Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris: The Tabula Muris Consortium N Schaum, J Karkanias, NF Neff, AP May, SR Quake, T Wyss-Coray, ... Nature 562 (7727), 367, 2018 | 1338* | 2018 |
A single-cell transcriptomic atlas characterizes ageing tissues in the mouse Tabula Muris Consortium Nature 583 (7817), 590-595, 2020 | 756 | 2020 |
The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength W de Lau, WC Peng, P Gros, H Clevers Genes & development 28 (4), 305-316, 2014 | 666 | 2014 |
Ageing hallmarks exhibit organ-specific temporal signatures N Schaum, B Lehallier, O Hahn, R Pálovics, S Hosseinzadeh, SE Lee, ... Nature 583 (7817), 596-602, 2020 | 384 | 2020 |
Inflammatory cytokine TNFα promotes the long-term expansion of primary hepatocytes in 3D culture WC Peng, CY Logan, M Fish, T Anbarchian, F Aguisanda, ... Cell 175 (6), 1607-1619. e15, 2018 | 249 | 2018 |
Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids A Marsee, FJM Roos, MMA Verstegen, F Roos, M Verstegen, H Clevers, ... Cell Stem Cell 28 (5), 816-832, 2021 | 168 | 2021 |
Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5 WC Peng, W de Lau, F Forneris, JCM Granneman, M Huch, H Clevers, ... Cell reports 3 (6), 1885-1892, 2013 | 99 | 2013 |
Next-generation surrogate Wnts support organoid growth and deconvolute frizzled pleiotropy in vivo Y Miao, A Ha, W de Lau, K Yuki, AJM Santos, C You, MH Geurts, ... Cell Stem Cell 27 (5), 840-851. e6, 2020 | 93 | 2020 |
Structures of Wnt-antagonist ZNRF3 and its complex with R-spondin 1 and implications for signaling WC Peng, W de Lau, PK Madoori, F Forneris, JCM Granneman, H Clevers, ... PLoS One 8 (12), e83110, 2013 | 67 | 2013 |
Molecular hallmarks of heterochronic parabiosis at single-cell resolution R Pálovics, A Keller, N Schaum, W Tan, T Fehlmann, M Borja, F Kern, ... Nature 603 (7900), 309-314, 2022 | 60 | 2022 |
The strong dimerization of the transmembrane domain of the fibroblast growth factor receptor (FGFR) is modulated by Cterminal juxtamembrane residues WC Peng, X Lin, J Torres Protein Science 18 (2), 450-459, 2009 | 32 | 2009 |
Hepatocyte organoids and cell transplantation: What the future holds WC Peng, LJ Kraaier, TA Kluiver Experimental & Molecular Medicine 53 (10), 1512-1528, 2021 | 30 | 2021 |
Wnt signaling regulates hepatocyte cell division by a transcriptional repressor cascade Y Jin, T Anbarchian, P Wu, A Sarkar, M Fish, WC Peng, R Nusse Proceedings of the National Academy of Sciences 119 (30), e2203849119, 2022 | 14 | 2022 |
Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS IAEM van Belzen, C Cai, M van Tuil, S Badloe, E Strengman, A Janse, ... BMC cancer 23 (1), 618, 2023 | 12 | 2023 |
Low resolution structure of subunit b (b 22–156) of Escherichia coli F1FO ATP synthase in solution and the b−δ assembly R Priya, VS Tadwal, MW Roessle, S Gayen, C Hunke, WC Peng, J Torres, ... Journal of bioenergetics and biomembranes 40, 245-255, 2008 | 12 | 2008 |
Extracellular vesiclemediated delivery of CRISPR/Cas9 ribonucleoprotein complex targeting proprotein convertase subtilisinkexin type 9 (Pcsk9) in primary mouse hepatocytes NF Ilahibaks, TA Kluiver, OG de Jong, SCA de Jager, RM Schiffelers, ... Journal of Extracellular Vesicles 13 (1), 12389, 2024 | 2 | 2024 |
Dual targeting of cancer metabolome and stress antigens affects transcriptomic heterogeneity and efficacy of engineered T cells P Hernández-López, E van Diest, P Brazda, S Heijhuurs, A Meringa, ... Nature Immunology 25 (1), 88-101, 2024 | 1 | 2024 |
Multi-dimensional profiling of hepatoblastomas and patient-derived tumor organoids uncovers tumor subpopulations with divergent WNT activation profiles and identifies pan … TA Kluiver, Y Lu, SA Schubert, LJ Kraaier, F Ringnalda, P Lijnzaad, ... bioRxiv, 2023.08. 28.554783, 2023 | 1 | 2023 |
Long-Term Expansion of Murine Primary Hepatocyte Organoids TA Kluiver, LJ Kraaier, WC Peng Hepatocytes: Methods and Protocols, 1-13, 2022 | 1 | 2022 |
Targeting pediatric cancers via T-cell recognition of the monomorphic MHC class I-related protein MR1 AM Cornel, L van der Sman, JT van Dinter, M Arrabito, E Dunnebach, ... Journal for Immunotherapy of Cancer 12 (3), 2024 | | 2024 |