJ Abbott, DA Antonetti, EJ Su, ...
BMC 14 (Suppl 2), 2017
2017
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